1.Relationship of retinal lesions and postoperative visual acuity of cataract phacoemulsification
International Eye Science 2014;(12):2204-2206
AlM: To study the relationship of retinal associated lesions and postoperative visual acuity of cataract phacoemulsification.
METHODS:From February 2013 to February 2014, 120 cases with given cataract phacoemulsification were divided into observation group and control group. Cases in observation group were with of retinal associated lesions, those in control group were without retinal associated lesions. The best corrected visual acuity, ision acuity, visual evoked potential, intraocular pressure were compared between two groups.
RESULTS:Two weeks after surgery, visual acuity in observation group was higher than those of before therapy. Visual acuity recovery rate of observation group was significantly slower than that of control group; best corrected vision, visual acuity in observation group was significantly lower than that in control group;observation group's amplitude (12. 01±4. 50ü V) was significantly lower than control group, incubation period (114. 29±11. 32ms) was significantly higher than control group; After 6, 12, 24h, intraocular pressure (23. 64 ± 4. 28, 24. 12 ± 5. 13 and 18. 28± 3. 22mmHg) were significantly higher than control group.
CONCLUSlON: Retinal associated lesions can lead to visual evoked potential change, elevated lOP, affect postoperative visual recovery level.
2.Observation on therapeutic effect of polycystic ovary syndrome of damp-phlegm constitution treated with embedding therapy on back-shu points and front-mu points combined with needle-pricking therapy on Sifeng (EX-UE 10).
Rong CHEN ; Cong WANG ; Qing-Ya YAN
Chinese Acupuncture & Moxibustion 2014;34(4):355-358
OBJECTIVETo investigate the effectiveness of polycystic ovary syndrome (PCOS) of damp-phlegm constitution treated with embedding therapy on back-shu points and front-mu points and needle-pricking therapy on Sifeng (EX-UE 10).
METHODSEighty-five patients were randomly divided into 2 groups of observation group (42 cases) and control group (43 cases). Embedding therapy on back-shu points and front-mu points and needle-pricking therapy on Sifeng (EX-UE 10) were applied to the observation group. Points such as Zhongwan (CV 12), Guanyuan (CV 4), Tianshu (ST 25), Zhangmen (LR 13), Jingmen (GB 25), Qimen (LR 14), Ganshu (BL 18), Weishu (BL 21), Pishu (BL 20), Shenshu (BL 23), Dachangshu (BL 25) and Xiaochangshu (BL 27), etc. were adopted for embedding therapy. At the same time, needle-pricking therapy on Sifeng (EX-UE 10) was also applied once a week. 0. 5 g metformin hydrochloride tablet was given to the control group, once a day for the first week, and twice a day from the second week. Estimation on therapeutic effect was made for both groups after 3 months treatment. Change of symptoms and signs scores, fasting insulin (FINS), 2 hour insulin after meal (2hINS) and insulin resistance index (HOMA-IR) of both groups before and after treatment were observed, and therapeutic effect estimated.
RESULTSThe total effective rate of the observation group is 97. 6% (41/42), and that of the control group was 95. 4% (41/43). There was no significant difference between the two groups (P>0. 05). Scores of symptoms and signs after treatment were significantly improved in both groups (all P<0. 01), and the observation group was better than the control group (7.01+/-4.23 vs 8. 47+/-2. 82,P<0. 05). Compare with those before the treatment, FINS, 2hINS and HOMA-IR after the treatment were all decreased in both groups (all P<0. 05). The comparison between the two groups showed that differences of FIN had no statistic significance (P>0. 05) after the treatment, while both differences of 2hINS and HOMA-IR had statistic significance [ 2hlNS: (443. 531+/- 93. 90) pmol/L vs (621.29+/-93. 87) pmol/L ; HOMA-IR: 4. 88+/-0. 30 vs 5.06+/-0. 32, both P<0. 05]. The improvement of 2hINS and HOMA-IR in the observation group was better than that of the control group.
CONCLUSIONTreatment of PCOS of damp-phlegm constitution with embedding therapy on back-shu points and front-mu points and needle-pricking therapy on Sifeng (EX-UE 10) have positive effect, which can effectively reduce the insulin resistance, meanwhile, reduce the side-effects of western medication.
Acupuncture Points ; Acupuncture Therapy ; Adult ; Female ; Humans ; Polycystic Ovary Syndrome ; therapy ; Treatment Outcome ; Young Adult
3.Correlation between tear osmolarity and the dry eye severity
Chinese Journal of Experimental Ophthalmology 2012;(11):1022-1025
Background There still is no a uniform diagnostic criteria for increasing population of dry eye.Studies showed that high tear osmotic pressure is one of causes of a variety of ocular surface discomfort,and the change of tear osmolality has been included in the definition of dry eye syndrome by Dry Eye World Study Group (DEWS) in 2007.It is very clinically significant to study the relationship of tear osmolality with dry eye.Objective This clinical trial was to study the correlation between tear osmolarity and dry eye severity based on Preferred Practice Pattern(PPP)of DEWS.Methods A descriptive study was performed.Fifty-four eyes of 54 patients with dry eye disease were asked to complete an evaluation of dry eye signs and symptoms questionnaire based on PPP.The ocular anterior segment was examined under the slit lamp biomicroscope.Cornealfluorescein staining,tear-film breakup time (BUT),Schirmer test Ⅰ (S Ⅰ t)without anesthesia were performed,and tear sample was collected for tear imageology and tear osmolarity admeasurement.The correlation between dry eye score with tear osmolarity was evaluated using Pearson linear correlation analysis.Written informed consent as obtained prior to any relevant medical procedure.Results The ratio of male and female patients was 1: 2 in this study.The negative correlations were found between tear osmolarity with S Ⅰ t or BUT(r =-0.456,-0.699,P<0.01),and significantly positive correlations were found between tear osmolarity with tear imaging examination,corneal fluorescein staining,conjunctival hyperemia or dry eye symptom score(r=0.545,0.686,0.691,0.803,P<0.01).Conclusions As a diagnostic method,tear osmolarity can objectively reflects dry eye severity.It can be a biomarker in dry eye severity grade when combined with clinical symptom.
4.Determination of lead in workplace air by portable X-ray fluorescence spectrometry.
Juntong LIU ; Yan LIU ; Ya CHEN ; Yan ZHAO ; Tong WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2015;33(4):299-301
OBJECTIVETo investigate the permance index ofof portable X-ray fluorescence spectrometer in the determination of lead on filter membrane and to provide data for the determination of lead in workplace air.
METHODSIrradiated with X-ray, the lead would emit specific X-ray fluorescence during the process from the excited state back to the ground state. Rapid determination of lead was completed using fluorescence energy and wave length for qualitative analysis and fluorescence intensity for quantitative measurement. Under set conditions, a series of customized calibration samples were measured to create a standard curve for quantitative analysis of lead on filter membrane.
RESULTSThe regression equation obtained using a portable X-ray fluorescence spectrometer to determine the lead on filter membrane was y=0.004x-0.182 (r2= 0.9999). The linear range was 0.00 -10.40 mg/m3, the minimum detectable concentration was 0.53 µg/m3, and the minimum quantifiable concentration was 1.76µg/m3. The relative standard deviation (RSD) of within-run precision of samples with different concentrations was 0.48%-6.22%, the RSD of between-run precision was 2.51%-5.09%, and the degree of accuracy was in the calibration range of standard samples.
CONCLUSIONPortable X-ray fluorescence spectrometry is a simple, rapid, repeatable, and accurate method for the determination of lead on filter membrane.
Air Pollutants, Occupational ; analysis ; Lead ; analysis ; Spectrometry, X-Ray Emission ; Workplace
5.Short and long-term outcomes of placental transfusion in very low birth weight infants: a meta analysis
Haiyan WANG ; Yan JIANG ; Haiqing LENG ; Ya LUO ; Laishuan WANG
Chinese Journal of Perinatal Medicine 2015;18(10):747-754
Objective To investigate the risks and benefits of interventions promoting placental transfusion (PT) at delivery [delayed cord clamping (DCC) or umbilical cord milking (UCM)] compared with early cord clamping (ECC) on outcomes among very low birth weight infants (VLBWI).Methods A systematic search was conducted of PubMed, EMBASE, ClinicalTrials.gov, China Academic Journal Network Publishing Database and Wanfang Medical Databases (January 1965 to July 2014) for randomized controlled trial (RCT) articles relating to PT strategies (DCC and UCM) in VLBWI.The Cochrane Handbook 5.1.0 was used to evaluate the methodological quality and RevMan 5.3 software from Cochrane Collaboration was used for metaanalysis.The fixed effect or random effect model was adopted according to the result of heterogeneity, Results We identified 14 eligible studies describing a total of 659 neonates with an average birth weight < 1 500 g.There were eight studies for DCC and six studies for UCM.Compared with the control, benefits of greater PT decreased any grade intraventricular hemorrhage (IVH) (nine studies, OR=0.49, 95%CI: 0.32-0.77, P < 0.01), increased the blood pressure at four hours of life (eight studies, MD=4.42, 95%CI: 3.85-4.98, P < 0.01), and also showed higher initial hemoglobin (Hb) level (six studies, MD=3.52, 95%CI: 1.67-5.37, P < 0.01) and lower incidence of sepsis during the hospital stay (five studies, OR=0.46, 95%CI: 0.26-0.83, P=0.01).No differences were observed between the groups about the fllowing indicators (all P > 0.05): 5-minute Apgar scores (MD=0.01,95%CI:-0.21-0.22), admission temperature (MD=0.13, 95%CI:-0.15 to 0.41), peak serum bilirubin levels (MD=0.59, 95%CI:-0.13 to 1.31), initial reported hematocrit (MD=3.48, 95%CI:-0.46 to 7.43), mortality before discharge (OR=0.63, 95%CI:0.31-1.25), Bell's stage 2 or greater necrotizing enterocolitis (OR=0.62 ,95%CI: 0.29-1.33), rates of transfusion due to anemia (OR=0.63, 95%CI: 0.35-1.15) and oxygen therapy at 36 weeks of corrected age (OR=0.79, 95%CI: 0.46-1.34).Conclusions It is suggested that enhanced PT (both DCC and UCM) at birth is safe and provide better neonatal outcomes than ECC for those VLBWI, most notably reduces the overall IVH occurrence and lower the incidence of sepsis.The optimal umbilical cord clamping practice and UCM among VLBWI infants remains uncertain and long-term neurodevelopmental outcomes are warranted.
7.Immunohistochemical study on the expression of caspase, bax, bcl-2 and c-kit after SCI in Bufo bufogargarizan.
Ping LI ; Yu ZHANG ; Ya-Fei CAI ; Yan WANG
Chinese Journal of Applied Physiology 2011;27(4):399-401
Animals
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Bufo bufo
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Caspase 3
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genetics
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metabolism
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Female
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Immunohistochemistry
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Male
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Proto-Oncogene Proteins c-bcl-2
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genetics
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metabolism
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Proto-Oncogene Proteins c-kit
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genetics
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metabolism
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Spinal Cord
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metabolism
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Spinal Cord Injuries
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metabolism
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bcl-2-Associated X Protein
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genetics
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metabolism
9.The correlation of thrombosis occurring and experimental phenotypic and genotypic in six inherited thrombophilia cases.
Ya-nan CAO ; Yan XIA ; Xie-feng WANG
Chinese Journal of Hematology 2013;34(3):256-258
Adult
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Female
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Genotype
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Humans
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Male
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Middle Aged
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Phenotype
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Thrombophilia
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genetics
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Thrombosis
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Young Adult