1.Research advances on the apolipoptrotein A-I mimetic peptides
Xiang LIU ; Zhijun OU ; Yan LI ; Jingsong OU
Chinese Journal of Biochemical Pharmaceutics 2016;36(12):20-24
High density lipoprotein cholesterol ( HDL-C) has received extensive attention because of its cardiovascular protective effects.Recent studies showed that HDL could promote reverse cholesterol transport ( RCT ) , be anti-inflammatory and antioxidant, and induce angiogenesis. Apolipoptrotein A-I (apoA-I), the most abundant protein of HDL, plays a pivotal role in the HDL mediated-functional activities.Short peptides based on the amphiphilic alpha helix structure of apoA-I have been designed and aimed at imitating the function of apoA-I.The function and metabolism of these mimetic peptides depend on their amino acids component and sequence , and have been proved to exert protection in against cardiovascular disease , infection, inflammation and oxidative damage, metabolic syndrome and tumor.Clinical trials confirmed their benefits, but high cost put them out of the practical applications..
2.An Investigation of Psychological Health Status of Middle-aged Intellectuals and Its Influencing Factors
Aihua OU ; Bing DENG ; Yan ZHU
Journal of Guangzhou University of Traditional Chinese Medicine 1999;0(02):-
[Objective] To probe into the psychological health status of middle-aged intellectuals and its influencing factors. [Methods]A cluster sampling of 1 474 middle-aged intellectuals was measured by the SCL-90 table and was analyzed by the Reliability Analysis, Principal Component Analysis and Analysis of Variance. [ Results ] The measurement table is highly reliable (Cronbach a = 0.949) and the Principle Component Analysis has main factors (A -1.97) and cumulative contribution rate is 80% . [Conclusion]Marital status, income and gender are the main influencing factors of psychological healthy status in middle-aged intellectuals.
3.A case report of genetic analysis in the OCRL1 gene in Lowe syndrome.
Fang JIANG ; Yan GAO ; Zhi-ying OU
Chinese Journal of Pediatrics 2012;50(9):708-709
Child
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Codon, Nonsense
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genetics
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DNA Mutational Analysis
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DNA Primers
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genetics
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Dent Disease
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diagnosis
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genetics
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Exons
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genetics
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Humans
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Infant
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Male
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Mutation
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Oculocerebrorenal Syndrome
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diagnosis
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genetics
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Phosphoric Monoester Hydrolases
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genetics
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Polymerase Chain Reaction
5.SIMPP analysis on major satisfaction of students
Lu ZHANG ; Hong AN ; Ou TAO ; Surong YAN ; Yun WANG
Chinese Journal of Medical Education Research 2015;(7):690-693
The major satisfaction of college students will influence their learning interest and motivation, and then influence their learning achievement and future employment. Under the guidance of the concept of the micro system engineering of the education reform, the degree of the major satis-faction of the students in TCM colleges is analyzed by SIMPP method. The results show that students' behavior mode such as their preview situation, teaching adaptation, course satisfaction, students' achievement and their attitude of poor academic performance is closely related to the degree of major satisfaction. Teachers can judge the degree of major satisfaction by following these pattern behaviors;improve the rationality and accuracy of the degree of major satisfaction.
6.SIMPP analysis on curriculum satisfaction of students
Fang LIU ; Sufen MIAO ; Ou TAO ; Surong YAN ; Yun WANG
Chinese Journal of Medical Education Research 2015;(7):686-689
The degree of satisfaction of the curriculum is related not only to the degree of the curriculum but also to the degree of the students' development. With the concept of teaching reform micro system engineering, using the SIMPP analysis of the degree of satisfaction of the curriculum, the relevant factors of the students are studied. The results show that, the learning state, learning objec-tives, and the education level of mother affect the students more easily on the curriculum satisfaction. Research shows, in the present curriculum condition, educators should guide the students to study hard, establish a clear and reasonable learning goal, give the students the introduction and analysis of the curriculum, can effectively improve the students on the curriculum satisfaction, enhance the enthusiasm of the study.
7.SIMPP analysis on learning diligence level of students
Sufen MIAO ; Lu ZHANG ; Ou TAO ; Surong YAN ; Yun WANG
Chinese Journal of Medical Education Research 2015;(7):654-658
Academic diligence level can not only directly affect the academic performance of students, but also affect the individual's emotional and physical health. In this study, through a question-naire survey of university students, with the method of SIMPP and the concept of the micro system engi-neering in higher education teaching reform, the related factors of diligence and the college students' behavior mode with respect to diligence are systematically analyzed. Analysis shows that, students' diligence level is affected not only by inherent factors such as clear learning objectives, learning state and after-school learning time, but also by the school ethos, the influence factors of the curriculum and parents' re-quirements.
8.SIMPP analysis on learning purpose of students
Ou TAO ; Yuanyan LIU ; Surong YAN ; Yun WANG
Chinese Journal of Medical Education Research 2015;(7):681-685
The clear learning objective is one of the important factors to determine the learning effect of college students. In order to analyze the factors affecting the formation process of college stu-dents' learning objectives, to explore the teaching mode that can be helpful for college students' clear learning objective, under the guidance of the concept of the reform of the teaching system, the SIMPP analysis of the students learning objective in the TCM colleges was carried out. Results showed that the related factors that affected student learning objectives included family factors, school principals and students' subjective factors. Teachers' observing students' learning status carefully, their understanding students' background, income and other social factors, mastering the degree of students' learning spe-cific goals and behavior model, and conducting the targeted and effective inventiveness are to help students clear learning objectives. The results provide the technology and method of operation for col-lege teachers to correctly guide different types of students to establish a clear learning objective.
9.SIMPP analysis on teacher's impact on students
Hong AN ; Fang LIU ; Ou TAO ; Surong YAN ; Yun WANG
Chinese Journal of Medical Education Research 2015;(7):667-671
The influence extent of students from teachers is related to the teaching effect , which means whether it can successfully promote the study of students and reach the expected teach-ing goal during the teaching process. To have a good teaching effect, guided by the micro-system en-gineering of teaching reform, we used SIMPP to analyze the related factors of the influence of students extent from teachers during the teaching process in TCM colleges and universities. The result shows that the influence extent from teachers is related to not only teachers themselves but students and their self-condition and family backgrounds as well. Going further in researching these factors and the related behavior patterns of influence extent of students from teachers is helpful to making the teach-ing more effective and more targeted.
10.The effect of head hypothermia on the large-acreage cerebral insarction(LCI) and hyperthermia patient's serum CORT,SOD and LPO level
Qin CHEN ; Xiaoyun OU ; Yan YANG ; Xinli LI ; Quncai LIU
Chinese Journal of Primary Medicine and Pharmacy 2006;0(01):-
Objective To study the changes of serum CORT,SOD and LPO in large-acreage cerebral insarction(LCI) and hyperthermia patients,and observe the effect of head hypothermia on them.Methods All cases of LCI were divided into head hypothermia treatment group(group A,n=49),warm water bath and glacial saline enema treatment group(group B,n=43),and health group(control group,group C,n=30).With the methods of radioimmunoassay,hydroxylamine oxidation and thirddialdehyde,the serum CORT,SOD and LPO level in the two groups were measured on the 2nd day after hospitalization and on the 2nd day,the 3rd day and the 4th day after hyperthermia.In addition,the life quality scores of the two groups were compared.Results The serum CORT,LPO of group A and group B were higher on the 2nd day after hospitaiization than the group C(P0.05),while the SOD were lower(P