1.Modern Research Progress of Relationship between Heart and Emotion Xu Y a1, Li Pengtao2
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(6):1451-1455
Heart dominating mind is one of the main contents in the visceral manifestation theory of tradi-tional Chinese medicine ( TCM ) theory . This article summed up documents , clinical studies , basic experimental studies , and modern scientific researches to review the research results of the relationship between heart and emotion . The connotation of heart dominating mind theory in modern biology was interpreted . And the scien-tificity of TCM theory was explained .
2.Evaluation of spatiotemporal image correlation on fetal cardiac systolic function in normal pregnancy
Xu ZHAO ; Ya YANG ; Rongjuan LI
Chongqing Medicine 2013;(25):2961-2963
Objective To investigate the evaluation value of spatiotemporal image correlation (STIC) on fetal cardiac systolic function .Methods The fetal cardiac cycle images were collected by the four-dimensional(4D) STIC ultrasound technique in 160 normal singleton pregnancies .The virtual organ computer-aided analysis(VOCAL) technique was used to measure the ventricular end-systolic volume (VESV) and ventricular end -diastolic volumes(VEDV) .The stroke volume(SV) ,ejection fraction(EF) and cardiac output(CO) were calculated .Results VESV ,VEDV together with SV and CO in normal pregnancy were increased with gestation week increase .EF remained constant with advancing gestational week .VESV ,VEDV ,SV ,CO and EF of right ventricle were all larger than those of the left ventricle .Conclusion The fetal cardiac systolic function in normal pregnancy is increased with gestational age increase ,the right heart systolic function is superior to the left heart .
3.Relationship between cognitive emotion regulation and behavioral inhibition/activation system of adolescents
Yanzhang LI ; Li XU ; Ya KUANG ; Yun XU
Chinese Journal of Behavioral Medicine and Brain Science 2013;(1):53-55
Objective To explore the relationships between cognitive emotion regulation and behavioral inhibition system(BIS)/behavioral activation system (BAS) of adolescents.Methods Seven hundreds forty-two adolescents were tested by Behavioral Inhibition/Activation System Scale(BIS/BAS Scale) and Cognitive Emotion Regulation Questionnaire Chinese version (CERQ-C).Results (1) Maladaptive emotion regulation,such as selfblame,rumination,catastrophizing and blame others were positively corrected with BIS (r =0.13 ~ 0.38,P <0.01).But adaptive ER had no significantly correlations with BIS (r =-0.05,P > 0.05).Maladaptive emotion regulation was positively correlated with BAS (r =0.24,P < 0.01),and adaptive emotion regulation was negatively correlated with BAS(r =-0.028,P< 0.01).(2)Except acceptance,BIS/BAS had significant effect on the other eight cognitive emotion regulation(P < 0.01).Conclusion BIS/BAS are closely related with cognitive emotion regulation,and have important influences on selection of adolescents'cognitive emotion regulation.
4.Protective effect of tetrahydroxystilbene glucoside on hippocampal neurons damage induced by glutamate in rats
Ya-li LI ; Ling ZHAO ; Yan-ling XU ; Lin LI
Chinese Journal of Rehabilitation Theory and Practice 2004;10(12):751-753
ObjectiveTo observe the protective effect of tetrahydroxystilbene glucoside (TSG) on rats' hippocampal neuronal damage induced by glutamate (Glu) in the culture.MethodsHippocampus was isolated from newborn SD rats and dispersedly cultured in the medium for 9 days. Neurons were incubated with TSG (5—100μmol/L) for 24h, the cells were washed twice with Lock's solution without Mg2+,then Glu 500 μmol/L was added. Thirty min later, the reaction was terminated by washing the monolayer cells twice with the Lock's solution and then cultures were kept at 37℃ for 24h. Cell viability was measured by MTT method and cell membrane damage was determined by LDH leakage; with Fluo-3/AM as an intracellular calcium indicator and added into the bathing medium, fluorescent intensity of intracellular free calcium were observed through laser scanning confocal microscopy (LSCM).ResultsAfter the treatment with 5—100μmol/L TSG for 24h, the decrease of cell viability and the increase of LDH leakage caused by Glu was obviously resisted dose dependently. TSG inhibited increase of Ca2+ in cytoplasm, compared with model group.ConclusionTSG can significantly promote the cell viability and reduce the cell membrane damage in Glu treating hippocampal neurons. The neuroprotective activities of TGS is mediated by inhibiting Ca2+ overload in cytoplasm.
5.Effect of Panax notoginseng saponins on myocardial Gs? mRNA expression of seriously scalded rat
Haigang ZHANG ; Xiaohui LI ; Shuhui LI ; Hongmei XU ; Ya TAN ;
Chinese Traditional and Herbal Drugs 1994;0(11):-
Object To investigate the effects of Panax notoginseng saponins (PNS) on myocardial Gs? mRNA expression of seriously scalded rat. Methods A 30% skin full thickness scald model was produced by immersing rat in 95 ℃ water for 10 s. The effects of PNS on myocardial Gs? mRNA level were observed with dot blotting hybridization and in situ hybridization technique; effects on cAMP and adenyl cyclase (AC) activities were determined with radioimmunoassay. Results Myocardial Gs? mRNA, AC activity and cAMP content were reduced significantly 3 h after scalding. PNS (100, 200 mg/kg) could markedly increase the level of myocardial Gs? mRNA expression. The elevated quantity was correlated markedly with PNS dosage (r = 0.95, P
6.Effects of propofol on metabolism of neurotransmitters in different regions of CNS in healthy volunteers
Hui ZHANG ; Li-Xian XU ; Ya-Li GE ; Al ET ;
Chinese Journal of Anesthesiology 1995;0(12):-
Objective To investigate the changes in the metabolism of neurotransmitters in different regions of the brain induced by propofol in healthy volunteers using the proton magnetic resonance spectroscopy (MRS) technology.Methods IH-MRS was performed in ten 20-40 year old healthy volunteers. Each volunteer underwent MRS scan twice. The first MRS scan was performed when they were conscious as baseline control value. The second scan was performed during target-controlled infusion (TCI) of propofol. The target effect-site concentration was set at 3.0 ?g?ml-1. Volume of interest (VOI) included sensory cortex, motor cortex, thalamus, hippocampus and basal ganglia. The metabolites in the spectra included N-acetyl-aspartic acid (NAA), glutamic acid (Glu), GABA, choline compounds (Cho) and creatine (Cr) .Results During TCI of propofol MAP and RR were significantly decreased ( P 0.05) as compared to the baseline value when the volunteers were conscious. During TCI of propofol the NAA content in thalamus and hippocampus, Glu content in thalamus, hippocampus and basal ganglia and Cho content in all the 5 regions of the brain were significantly decreased ( P
7.Analysis of apnea in 229 cases of very low birth weight infants.
Xiu-jing WU ; Ya-ping XU ; Li-ping SHI
Chinese Journal of Pediatrics 2003;41(8):622-623
Apnea
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epidemiology
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pathology
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therapy
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Birth Weight
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China
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epidemiology
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Female
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Gestational Age
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Humans
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Infant, Newborn
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Infant, Very Low Birth Weight
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Male
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Risk Factors
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Time Factors
8.Regulatory effect of electroacupuncture on heart and stomach of rats.
Bin-bin REN ; Zh YU ; Ya-li WANG ; Bin XU
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(10):1212-1215
OBJECTIVETo explore different regulatory effects of electroacupuncture (EA) at the same acupoint on the heart and the stomach.
METHODSEighty male SD rats were randomly divided into eight groups equally, i.e., the Neiguan (PC6) group, the Quchi (LI11) group, the Tianshu (ST25) group, the Danzhong (RN17) group, the Zusanli (ST36) group, the Sanyinjiao (SP6) group, the Xinshu (BL15) group, and the Weishu (BL21) group, 10 in each group. The regulatory effects of EA (2/15 Hz, 3 mA, 2 min) at different acupoints on the gastric motility (intragastric pressure) and the cardiac function (the left ventricular pressure) were observed. The mean values of effect of two-min pre-EA and after-EA were compared.
RESULTSCompared with the pre-EA in the same group, the left ventricular pressure decreased in the Neiguan (PC6) group, the Quchi (LI11) group, the Danzhong (RN17) group, the Sanyinjiao (SP6) group, and the Xinshu (BL15) group (P <0.05). The intragastric pressure increased in the Quchi (LI11) group, the Zusanli (ST36) group, the Sanyinjiao (SP6) group, and the Xinshu (BL15) group, while it decreased in the Tianshu (ST25) group, the Danzhong (RN17) group, and the Weishu (BL21) group (P <0.05). The difference of the left ventricular pressure was sequenced from high to low as Xinshu (BL15) >Danzhong (RN17) >Neiguan (PC6) >Sanyinjiao (SP6) >Quchi (LI11). The difference of the intragastric pressure was sequenced from high to low as Tianshu (ST25) >Weishu (BL21) > Xinshu (BL15) > Danzhong (RN17) > Zusanli (ST36) > Sanyinjiao (SP6) > Quchi (LI11).
CONCLUSIONSEA at the same acupoint (2/15 Hz, 3 mA) showed different regulatory effects on the heart and stomach. There existed some difference in the direction and size due to the acupoint location, meridians, dominant nerve segment or relating organs. A fixed effect direction to the specific target was also shown.
Acupuncture Points ; Animals ; Electroacupuncture ; Heart ; physiology ; Male ; Meridians ; Rats, Wistar ; Stomach ; physiology
10.Morphology and AFLP analysis of tetraploid plantlets of Atractylodes macrocephala.
Hong-juan WANG ; Ya-ting LI ; Zeng-xu XIANG
China Journal of Chinese Materia Medica 2015;40(3):404-409
In order to investigate the genetic basis of morphological variation of tetraploid plantlets of Atractylodes macrocephala, diploid plantlets were taken as experimental material, sterile filtration colchicine was used to soak 0.5-1.0 cm long buds. The difference between morphology and stomatal of diploid and tetraploid of A. macrocephala was compared, and genome polymorphism was explored by AFLP. The results showed that the buds dipped in 0.1% colchicine solution for 36 h was optimal conditions to induce tetraploid of A. macrocephala with induction rate of 32.0%. Morphological indexes such as leaf area index, leaf length and width, the density of stomas and the number of chloroplast of tetraploid were distinctly different from diploid. Four hundred and fifty-one bands ranging with 80-500 bp were amplified with 24 pairs of primers, the rate of polymorphism was 32.59%. These amplification sites of diploid were different from tetraploid of A. macrocephala, and the differences in morphology of them were reflected in the DNA polymorphism.
Amplified Fragment Length Polymorphism Analysis
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methods
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Atractylodes
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genetics
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Sequence Analysis, DNA
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Tetraploidy