Purpose: This correlation study was designed to understand clinical nurses' political interest, nursing professionalism, and intention to participate in politics, as well as the impact of political interest and nursing professionalism on intention to political participation. Method: A total of 187 clinical nurses from a general hospital in Seoul were considered for this study. The collected data were analyzed using SPSS/WIN 24.0, which included descriptive statistics, t-tests, analysis of variance (ANOVA), multiple regression analysis, and Scheffé’s test. Results: Political interest (β=.46, p<.001), nursing professionalism (β=.17, p=.007), manager or higher (β=.19, p=.018), and age under 24 years of age (β=.14, p=.038) were all statistically significant predictors of political participation. The explanatory power of these factors was 35.6% (R 2 =.39, Adj. R 2 =.36). Conclusion This study revealed the relationship between nursing professionalism and intention to participate in politics, which has not been previously investigated in clinical nurses. This study is significant as it suggests the necessity and direction of future nursing professionalism education programs.

Purpose: This correlation study was designed to understand clinical nurses' political interest, nursing professionalism, and intention to participate in politics, as well as the impact of political interest and nursing professionalism on intention to political participation. Method: A total of 187 clinical nurses from a general hospital in Seoul were considered for this study. The collected data were analyzed using SPSS/WIN 24.0, which included descriptive statistics, t-tests, analysis of variance (ANOVA), multiple regression analysis, and Scheffé’s test. Results: Political interest (β=.46, p<.001), nursing professionalism (β=.17, p=.007), manager or higher (β=.19, p=.018), and age under 24 years of age (β=.14, p=.038) were all statistically significant predictors of political participation. The explanatory power of these factors was 35.6% (R 2 =.39, Adj. R 2 =.36). Conclusion This study revealed the relationship between nursing professionalism and intention to participate in politics, which has not been previously investigated in clinical nurses. This study is significant as it suggests the necessity and direction of future nursing professionalism education programs.

Purpose: This correlation study was designed to understand clinical nurses' political interest, nursing professionalism, and intention to participate in politics, as well as the impact of political interest and nursing professionalism on intention to political participation. Method: A total of 187 clinical nurses from a general hospital in Seoul were considered for this study. The collected data were analyzed using SPSS/WIN 24.0, which included descriptive statistics, t-tests, analysis of variance (ANOVA), multiple regression analysis, and Scheffé’s test. Results: Political interest (β=.46, p<.001), nursing professionalism (β=.17, p=.007), manager or higher (β=.19, p=.018), and age under 24 years of age (β=.14, p=.038) were all statistically significant predictors of political participation. The explanatory power of these factors was 35.6% (R 2 =.39, Adj. R 2 =.36). Conclusion This study revealed the relationship between nursing professionalism and intention to participate in politics, which has not been previously investigated in clinical nurses. This study is significant as it suggests the necessity and direction of future nursing professionalism education programs.

Purpose: This correlation study was designed to understand clinical nurses' political interest, nursing professionalism, and intention to participate in politics, as well as the impact of political interest and nursing professionalism on intention to political participation. Method: A total of 187 clinical nurses from a general hospital in Seoul were considered for this study. The collected data were analyzed using SPSS/WIN 24.0, which included descriptive statistics, t-tests, analysis of variance (ANOVA), multiple regression analysis, and Scheffé’s test. Results: Political interest (β=.46, p<.001), nursing professionalism (β=.17, p=.007), manager or higher (β=.19, p=.018), and age under 24 years of age (β=.14, p=.038) were all statistically significant predictors of political participation. The explanatory power of these factors was 35.6% (R 2 =.39, Adj. R 2 =.36). Conclusion This study revealed the relationship between nursing professionalism and intention to participate in politics, which has not been previously investigated in clinical nurses. This study is significant as it suggests the necessity and direction of future nursing professionalism education programs.

PURPOSE: The risk of invasive fungal infection is greater for allogeneic hematopoietic stem cell transplantation (HSCT) than for autologous transplantation. Therefore, many transplantation centers use antifungal prophylaxis for allogeneic HSCT, however, there exists no standard guidelines or consensus regarding autologous HSCT. MATERIALS AND METHODS: A prospective double-blind randomized study was conducted in autologous HSCT recipients who were divided into prophylaxis and empirical treatment groups, and we investigated the efficacy of itraconazole prophylaxis in pediatric autologous HSCT. RESULTS: Total 87 autologous HSCT episodes in 55 children with high-risk solid tumors were studied. No invasive fungal infections occurred in either group. However, patients in the prophylaxis group had a significantly shorter duration of fever (p < 0.05) and received antibacterial treatment of shorter duration (p < 0.05) with fewer numbers of antibiotics (p < 0.05 for the use of second line antibiotics) than those in the empirical group. No significant additional adverse events were found with itraconazole prophylaxis. CONCLUSION: Although beneficial effects such as a shorter duration of fever and reduced need for antibiotic use were observed in the prophylaxis group, the results were not sufficient to draw a definite recommendation about the routine use of antifungal prophylaxis in pediatric autologous HSCT recipients with high-risk solid tumors (Trial registration: NCT00336531).
Anti-Bacterial Agents/therapeutic use ; Antifungal Agents/*therapeutic use ; Child, Preschool ; Cost-Benefit Analysis ; Double-Blind Method ; Hematopoietic Stem Cell Transplantation/*adverse effects ; Humans ; Itraconazole/*therapeutic use ; Mycoses/*prevention & control ; Neoplasms/*surgery ; Prospective Studies ; Risk Factors ; Transplantation, Autologous ; Treatment Outcome