1.Research Progress in New Dosage Forms of Anti-tumor Drugs for Pulmonary Administration
Chunqing LU ; Yiping ZHENG ; Ya'nan GAO ; Jingling TANG
China Pharmacist 2018;21(3):493-496
Lung cancer is one of the most common malignancies. Anti-tumor drugs with intravenous administration have systemic adverse effects as well as limited efficacy. Drugs can concentrate in lungs after pulmonary administration,which limits the distribution in the other organs and reduces the side effects of anti-tumor drugs. The paper focused on the recent progress in the studies on new dos-age forms of anti-tumor drugs for pulmonary administration for the therapy of lung cancer,so as to provide reference for the development of anti-tumor drugs for pulmonary administration.
2.Antibiotic resistome in farm animals and their related environments: a review.
Ya'nan WANG ; Yongfei HU ; Baoli ZHU ; Xin'an JIAO ; George F GAO
Chinese Journal of Biotechnology 2018;34(8):1226-1233
Overuse of antibiotics in livestock farming has enriched antibiotic-resistant genes as well as resistant bacteria in farm animals and their related environments. These antibiotic-resistant genes can spread to the natural environments by horizontal gene transfer and even to the food chain, posing a serious threat to the ecological environment, food safety and human health. With the development of genomic technology, the diversity and ecological distribution of antibiotic-resistant genes in farm animals and their related environments have been recently revealed. Here we summarized the research progress on antibiotic resistance genes in related fields, potential influence on human health, and future research needs.