Objective:To evaluate the diagnostic accuracy and clinical applicability of the Simple Five item Scoring Scale for Sarcopenia (SARC-F) by systematic review and Meta-analysis.Methods:PubMed, The Cochrane Library, Wed of science, EMBASE, MEDLINE, Ovid, China HowNet database, China biomedical data, VIP database and Wanfang database were searched by computer, and all the researches related to SARC-F questionnaire's diagnosis of sarcopenia from the establishment of the database to March 1, 2020 were collected. Two researchers independently selected literature, extracted data, and evaluated the bias risk of the study. Revman 5.3 software, Stata16.0software were used to comprehensively evaluate the diagnostic value of SARC-F questionnaire for sarcopenia.Results:A total of 13 studies involving 8 860 patients were included. The results of meta-analysis showed that the sensitivity and specificity of the diagnostic criteria established by the European Working Group of Sarcopenia, the Asian Working Group for Sarcopenia and the International Working Group for Sarcopenia were used as the gold standard. The area under the receiver operating characteristic curve was 0.71, 0.69 and 0.67 respectively, and the Q-index was 0.659 3, 0.650 9 and 0.631 6.Conclusion:SARC-F questionnaire has a certain value in the screening and diagnosis of sarcopenia. In the future research, it is suggested to add the simple measurement of muscle quality on the basis of this scale to improve the accuracy of the questionnaire screening

Objective:To investigate the effect of early integrated Chinese and western medicine cluster intervention strategy on the prevention of intensive care unit acquired weakness(ICUAW).Methods:A total of 70 patients admitted to the ICU were divided into the intervention group and the control group by random digits table method with 35 cases each. The control group was given limb pressure treatment and limb rehabilitation exercise according to ICU nursing routine, and the intervention group was given early integrated Chinese and western medicine cluster intervention based on the control group, after intervention, the incidence of ICUAW, muscle strength, Barthel index score, mechanical ventilation time, length of stay in ICU and total length of stay between the two groups were compared.Results:The Medical Research Council score of the intervention group and control group were respectively (53.23±5.94) and (43.94±12.58), the Barthel index score were (79.57±7.80) and (66.14±19.25), the incidence of ICUAW were 17%(6/35) and 46%(16/35), the mechanical ventilation time were (162.26±72.27) and (254.06±126.22) h, the length of stay in ICU were (12.20±4.98) and (15.57±6.04) d, the total length of stay were (18.83±6.76) and (23.09±7.88) d, and the differences were statistically significant ( t values were -3.82-3.69, χ2 value was 6.63, P<0.05 or 0.01) . Conclusions:Early integrated Chinese and western medicine cluster intervention strategycan reduce the incidence of ICUAW, improve the muscle strength and daily life activities of patients, shorten the mechanical ventilation time, ICU length of stay and total length of stay in critically ill patients.