Clinical Medicine ; Humans ; Neoplasms ; prevention & control ; Periodicals as Topic ; Research

With the development of computer techniques and medical imaging examining methods , precise radiotherapy is becoming the major direction of radiotherapy for tuomors. Both of tumor control probability and normal tissue complication probability are improved with precise radiotherapy. This paper critically review the value of PET-CT and breathing control in precise radiotherapy for non-small-cell lung cancer (NSCLC).

ObjectiveTo explore the effect of the cognition dysfunction on the stroke rehabilitation.MethodsThe loewenstein Occupational Therapy Cognitive Assessment Battery (LOTCA), Fugl Meyer motor scale, functional independence measure were carried out to evaluate the function of 66 stroke patients before and after rehabilitation.ResultsThe rehabilitation process of motor and independent function of patients who had suffered from cognition dysfunction was latered than that of patients who had not suffered from cognition dysfunction, and cognition dysfunction had a closed relationship with stroke rehabilitation.ConclusionCognition dysfunction directly has a influence to stroke rehabilitation, both special and comprehensive methods in rehabilitation process, improve cognition function, decrease its influence to the stroke rehabilitation.

Objective: To study the dosage application of herbs in class formulas of KaixinSan recorded in Prescriptions of the Bureau of Taiping People's Welfare Pharmacy (Taiping Huimin Hejiju Fang), Essential Recipes for Emergent Use Worth A Thousand Gold (Beiji Qianjin Yao Fang) and Records of Approved Cases of Ancient and Recent Times (Gujin Luyan) and their actions on depression. Method: According to the dosage proportion of different herbs in the three formulas in the three books, two methods were adopted in terms of decocting different herbs separately and mixing them thereafter(group of decocting separately) as well as extracting after decocted all the herbs together (group of decocting together). Classical anti-depression mice models--forced swimming and tail suspending experiments were observed. The data of immovability time of mice were analyzed by statistics. Result: All the class formulas of KaixinSan which have the same medication but different proportion in the three medical books can reduce the immovability time of mice in forced swimming and tail suspending experiments. But the action of KaixinSan recorded in Prescriptions of the Bureau of Taiping People's Welfare Pharmacy was prominent, and the action of the group of decocting together was superior to that of separated decocting. There was significant difference between the group of decocting together in low dosage and the controlled one (P

ObjectiveTo explore the effects of extended nursing intervention (ENI) in nursing ability of discharged patients with intubation of T-tubes.Methods Eighty-two patients with biliary diseases discharged with intubation of T-tubes were equally divided into two groups.The patients in the experiment group were treated with ENI and those in the control group were treated with conventional nursing.Each group received routine nursing and health education before discharge.All patients were followed up by a self-designed written questionnaire.Data regarding patients’ compliance behavior,knowledge of the diseases and satisfaction were collected and analyzed.Result Significant differences were observed between the two groups,the patients in the experiment group exhibiting better compliance behavior,their knowledge of their diseases improved and the rate of satisfaction higher (P<0.05). Conclusion ENI may be effective for the discharged patients with intubation of T-tubes to improve their compliance behavior, enhance their knowledge of their diseases and raise the rate of satisfaction.

OBJECTIVE: To investigate the kinetic and thermodynamic characteristics of adsorption of avilamycin on silica gel. METHODS: By measuring the adsorption of avilamycin on silica gel at different temperatures, the adsorption kinetics curves and adsorption isotherm were drawn, and the kinetics and thermodynamic parameters were studied. RESULTS: The adsorption of avilamycin on silica gel could be described well by Pseudo-second-order model. The adsorption process had feature of shrinking nonreactive core model, and the internal diffusion was the main rate-limiting step. The equilibrium adsorption data of avilamycin on silica gel fit the Langmuir isotherms well. The thermodynamic parameters were as follows:change in entropy (ΔS) was 108.115 2 J·mol-1·K-1, change in enthalpy (ΔH) was 24.654 6 J·mol-1, and changes in free energy (ΔG) were -8.752 9, -8.104 3, and -7.455 6 J·mol-1 at 309, 303 and 297 K, respectively. CONCLUSION: The RESULTS: of this study provide a theoretical basis for further study on the isolation and purification of high purity avilamycin by silica gel.

OBJECTIVE: To optimize the formulation of avilamycin self-microemulsifying drug delivery system (SMEDDS) using central composite design-response surface method and evaluate its quality. METHODS: The compositions of avilamycin SMEDDS were screened by solubility experiment and self-emulsifying grading test. The formulation was optimized using Design Expert Software, taking particle size and Zeta potential as dependent variables and the usage amounts of oil, surfactant and cosurfactant as independent variables. RESULTS: The optimized formulation was quickly and conveniently obtained as follows: 36.67% propylene glycollaurate, 42.83% cremophor RH40 and 20.50% diethylene glycol monoethyl ether.The average diameter of the preparation was (28.34±0.06)nm, the Zeta potential was (-1.98±0.24)mV and PDI was (0.15±0.005). CONCLUSION: The central composite design and response surface method is useful for the formula optimization of avilamycin self-microemulsifying drug delivery system.The prediction accuracy of the established mode1 is good.

Actins ; metabolism ; Adult ; Desmin ; metabolism ; Diagnosis, Differential ; Histiocytoma, Malignant Fibrous ; pathology ; Humans ; Immunohistochemistry ; Leiomyoma ; pathology ; Leiomyosarcoma ; metabolism ; pathology ; surgery ; Male ; Mediastinal Neoplasms ; metabolism ; pathology ; surgery ; Vimentin ; metabolism

DNA Repair ; genetics ; DNA-Binding Proteins ; genetics ; Drug Resistance, Multiple ; Drug Resistance, Neoplasm ; Endonucleases ; genetics ; Humans ; Neoplasms ; drug therapy ; genetics ; Nuclear Proteins ; genetics ; Organoplatinum Compounds ; therapeutic use ; Platinum Compounds ; therapeutic use ; Polymorphism, Single Nucleotide ; Transcription Factors ; genetics ; X-ray Repair Cross Complementing Protein 1 ; Xeroderma Pigmentosum Group D Protein ; genetics

Catheter Ablation ; Consensus Development Conferences as Topic ; Humans ; Microsurgery ; Neoplasms ; therapy ; Radiotherapy Planning, Computer-Assisted ; Radiotherapy, Intensity-Modulated