1. Three-dimensional CT angiography simulates operative approaches for intracranial aneurysms
Academic Journal of Second Military Medical University 2010;30(5):532-536
Objective: To simulate the surgical approaches for intracranial aneurysms using three-dimensional CT angiography (3D-CTA) ,so as to assess the value of 3D-CTA in the microneurosurgery for ruptured intracranial aneurysms. Methods1 Totally 134 patients with spontaneous subarachnoid hemorrhage caused by ruptured intracranial aneurysm were confirmed by operation. All the patients were examined by CTA before operation and surgical simulation was conducted. Some patients were examined by the pre-operative DSA (digital subtract angiography). The findings of pre-operation CTA,DSA and intra-operative findings were compared and the clinical value of cerebral 3D-CTA was analyzed. Results1 3D-CTA discovered 162 aneurysms out of a total of 163 in 134 patients. The sensitivity and specificity of 3D-CTA for diagnosis of ruptured intracranial aneurysm were 99. 4% and ioo% , respectively. Moreover, pre-operation examination with 3D-CTA clearly displayed the location,size, and shape of aneurysms, the axis direction of the aneurysmatic summits and the width of aneurysmatic neck. Furthermore,the spatial relations between the parent aneurysm artery, the aneurysm, the periphery vessel and bony structures were also demonstrated. These findings were in accordance with the intra-operative findings. There was no rupture during exploration. The Glasgow outcome score was 5 in 85 patients,4 in 22,3 in 17,2 in 6,and 1 in 4. Conclusion1 The conventional pre-operative 3D-CTA examination can simulate surgery for patients with ruptured intracranial aneurysms, and it can help to design the operative approach and improve the successful rate of operation.
2.Modern Research Progress of Relationship between Heart and Emotion Xu Y a1, Li Pengtao2
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(6):1451-1455
Heart dominating mind is one of the main contents in the visceral manifestation theory of tradi-tional Chinese medicine ( TCM ) theory . This article summed up documents , clinical studies , basic experimental studies , and modern scientific researches to review the research results of the relationship between heart and emotion . The connotation of heart dominating mind theory in modern biology was interpreted . And the scien-tificity of TCM theory was explained .
3.Advances in the study of precise radiotherapy for non-small-cell lung cancer
Journal of International Oncology 2006;0(10):-
With the development of computer techniques and medical imaging examining methods , precise radiotherapy is becoming the major direction of radiotherapy for tuomors. Both of tumor control probability and normal tissue complication probability are improved with precise radiotherapy. This paper critically review the value of PET-CT and breathing control in precise radiotherapy for non-small-cell lung cancer (NSCLC).
4.Occurrence of Castleman disease secondary to the treatment of solitary plasmacytoma of bone: a case report.
Wen XU ; Yong YU ; Ya-qin ZHI
Chinese Journal of Hematology 2011;32(12):873-873
Bone Neoplasms
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therapy
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Castleman Disease
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etiology
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Humans
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Male
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Middle Aged
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Plasmacytoma
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therapy
7.Evaluation of spatiotemporal image correlation on fetal cardiac systolic function in normal pregnancy
Xu ZHAO ; Ya YANG ; Rongjuan LI
Chongqing Medicine 2013;(25):2961-2963
Objective To investigate the evaluation value of spatiotemporal image correlation (STIC) on fetal cardiac systolic function .Methods The fetal cardiac cycle images were collected by the four-dimensional(4D) STIC ultrasound technique in 160 normal singleton pregnancies .The virtual organ computer-aided analysis(VOCAL) technique was used to measure the ventricular end-systolic volume (VESV) and ventricular end -diastolic volumes(VEDV) .The stroke volume(SV) ,ejection fraction(EF) and cardiac output(CO) were calculated .Results VESV ,VEDV together with SV and CO in normal pregnancy were increased with gestation week increase .EF remained constant with advancing gestational week .VESV ,VEDV ,SV ,CO and EF of right ventricle were all larger than those of the left ventricle .Conclusion The fetal cardiac systolic function in normal pregnancy is increased with gestational age increase ,the right heart systolic function is superior to the left heart .
8. Influence of CYP3A and MDR1 genetic polymorphisms on the pharmacokinetics of ciclosporin A
Journal of International Pharmaceutical Research 2015;42(2):148-151
Ciclosporin A (CsA). an immunosuppressive macrolide antibiotics, is widely applied to prevent rejections after organ transplants. CsA is mainly transported by P-glycoprotein (P-gp) and metabolized by cytochrome P450 (CYP450) 3A.Genetic polymorphisms of CYP3A and MDRl probably influence the expressions and bioactivity of CYP3A and P-gp.and may affect the pharmacokinetics of CsA.This issue summarizes the correlation between genetic polymorphisms of CYP3A and MDRl and the pharmacokinetics of CsA to guide the rational and individualized medication.
9.Anatomical study and special guiding devices design for the operation of upper cervical fixation with Atlas titanium cable
Chinese Journal of Primary Medicine and Pharmacy 2005;0(11):-
Objective To observe morphological character of posterior arch of Atlas and lamina of axis,as well as provide anatomical basis to design special guiding device for the operation of upper cervical posterior fixation with Atlas titanium cable so as to make the operation safe and easy.Methods The posterior arch of Atlas and lami- na of axis were observed and measured in 100 adult dry Atlas and axis specimens,then special guiding devices were designed based on the anatomical data.Results (1)The posterior arch of Atlas was thin with a fan-shape section, whose inner plane descended from back to inside and the lamina of axis was stronger and thicker than posterior arch of Atlas,with a vertical inner plane and a ridge near the lower edge.(2)The special guiding device for posterior arch of Atlas should be designed with a bend head as well that for lamina of axis should be designed with a round head. They were used in 61 operations which became safer and easier.Conclusion The operation of upper cervical posteri- or fixation with Atlas titanium cable would be safer with the help of special guiding devices which were designed based on the anatomical character.
10.Category research of nursing outcomes and indicators of hospitalized patients with coronary disease
Ya YANG ; Xinjuan DAI ; Zhongqin XU
Chinese Journal of Practical Nursing 2015;31(15):1093-1096
Objective To carry on the theoretical research of nursing outcomes and indicators of hospitalized patients with coronary heart diease (CHD).Methods Self-designed questionnaire survey was conducted according to the Nursing Outcomes Classification,and then using it among 14 cardiology nursing experts.Results After experts questionnaire,determined 13 nursing outcomes,63 major indicators and 38 secondary indicators,while eliminated 9 indicators.Conclusion Formation of nursing outcomes and indicators of hospitalized patients with CHD is practical,professional,systemic and simplicity,it can be used as a tool to guide the clinical nursing practice.