Acupuncture ; education ; trends ; Biomedical Research ; trends ; China ; Humans ; Philosophy

Acupuncture Therapy ; China ; Health Services Accessibility ; Humans ; Public Health

Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Myasthenia Gravis ; therapy

Abstract?AIM: To comparatively analyze the efficacy and clinical value of cutting frontal muscular slap or not during frontalis aponeurosis flap suspension in treating congenital severe ptosis.?METHODS: Clinical data of 44 children ( 54 eyes ) with congenital severe ptosis treated in our hospital from May 2013 to October 2015 was retrospectively analyzed. Children included were divided into two groups according to the different ways of operation, observation group ( cutting frontal muscular slap ) and control group ( without cutting frontal muscular slap ) , 22 cases ( 27 eyes ) in each group. The general information, postoperative follow-up, eyelid closure and complication occurrence in two groups were compared.?RESULTS: The general information of the two groups had no statistical difference (P>0.05).After 1, 6mo, the cosmetic correction rate, the rate of overcorrection, and the rate of under correction in two groups had no statistical difference (P>0.05), but the activity of upper eyelid in observation group was bigger than that in control group (P<0.05).After 1, 6mo, the incomplete closure in two groups had no statistical difference ( P>0.05 ) , but eyelid fissure height in natural closed eyelids in control group was higher than that in observe group ( P<0.05 ).After 1mo, 2 eyes in control group were with abnormal feelings in frontal part, and 3 eyes in observation group.After 6mo, 2 eyes in control group were with abnormal feelings in frontal part, and 3 eyes in observation group.There were no complications such as exposure keratitis, eyelid margin deformity, infection, hematoma, and diplopia in two groups.?CONCLUSION: The total therapeutic effects of two different surgery procedures in treating severe congenital ptosis are quite similar.The surgery with cutting frontal muscular slap could improve the activity of upper eyelid and postoperative eyelid closure.

The utility of anticoagulants is a significant content of total quality management(TQA)of clinical laboratory.The accurate results of laboratory investigations are closely correlated witll appropriate application of blood anticoagulants.The paper reviews the utility field and effects on investigation result of different anticoagulants,and it also raises the current problems of using anticoagulants and Dut forward corresponding solutions.

Nanoliposomes are used as a delivery vehicle of drugs or genes in the targeted treatment of cancer and in gene therapy respectively. These treatment methods have shown better therapeutic effects when compared with conventional therapeutic methods. Nanoliposome are also being used to deliver imaging contrast agents in the targeted imaging of cancer cells and angiogenesis, which can result in better monitoring of patients' response to therapy.

Actins ; metabolism ; Animals ; Antigens, CD ; metabolism ; Cadherins ; metabolism ; Carotid Artery Injuries ; metabolism ; pathology ; Endothelium, Vascular ; metabolism ; ultrastructure ; Fluorescent Antibody Technique ; Microscopy, Confocal ; Rats ; Troponin ; metabolism

Antibiotics, Antineoplastic ; therapeutic use ; Apoptosis ; Cell Cycle ; Humans ; Neoplasms ; drug therapy ; metabolism ; pathology ; Neovascularization, Pathologic ; etiology ; Phosphatidylinositol 3-Kinases ; metabolism ; Protein Kinases ; physiology ; Proto-Oncogene Proteins c-akt ; metabolism ; Signal Transduction ; Sirolimus ; therapeutic use ; TOR Serine-Threonine Kinases

Morus alba L. (mulberry) is a well-known deciduous tree, belonging to the genus of Morus of Moraceae famlily. Its leaves, twigs, roots (bark) and fruits are widely used in the traditional Chinese medicine. The active constituents of mulberry contained flavonoids, alkaloids, steroids, coumarins, with the significant hypoglycemic, hypolipidemic, antihypertension, anti-oxidation, anti-inflammatory, anti-bacterial, anti-tumor and immunomodulatory activities. This review summarized the research progress of the major pharmacological activity, pharmacokinetics and drug-drug interaction based on CYPs and transporters of mulberry and its active constituents.
Alkaloids ; pharmacology ; Coumarins ; pharmacology ; Flavonoids ; pharmacology ; Fruit ; chemistry ; Herb-Drug Interactions ; Humans ; Medicine, Chinese Traditional ; Morus ; chemistry ; Plant Extracts ; pharmacology ; Plant Leaves ; chemistry ; Plant Roots ; chemistry ; Steroids ; pharmacology