1.Mutation analysis of microRNA-7 gene in Chinese patients with Parkinson's disease.
Xuewei ZHANG ; Jifeng GUO ; Sanxi AI ; Yaceng HU ; Qiying SUN ; Qian XU ; Zhanyun LU ; Kai LI ; Xiaoli DONG ; Lu SHEN ; Hong JIANG ; Qian PAN ; Kun XIA ; Xinxiang YAN ; Beisha TANG
Journal of Central South University(Medical Sciences) 2012;37(12):1189-1192
OBJECTIVE:
To investigate the mutation of small sequence changes in microRNA-7 gene in Chinese patients with Parkinson's disease (PD).
METHODS:
We analyzed miR-7 variants in 225 PD patients from Chinese Han group by DNA sequence.
RESULTS:
None of the patients had miR-7 variants.
CONCLUSION
MiR-7 variation is not associated with PD in Chinese patients.
Aged
;
Base Sequence
;
China
;
ethnology
;
Female
;
Humans
;
Male
;
MicroRNAs
;
genetics
;
Middle Aged
;
Molecular Sequence Data
;
Mutation
;
Parkinson Disease
;
genetics
Result Analysis
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