Abstract: Objective To analyze the clinical features and the key point of diagnosis of occupational dental erosion Methods (ODE). Three cases of diagnosis data of occupational diseaseof ODE have been collected to analyze retrospectively. Results - Thethreecaseshadaclearhistoryoflong timeexposuretoacidfogand/oranhydride,andtheirworkingyearsranged from 9.5 to 17.4 years. The mainly clinical manifestation was sclerous tissue damage of anterior tooth in above cases. What′s more, abrasion, wear, external injury, enamel hypoplasia, dental fluorosis, dental caries, wedge defect and other diseases of - dentalscleroustissueswereexcluded,andnon ODEduetoacidicfoods,beverages,drugs,andcertaindiseasescanbeexcluded.- Intwoofthreecases,twoormoreanteriorteethwereidentifiedassecondaryortertiaryaciderosionwhichwassuspected ODE, thereforetheyappliedfortheoccupationaldiseasediagnosisafterfivemonths/eightyears,andthentheywerebothdiagnosedas-ODE(gradeⅡ).Theotheronewasfirstdegreedentaletching,includingtwoteethintheanteriordentalarea,whoprocessedthe-ConclusionoccupationaldiseasediagnosistwoweeksafterbeingsuspectedODEandwasdiagnosedasODE(gradeⅠ).The onsetofODE isinsidious,and theinitialsymptomsarenotobvious,which iseasytobeignored.Thediagnosisand differential diagnosisofODEcanbedistinguishedbasedontheoccupationalexposurehistoryofacidfogand/oranhydride,medicalhistory andclinicalfeatures.