Objective To investigate the relationship between metabolic syndrome and the chronic kidnev disease in both Han and Uyguer populations.Methods 1027 cases were enrolled during 2006-3 to 2007-1 from the First Affiliated Hospital,Xiniiang University.According to the identification of chronic kidnev disease(CKD)and minor renal dysfunction,these patients were divided into different groups. The correlation between the components of metabolic syndrome and CKD was examined.T test,Chi-square test and logistic regression were used.Results (1)CKD and mild CKD prevalence were 37.4%and 24.0% in all the cases.(2)The Ievel of age,low-density lipoprotein cholesterol,trigly-ceride,high-density lipoprotein cholesterol.uric acid in Han people were higher than those among Uyguer people while body mass index.systolic blood pressure and diastolic blood pressure were lower than those Uyguer people. (3)There were no significant differences found between Han and Uyguer people in different metabolic components.(4)In the group which had only one metabolic component disjunction,the diabetic group accounted for big proportion while in those patients with two or more metabolic component dislunction,hypertension and obesity were significantly high in Han people but diabetes plus obesity were seen in Uyguer people.(5)Diabetes,obesity,metabolic components,uric acid were independent factors associated with CKD and mild CKD.Conclusion There were close connection between metabolic syndrome and CKD found in Xinjiang area.