2.By nasal cavity approach resection of bigger pleomorphic adenoma in left skull base with nasal endoscope.
Yaguang ZHAN ; Xiaodong ZHAO ; Yongde JIN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(20):1620-1621
A 46-year-old female patient presented to our hospital with history of pharyngeal discomfort for 6 months. Physical examination showed that she had facial asymmetry, loss of the left nasolabial fold, rightward de- viation of uvula, swelling of the left soft palate. Magnetic resonance imaging revealed a bigger neoplasm in left pa- rapharyngeal space which invaded into left lateral skull base. The left internal carotid artery, vein and the styloid process was jostled backward. The primary clinical diagnosis is pleomorphic adenoma of the parapharyngeal space.
Adenoma, Pleomorphic
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surgery
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Carotid Artery, Internal
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Endoscopes
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Endoscopy
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Face
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abnormalities
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Facial Asymmetry
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congenital
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Female
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Humans
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Hyperplasia
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Magnetic Resonance Imaging
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Middle Aged
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Nasal Cavity
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Paranasal Sinuses
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Pharynx
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Skull Base Neoplasms
;
surgery
3.Clinical observation of amniotic membrane transplantation loaded with autologons marrow mesenchymal stem cells in treatment of pterygium patients
Huiyu GUO ; Yaguang ZHAN ; Meiou SUN
Chinese Journal of Primary Medicine and Pharmacy 2010;17(8):1037-1038
Objective To study the clinical effects of human amniotic membrane transplantation loaded with autologons marrow mesenchymal stem cells(MSCs) in treatment of pterygium patient. Methods Totally 10 patient (10 eyes) with primary giant pterygium aged 42 ~60 years(7 males and 3 females) were enrolled. All patients were informed consents. Bone marrow was sterilely collected by bone marrow aspiration. MSCs were harvested, purified and cultured. At the third passage,MSCs were incubated in amniotic membrane. After pterygium resection,amniotic membrane patch with cells surface upward was covered on surface of exposed sclera. Another simple amniotic membrane was sutured to protect transplanted cells. Results 1 ~ 3 days after dissection of corneal epithelial area was repaired,a week around later,migration of conjunctival epithelial gradually grew,about 10 ~ 14 days, absorption and fusion of amniotic membrane began. Follow-up of 6 months to 3 years, there was no recurrence. Conclusion After amniotic membrane loaded with MSCs were transplanted to the ocular surface ,corneal epithelium repaired rapidly ,transplanted amniotic membrane and conjunctival integrated, conjunctival irritation was few, ocular surface scar was light, the pterygium was no recurrence.