Objective: To investigate the effect of HCV persistent infection on biological behavior of human placental syncytiotrophoblast in vitro. Methods: Using Matrigel invasion assay,cell adhesive assay and migration assay to measure the effect of HCV persistent infection on invasive and relative adhesive and migration ability of human placental syncytiotrophoblast in vitro.Content of HCG in supernatant of the cultured medium was detected to evaluate the change of hormone synthesis and secretion of the infected syncytiotrophoblast.Results: Ability of invasion,adhesion,migration and function of hormone synthesis and secretion of infected syncytiotrophoblast decreased significantly in comparison with cells of control group(P

Experiments were performed on Wistar rats under the anaesthesia of urethane. Rats were put in a slant box and subjected to a third-degree burn over 35 per cent of the body surface scalded by immersion of the hind half of the body, including the tail, in a water bath maintained at 70℃ for 15 sec. The spontaneous electrical activity of the central cut stump of cervical vagus nerve-trunk and single vagus fibers was recorded. The purpose of the present study is to evaluate the activity of the parasympathetic nerve in scalded rats. The discharge of the cervical vagus nerve (nerve—trunk or single fiber) increased immediately, showing continuous discharge with higher frequency in the first 30-90 sec after scalding and the rhythm synchronizing with the respiration disappeared. After that, the impulses of the vagus nerve reduced and lasted for 15-30 min, then the frequency of discharge increased and approximated to the control level. During the period 60-360 min after scalding, two kinds of discharge of the vagus nerve-trunk were observed. Discharging frequency of seven rats out of the ten decreased gradually, while the frequency of discharge in the rest three rats continuously increased. The pattern of discharge of the vagus nerve revealed that the discharge of some fibers was strengthend, while that in some other fibers weakened or disappeared. The results mentioned above suggested that an immediate and transient increase of the excitation of the vagus center was present, afterwards the excitation of some central neurones was increased, while that of some other central neurones was depressed.

417 employees of construction and quarry site at 8 quarry companies were investigated in Hong Kong. All the respondents were interviewed with a diet questionnaire which included the following foods: a) meat; b) liver; c) lung; d) blood; e) fish and shellfish; f) eggs; g) fresh fruits; h) beans and peas; i) carrots; j) leafy green vegetables; k) milk and ic-ecream; 1) cream and butter; m ) fried foods; n ) margarine; o) lard; p) whloe wheat. Each subjects lung function was measured by Vitalograph as the machine which recorded the measure value, predict value according to the six, age and hight of the subject. FYCC (FVC meaure value/FVC predict value), FEV1 (FEV1 measure value/FEV1 predict value) and FEV1- FVCM (FEVl/FVC) were used as indicators for luug function in the paper and the demarcation between normal and poor lung function was 80% for FVCC and FEV1C while 75% for FEV1FVCM of predict value. The investigation results showed that the workers could pay more attention to food and health. They selected balanced diet and took more high-protein, high-vitamins and high-fiber foods such as fish, vegetables and fruits while high-fat or high-cholesterol foods such as animal viscera and lard were less taken. The results of Chi-squre analysis for dietary intake and lung function showed:1) None of the differences of food intakes between normal and poor FVCC reached statistical significance; 2) There were si-gnificent differences between normal and poor FEV1C in the intakes of liver and lung (P

Sixty Wistar rats were divided into 5 groups, 12 in each:1)Casein; 2) Fish powder (FP) ; 3) Fibrin; 4)Liver residue(LR) , 5)Nitrogen free(NF). The feeds for all groups of rats were at the level of 10% protein and at the same calories except NF. Growth test, nitrogen balance and recovery test were used and the levels of serum proteins and Hb were determined.The protein efficiency ratio (PER) of casein, FP, fibrin and LR were 1.90, 3.07, 2.61 and 1.28 respectively. Net protein ratio (NPR), apparent digestibility, true digestibility and net nitrogen ratio (NNR) were same as PER suggesting the protein quality of LR was low, FP was high and fibrin in the medium. The values of serum proteins also showed that 10% protein of LR could not maintain rats in health, but compared with casein and FP the nutritional quality of fibrin was high and could be used in feed industry or other products.The effects of proteins on hepatic microsomal enzyme were observed. The influence factors were discussed.

Motor imagery can improve upper limb and hand function of stroke patients. This review focused on the research progress of motor imagery about the way of treatment, the clinical effect, and the mechanism.

Basic research and clinical research on multiple myeloma (MM) have extensively progressed, as proven by the change in the definition of complete response (CR). With improvements in laboratory technology and introduction of novel agents, CR particu-larly emphasized both micro-and macro-models. The development of CR yielded therapeutic advances in MM and vice versa. The defi-nitions of response and treatment strategies were closely connected and improved. A need exists for further detailed studies on long-term disease control, such as optimal combination of agents. Given the shortage of new drugs and the distinctiveness of health in-surance, Chinese doctors should select the best treatment projects based on real-life situation in China.

Whether the hepatic pipestem fibrosis induced by schistosomiasis japonica can result in cirrhosis,confusion exists among parasitologists in China.Evidence from national and international pathologists and clinicians confirmed that the pipestem fibrosis could develop into cirrhosis undoubtedly.Owing to different pathogenic causes,the characters of cirrhosis are different.To re-understand cirrhosis induced by schistosomiasis japonica is of significance for the diagnosis and treatment of the advanced patient.

Objective To study diagnostic significance of spinal tuberculosis with PA and lateral view of X-ray film and CT.Methods X-ray and CT findings of 207 cases with spinal tuberculosis proved by pathology were respectively analysed.Results (1)The diagnostic rates by X-ray and CT was 93.7% and 98% respectively;(2)The diagnostic sensetivity in showing destruction of vertebral body and narrowing of interveterbral space was 74.4% and 89.9% respectively by radiography and CT;(3)The diagnostic rate only according to the destruction of vertebral body and narrowing of interveterbral space was nearly 90%;(4)Computer tomograph display of sequester formation,phamatosis in paraveterbral soft tissue,swelling of psoas muscle,involvement of bony veterbral canal,destruction of adnexa is better than the spinogram display.There is difference between two methods(?

The purpose of this investigation is to evaluate the excitability of the sympathetic nerves in burned rats. Pre ganglionic discharges from the cervical and the epinephronic sympathetic nerves and post-ganglionic discharges from the renal sympathetic nerve fibers were recorded in rats anaesthized with urethane. After burning, the discharges of the sympathetic nerves of the rats at first showed continuous high frequency soon followed by a decline. After that, the sympathetic efferent electrical activity became very active again, displaying a high amplitude and high frequency.These results suggest that the sympathetic nerves system exhibits periodic excitatory changes in burned rats with a excitation-inhibition-excitation cycle.

Objective To evaluate fixation of anatomic plate by comparing ou tc omes of surgery and conservative therapy for proximal humeral fractures. Methods 24 cases of proximal humeral fractures were fixed with anatomic plate, lag scre ws and kirschner wire. 19 cases were managed with conservative therapy of manual reduction and external wood splint fixation. The results were evaluated by Neer classification and Constant-murley scoring system. Results All the case were f ollowed up 10 to 19 months(averaging 11.5 months). In the 24 operated cases, 11 patients were graded as excellent, 8 as good, 4 as fair, 1 as poor. In the 19 ca ses of conservative therapy, 6 patients were graded as excellent, 7 as good, 6 a s fair, most of which were Neer types Ⅲand Ⅳ. The operative treatment produced better outcome than the censervative treatment ,far the difference was statisti cally significant(P