At present,lung diseases,particularly lung cancer,remain the major diseases that threaten human health,and the diagnosis,staging and re-staging and therapy evaluation of lung diseases are still the hot and difficult problems.PET(positron emission tomography)imaging can display the organic functions,metabolism,and other information at molecular level.PET has unique advantages and clinical application value in the diagnosis of lung diseases.This paper reviews the related literatures and presents typical cases for the discussion of PET/CT in lung diseases.

This paper analyzed some policies of new health care reform from the perspective of doctor -patient trust.The implementation of the policy of income and expenses in two lines has changed the management mode of township hospitals , eliminated some factors harming the doctor -patient relationship .The policy of equalization of public healthand other policies have guided the hospitals to change the way of service , service and health man-agement into the village increased the degree of doctor -patient trust .But at the same time , to ensure the new health care reform run smoothly , township hospitals introduced various ways of prescribing restraints .In addition , the policy of zero profit for basic drugs also brought some restrictions and regulations , resulting in a decline of satis-faction of patients , who have a tendency to blame the hospitals and doctors for these inconveniences .This misun-derstanding has becomed the new difficulties for doctor -patient trust as policy running .

0.05). After experimental cerebral hemorrhage for 4 hours of model group, blood pressure and P O 2 were obvious increased( P 0.05), but they were lower than model group at the meantime ( P

Objective The purpose of the studies was to explore the elective ways to enhance the ability of routine rest To - 99m - sestamibi (MIBI) myocardial scintigraphy to assess myocardial viability during the percutaneous transluminal coronary angioplasty (PTCA ) in assessing viable myocwhium. Methods Three methods, (1) rest- nitroglycerine augment, (2) rest-gated, (3) rest-delayed 99mc - MIBI myocardial scintigraphies, were performed in 20,30 and 10 patients with coronary artery disease treated with coronary revascularization. Results The results showed that in evaluating viable myocardium, the positive predictive values for methods(1 )-(3) were 95. 9%,68. 5% and 84.1%,mepectively, the negative predictive values were 68. 2%, 90. 1% and 90.0%, respecihvely, the predictive accuracy rates were 82. 5%, 77. 3% and 87.2%. Conclusions The results indicate that identification of viable myocardium with 98mTc - MIBI can be effectively enhanced with methods (1) - (3); the 99mTc - MIBI myocardial scintigraphy can provide objective data for evaluating treatment effects by coronary revascularization.

Objective To evaluate the efficacy of 90Sr-90Y applicator treatment for hemangioma by superficial ultrasound.Methods A total of 94 infants with hemangioma were retrospectively analyzed,including 37 males and 57 females (age range:1-12 months,mean =4.5 months).Thickness of hemangioma was measured by superficial ultrasound on the day before 90Sr-90Y applicator treatment,10 d and 3 months after treatment.Paired t test and x2 test were used to analyze data.ROC curve was analyzed to determine the tumor thickness which could be cured by one-cycle of treatment.Results Sixty-two cases were cured,29 cases had partial response and 3 cases had treatment failure.Thickness of hemangioma was (0.38 ±0.28)cm before treatment and (0.16±0.35) cm 3 months post-treatment and the difference was statistically significant (t=7.377,P＜0.05).The treatment effect of 90Sr-90Y applicator was not influenced by gender.According to the site of hemangioma,the curative rates were 20/38 in head & neck,22/33 in chest,20/23 in limbs.Only the difference between the curative rates in head & neck and limbs was statistically significant (x2 =7.478,P＜0.05).The treatment effect of 90Sr-90Y applicator was evaluated by the thickness of hemangioma under the skin at 3 months post-treatment and the area under the ROC was 0.93.The threshold of the thickness of hemangioma which could be cured by one-cycle of treatment was 0.32 cm with the sensitivity of 93.8％ and specificity of 85.5％.Conclusions The 90Sr-90Y applicator had a good treatment effect on pure hemangioma in infants,especially for those located in limbs and torso.The lesion with thickness less than 0.32 cm had a higher chance to be cured by one-cycle of treatment.

Objective:TCM Gegen extract(puerarin)and glucose tolerance factor(GTF) can regulate glucose metabolism and lipid metabolism.The purpose of research is to observe effect of the comoles compound of puerarin and GTF at molecular level on diet-induced obesity in rats.Methods:Male SD obese rats,induced by high fat feed,were randomly divided into fi ve groups:obese model group,positive medicine control group,the groups with small,middle and large of puerarin and GTF,and normal control group.The rats were given medicine for four weeks,body weight of every week,and lipid were measured.Results:After being fed the comoles compound of puerarin and GTF at molecular level for four weeks,the weight growth of rats was slowed down,the level of the following quota:TG,TC,serum insulin and serum leptin declined,the level of HDL-C increased.Compared with obese model group,there was a difference(P

CD133 has been confirmed as a stem cell surface marker in a variety of tumors.Specific markers of cancer stem cells in the thyroid cancer are not yet clear.Results of some studies showed that expression of CD133 was found in undifferentiated thyroid cancer cells which had the characteristics of stem cells.Those cells had the ability to self-renewal,multi-directional differentiation,potential development to cancer,and radio-and chemotherapy resistance.This article mainly views the progresses of CD133 in thyroid cancer research.

Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in a spectrum of cognitive functions and related to some psychiatric and neurodegenerative disorders such as AD,PD,autosomal dominant nocturnal frontal lobe epilepsy and schizophrenia.Nuclear medicine imaging of neuronal nAChRs in living human is a relatively new field.Halogenated analogs of 3 (2 (S)-2-azetidinylmethoxy) pyridine (A-85380) are the most widely used brain imaging radiotracers.In this review,the progress on the latest research on SPECT and PET using the analogs of A-85380 is summarized.

OBJECTIVE:To investigate therapeutic efficacy,safety and economics of budesonide for infant bronchiolitis based on salbutamot. METHODS:In prospective study,160 inpatient children with bronchiolitis during Oct. 2014-Apr. 2016 were divid-ed into observation group and control group according to admission order,with 80 cases in each group. Both groups received conventional treatments. Control group was given Salbutamol solution for inhalation 0.25 mL added into 0.9% Sodium chloride injection 3 mL,q8 h. Observation group was given Budesonide suspension for inhalation 2 mL added into 0.9% Sodium chlo-ride injection 1 mL+Salbutamol solution for inhalation 0.25 mL,q8 h. Both groups received oxygen driven inhalation,and treat-ed for 5-7 d. Clinical symptom disappearance time,hospitalization time and clinical efficacy were compared between 2 groups as well as therapy drug cost(aerosol inhalation,other therapy drugs). The occurrence of ADR was recorded. RESULTS:There was no statistical significance in cough disappearance time,wheezing disappearance time,lung rale disappearance time,tri-re-traction sign disappearance time and hospitalization time between 2 groups(P>0.05). There was no statistical significance in to-tal response rate between observation group (95.00%) and control group (92.50%)(P>0.05). The cost of inhalation drugs in observation group [(355.77±10.98)yuan] was significantly higher than control group [(26.83±2.86)yuan],with statistical signif-icance (P<0.05). There was no statistical significance in the cost of routine therapy drugs between 2 groups (P>0.05). There was no significant ADR between 2 groups during treatment. CONCLUSIONS:For infant bronchiolitis,aerosol inhalation of budesonide based on salbutamol sulfate can not significantly shorten disease,shorten hospitalization time and improve clinical ef-ficacy,but increase therapy cost.

Objective To explore the classical clinical features of mitochondrial encephalomyopathy with lactic acidosis and stroke like episodes (MELAS) syndrome.Methods The clinical data of 1 MELAS syndrome patient was analyzed retrospectively.Results This patient suffered from the symptoms of stroke such as speech disorder and abnormal behavior at the beginning.She had a medical history of maternal family.There were headache and seizure in the process of the disease.The result after a physical examination showed that the patient had hearing loss, visual field defect and decrease of muscle strength.The CT and MRI scan of head showed that the patient had a stroke like lesion which did not follow the distribution of blood vessels.The blood and cerebrospinal fluid examination has ruled out viral and autoimmune encephalitis.The final diagnosis of MELAS syndrome was confirmed by gene analysis.The gene mutation was the m.3243A>G mutation.The clinical symptoms of the patient were comprehensive and the imaging findings were typical.Conclusions Main clinical manifestations of MELAS syndrome are stroke like seizures, epilepsy, headache, dementia, hearing impairment, peripheral neuropathy, myopathy, lactic acidosis, diabetes and so on.Main imaging features of the disease are stroke like lesions, basal ganglia calcification and brain atrophy.