1.Analysis of cervical cancer screening results in 13 297 rural women in Gaoping City
Chinese Journal of Primary Medicine and Pharmacy 2016;23(7):1052-1055
Objective To analyze the results of cervical cancer screening in 13 297 rural women in Gaoping during 2012-2015,and to explore more suitable way for rural women in the examination of cervical cancer.Methods According to theShanxi province rural women cervical cancer check project implementation plan,combined with the actual situation of Gaoping city,the gynecological examination of 13 297 married women in Gaoping city,vaginal and cervical secretions smear, cytology of cervical cytology ( TCT ) , to check the abnormal of the Department of Gynaecology and the abnormal cervical cytology, pathological examination of the cervix of the uterus with abnormal vaginal examination.Results A total of 6 965 cases of infection of the reproductive tract were examined, the prevalence rate was 52.38%.Among them,4 968 cases of cervicitis (37.36%),849 cases of trichomonas vaginitis (6.38%),Candida albicans vaginitis in 988 cases (7.43%),bacterial vaginal disease in 1 364 cases (10.26%), pelvic inflammatory disease in 1 348 cases (10.14%).Cervical cytology examination of ASC -US and the above cases in 418 cases (3.14%),ASC-US examination rate was 1.78%,the rate of ASC-H was 0.28%,the rate of LSIL was 0.60%,and the rate of HSIL was 0.47%.Detection of cervical precancerous lesions and cervical cancer cases,among them CIN I 81 cases,the incidence rate was 609.16/10 million,CIN II 29 cases,incidence rate was 218.09/10 million,16 cases of CIN,incidence rate was 120.33/10 million.The detection rate of precancerous lesions was 338.42/10 million.Cervical carcinoma in situ:1 case,9 cases of invasive cervical cancer,the detection rate of cervical cancer was 75.20/10 million.Conclusion Cervical cancer screening is helpful to improve the early detection rate of cervical cancer in rural women,safeguarding women's reproductive health.At the same time to carry out the census,vigorously promote health knowledge is also very important.
2.Study of Anti-CD9, CD10 immunotoxins to kill leukemiccell and the effect, on hemopoiesis
Chinese Journal of Immunology 1985;0(05):-
Immunotoxin consists of the antibody, which can specifically recognize relative antigen on the surface of leukemic cell, and intact ricin, which kill cell. It is very profitable to eliminate leukemic cell from bone marrow for prophylaxis of leukemia relapse after bone marrow transplantation. In the study, we reported that clongoenic leukemic cell (Nalm-6) were eliminated by two different immunotoxins (with CD9 and CD10). The inhibiting effect of immunotoxins in useful dose on the proliferation of hemopoietic progenitor cells (CFU-mix, BFU-E and CFU-GM) was not obviously.It is probably that immunotoxins will be used in autologous bone marrow transplation.
3.The bioethics and the international law:look back and unification
Chinese Medical Ethics 1995;0(02):-
Looking back to the history of the 20th century contributes to the rise of bioethics and the unification of international law on the present age.In the times of rapid scientific and economic development,it is either a core issue of bioethics or a starting point of international law that how humans should survive and establish a relationship with the nature.And a series of common behavior criteria for human being are being or will being established to seek a co-existent path between peoples as well as between human being and nature.
4.Preparation of 4-Paramisan Sodium Colon-specific Delivery Coated Tablets and the Determination of Its Drug-releasing Rate
China Pharmacy 2005;0(16):-
0.05).CONCLUSION:4-paramisan sodium oral colon-specific delivery coated tablets coated in turn with permeable and enteric soluble acrylic resin has ideal specific delivery and slow-release properties,the coating technology was stable and the reproducibility is good.
6.Identification of psychological factors in refractory functional gastrointestinal disorders
Chinese Journal of Practical Internal Medicine 2000;0(12):-
Functional gastrointestinal diseases(FGIDs) mainly include functional dyspepsia (FD),irritable bowel syndrome (IBS),functional constipation (FC) and functional abdominal pain syndrome (FAPS).In gastroenterology outpatient,42%~61% FGIDs patients have psychological factors,mostly depression and anxiety.The personality of these patients are almost introvert.Negative life events can be an incentive to lead to depression and anxiety which can aggravate the functional gastrointestinal symptoms.Clinical manifestations include long-term abdominal discomfort,abdominal pain (some with no fixed position),abdominal distension,anorexia,change in bowel habits,retrosternal and upper abdominal burning pain or overlapping symptoms.Some have obvious emotional performance.Dyspepsia symptom score of FD patients with mental disorders are higher than those who have no emotional performance and the gastric emptying decrease greatly than the latter.FGIDs treated by systemic therapy but with no improvement in symptoms may have somatization,compulsion,interpersonal tension,depression,anxiety and other psychological disorders.So psychological evaluation should be carried out to make early recognition for refractory functional gastrointestinal disorders.
7.Experience of LI Ji-ren in treating chronic nephritis albuminuria
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
TCM has dominance and characteristics in treating chronic nephritis, such as protecting the function of kidney and defering the kidney crocking up. Professor LI Ji-ren, a famous herbalist and the gainer of the special allowance of the State Council, has worked on clinic for 60 years. He Accumulates abundant experiences in treating chronic nephritis. On clinic, Professor Li advocates integratation of syndrome differentiation and disease differentiation, attaching importance to protect the basic of body and flexibility of syndrome differentiation. In aspects of medication, he begins with treating spleen and kidney,at the same time, harmonizing the qi and blood, detaching the clear and dirtiness, protecting other organs. Danbai Zhuanyin Prescription, containing thirteen herbal medicines, has marked effect on chronic nephritis albuminutia.
8.A model of rat osteosarcoma in nude mice using orthotopic implantation and studies on its biological characteristics
Journal of Chongqing Medical University 1986;0(02):-
Objective: To establish a model of rat osteosarcoma in nude mice and to study its biological characteristics.Methods: Intact tumor pieces were inoculated into the right tibia of nude mice.The nude mice were killed at different time and the growth of tumor and metastasis were observed.Result: The tumor growth rate was 100%.From the first week to the second week after implantation it grew into outer tissue from tibia,and widely invaded Soft tissue on the third week.Pulmonary metastasis took place from the fourth week to the fifth week,and the nude mice died of cachexia and respiratory failure resulting from the widely whole pulmonary metastasis on the sixth week or so.Conclusion: The tumor growth rate is high.The model simulates the clinical process of human osteosarcoma,and could be a satisfactory model for studying osteosarcoma.
9.RP-HPLC determination of triptolide in triptolide gel
Journal of Chongqing Medical University 2007;0(07):-
Objective:To develop an HPLC method for the assay of the content of triptolide in triptolide gel. Methods:The content of triptolide was measured by HPLC on Diamonsil C18 column(250mm?4.6mm i.d,5?m)using methanol-water(46∶54,v/v)as mobile phase,at a flow rate of 1.0ml/min. The UV detection was set at 220nm. Results:The calibration curve was proved to be linear in the range of 10.24~51.20?g/ml with a regression coeficient of 0.999 7. The average recovery of the method was 98.3%;RSD was 0.23%(n=5). Conclusion:This method is found to be rapid and accurate for the measurement of triptolide in triptolide gel.
10.Correlation between high mobility group protein 1,VEGF-C/D expressions and lymph node metastasis in colon cancer
Journal of Third Military Medical University 2003;0(11):-
Objective To discuss the correlation between the expressions of high mobility group protein box 1(HMGB1),VEGF-C/D and lymph node metastasis in colon cancer.Methods Forty-five colon cancer samples were stained by immunohistochemical method for VEGF-C/D,HMGB1.The correlations of VEGF-C/D,HMGB1 expressions and lymph node metastasis were analyzed statistically.Results Positive HMGB1 expression was in 33 specimens,lymph node metastasis was in 27 specimens with 23 specimens of positive HMGB1 and non-lymph node metastasis was in 18 specimens with 10 specimens of positive HMGB1.Positive VEGF-C expression was in 27 specimens with 20 in lymph node metastasis.The expression of HMGB1 was consistent with VEGF-C expression,and HMGB1 and VEGF-C expressions were closely correlated with lymph node metastasis,but not with age,sex,cellular differentiation.Conclusion HMGB1 and VEGF-C expression may become predictor to the prognosis of colon cancer patients.