This paper reports the situation of the treatment for stroke and introduces stroke unit (SU) in overseas hospitals : its important role in the emergency treatment and rehabilitation, the characteristics, advantages and managing modes. Moreover,it discusses the possibility and necessity of establishing SU with characteristics of traditional Chinese medicine.

Objective: To investigate the influence of ischemic and pinacidil preconditioning on the activity of NF-?B and its myocardial protective effects.Methods: Eighty isolated rabbit hearts were randomized into five groups(Group C?K?I?P?G).Hearts were removed and mounted in a Langendorff apparatus perfused with 37℃ oxygenated Krebs-Henselet buffer.All groups were subjected to gobal myocardial ischemia for 40 min and reperfusion for 60 min or 120 min.Cardiac functions were monitored at 10 min equilibration ?15 min?30 min?60 min and 120 min reperfusion;Coronary flow(CF) was measured at 10 min equilibration and 30 min reperfusion;Expression of NF-?B P65 was determined at 10 min equilibration?60 min and 120min reperfusion.Results:(1)After ischemic reperfusion,the recovery of cardiac function and CF in Group I and Group P was significantly superior to that in Group C and Group K(P

[Objective]To establish a scoring standard of operative risk assessment for the orthopaedic surgery and evaluate the reliability of it.[Method]Anivariable analysis was performed for the preoperative and intraoperative clinical data of 768 patients undergoing orthopaedic surgery from Jan.2001 to Dec.2008,the risk factors associated with orthopaedic surgery were selected.Then multivariable analysis with logistic regression was performed for the selected risk factors.The scoring standard was made through these data.Reliability of the standard was evaluated by predicting of 160 patients in spinal surgery from 2006 to 2008,comparing with the real situation of each operation.[Result]Anivariable analysis showed age,heart function,blood pressure,electrocardiogram,sternum,liver function,renal function,albumin,blood sugar,number of operative variables within four weeks,magnitude,blood loss preoperation,timing of operation were risk factors.[Conclusion]The ORAOS could appropriately predict the occurrence of patients' postoperative complication before operation.

To discuss long-term changes of refractive status in children after congenital cataract intraocular lens ( lOL) implantation and analyze its related influence factors.METHODS: Seventy cases ( 110 eyes ) with congenital cataract from January 2013 to January 2014 in our hospital were selected, according to the age of patients, they were divided into group A (<2 years old), group B (2~6 years old) , group C ( 7 ~ 12 years old ) . They were all given cataract extraction combined with lOL implantation in congenital cataract. Corneal curvature, axial length, refractive status of three groups after operation were compared, the influence factors ocular axis changes were analyzed. RESULTS: There were no statistically significant differences in corneal curvature of groups A, B, and C after operation ( P>0. 05 );The differences had statistical significances of the corneal curvature of group A after surgery and 3mo after operation (P<0. 05), there were no significant differences of the corneal curvature of group B, group C after surgery and 3mo after operation (P>0. 05);the corneal curvature 3mo after operation of group A was significantly higher than that of groups B and C (P<0. 05), there were no significant differences in the corneal curvature between group B, and group C after 3mo ( P>0. 05 ); There were no statistical significances on axial length after operation in groups A, B, and C (P>0. 05);Ocular axial length difference of group A 3mo after surgery was significantly higher than that of groups B and C ( P < 0. 05 ), ocular axial length had no statistical difference of group B, group c 3mo after surgery ( P>0. 05). Refractive status of three groups after operation showed myopia moving trend, refractive change rate and refractive diopter of group A after operation was significantly higher than that of group B, group C, the difference was statistically significant (P<0. 05). CONCLUSlON: After congenital cataract extraction combined with lOL implantation, patients present myopia refractive state trend. Performance of children below 2 years old is significant. The main factor of myopia is axial growth.

As one of the latest anti-angiogenic tumor molecular targeted therapy drugs,bevacizumab has achieved better clinical effect on the treatment of gastrointestinal cancer and ovarian cancer.This review focuses on the significance of bevacizumab combined with chemotherapy for the treatment of cervical cancer.

Objective To investigate the stability and comparability of recombinant human muscle creatine kinase isozyme(CK-MM)in different matrix,and to find out a suitable matrix as a reference material for application of CK measurement system.Methods The stability of the recombinant CK-MM was observed by measuring its catalytic activity in self-made matrix,anti-freeze additive matrix,the certified reference material(CRM)matrix and human serum matrix respectively.For understanding the commutability among different measurement system total CK catalytic activity in various concentration of human serum and the catalytic activity of recombinant CK-MM in different matrix specimen were measured with IFCC recommended reference method and routine reagent produced by Roche and Zhongsheng Diagnostic Company respectively.Results The recombinant CK-MM was stable for 25 days in the self-made matrix,23 days in CRM matrix and at least 240 days in antifreeze additive matrix stored at-20 ℃.The recombinant enzyme protein in self-made matrix and CRM matrix was commutable.Low concentrations of recombinant CK-MM in human serum and in anti-freeze additive matrix were also commutable.Conclusion The recombinant CK-MM had good stability and commutability in either self-made matrix or CRM matrix.It might be used as a candidate reference material for the determination of total creatine kinase in serum.

AIM:To set up the quality standard for Fuyang Jiedu Granules(Radix Sutellariae,Herba Scute-(llariae) Barbatae,Herba Epimedii,etc.). METHODS: Radix Scutellariae,Herba Scutellariae Barbatae and Herba Epimedii in preparation were identified by TLC.The content of baicalin was determined by HPLC on Agilent Eclipse XBD-C_(18) column. The mobile phase was methanol-phosphoric-water(47∶53∶0.2).The detection wavelength was at 280 nm. A Shim-pack VP-ODS column was used to determine icariin.The mobile phase consisted of 0.32% phosphoric acid-acetonitrile(75∶25).The detection wavelength was 270 nm. RESULTS: The spot on the thin layer plate was clear.The negative contral was not disturbed.The linear range of baicalin was in the range 0.122 12 ?g to 0.606 ?g.The average recovery was 99.59% with RSD of 2.16%.The linearity range of icariin was in the range 0.201 6 ?g-1.008 ?g.The average recovery was 99.49% with RSD of 1.31%.(CONCLUSION:) The methods are specific,simple,fast and accurate,and can be used for quality control of Fuyang Jiedu Granules.

Recent studies of immunology have aroused new interest in regulatory T cell for immune responses,and scientists have recognized that suppressor T cells exist in vivo and regulatory T(Treg) cells play a crucial role in mediating immune tolerance and preventing autoimmune diseases.This article reviews the types,characteristics,mechanisms,and roles of Treg in immune tolerance,aiming to offer some important theoretical evidence for the treatment of allograft rejection and autoimmune diseases.

objective: To study the relation of anchorage control and consumption of Nance arch. Methods: J hook anchorage, Nance arch with J hook anchorage, and Nance arch anchorage were used in 15, 12 and 16 cases for orthodontic treatment. All anchorage consumption of the first molar was measured on dental cast. Results: Forward movement of first molar in all of the cases was observed after treatmment( P

Objective:To observe oncosis in human peripheral blood T lymphocytes.Methods:Peripheral blood T lymphocytes of healthy adult was separated with Percoll(1.073 g/ml)and harvested by using nylon column.The cultured cells were divided into control and dexamethasone(DXM)group,and cell morphology was observed through light microscope,electron microscope and fluorescent microscope.And incidence rate of oncosis was analyzed by flow cytometry.Results:①Oncosis could be observed in cultured T lymphocyte after 96h.②In different concentrations of DXM group(1?10-6,1?10-5,1?10-4,1?10-3mol/L),The incidence of oncosis T lymphocytes was(3.49?0.42)%,(5.17?0.48)%,(8.44?0.72)%,(17.93?1.50)%.③During different cultured period(48,72,96,120h),The oncositic rate of T lymphocytes in DXM group was(0.53?0.10)%,(6.36?0.80)%,(20.60?1.59)%,(25.56?1.76)%.Conclusion:Oncosis can be seen in human peripheral blood T lymphocytes,and DXM could induce oncosis.