1.Changes of bone mineral density and risk factors analysis of OP in typeⅡdiabetes old female patients
Chinese Journal of Primary Medicine and Pharmacy 2011;18(11):1488-1490
Objective To explore the changes of bone mineral density and risk factors of OP in old female patients with type Ⅱ diabetes.Methods 737 cases of old female patients with type Ⅱ diabetes in Department of Endocrinology were analyzed.All patients were first divided into two groups(Group A,with OP;Group B,without OP)according to OP.Then,the changes of bone mineral density and related risk factors were analyzed with Logistic regression approach.Results In the comparison of Group A and Group B,the results are shown as follows.In Group A:ICTP(7.34±1.84)μg/L,FBG(7.12±1.14)mmol/L,BMI(22.45±2.37)kg/m2,BMD,A(62.45±17.56);InGroup B,the corresponding levels were(4.13±1.07)μg/L,(8.48±1.28)mmol/L,(15.46±6.78)mmol/L,(89.75±14.56)respectively.The resuhs presented statistical differences.(t=29.958、-14.405、16.262、-22.665,both P<0.05).In Group A,HbAle(7.33±0.32)%,serum calcium(2.35±0.72)mmol/L,serum phosphorus(1.03±0.23)mmol/L,the corresponding values in Group B are(7.21±0.24)%,(2.42±0.34)mmol/L,(1.02±0.28)mmol/L.There sxe no statistical differences in two groups(both P>0.05).In Group A,FN(52.50±18.40)pmol/L,UALB was(8.03 ±1.86)mg/L,Leptin was(5.14 ±1.19)μg/L;the Values in Group B were (40.70±16.34)pmol/L,(5.91±1.24)mg/L,(5.63±1.23)μg/L,The values of FN,UALB in both groups had statistical differences(t=7.469、18.515,both P<0.05);the values of Loptin in two groups had no statistical difference(P>0.05).Based on the incidence of OP among old female patients,the leveh of HbAlc,serum calcium,serum phosphorus,ICTP,FBG,BMI、BMD,FN,UALB,Leptin,course of disease,losing body mass,were taken as independent variables and to analyze use Logistic Regression approach.Conclusion FN,UALB,course of disease,BMI and losing body mass were the independent risk factors of OP in old female patients with type Ⅱ diabetes.
2.Influence of modified oxygen supply device on oxygen inhalation effect of patients receiving oxygen therapy
Chinese Journal of Practical Nursing 2011;27(14):10-12
Objective To discuss the effect of the modified structure of oxygen equipment on oxygen inhalation effect of patients receiving oxygen therapy.Methods The structure of oxygen equipment was modified.and 80 patients who required oxygen therapy were divided into the modified group and the non-modified group according to odd and even number of hospital admission sequence randomly with 40 patients in each group.The modified group used the modified oxygen equipment,the non-modified group used traditional one.The differences of respiration,heart rate and blood oxygen saturation rate between the two groups before oxygen inhalation,30 minutes and 2 hours after oxygen were compared.Results There was no significant difference in the respiration,heart rate and blood oxygen saturation rate between the two groups.Conclusions The modified oxygen equipment doesn't affect the oxygen therapy effect of patients,besides,it avoids the problems of pollution and the complicated disinfection procedure of the structure of the humidifier bottle,fluid and breathing vessel of the traditional equipment.
3.The effect of perioperative enteral immunonutrition on liver regeneration function in cirrhotic rats with partial hepatectomy
Yuehua GUO ; Xiaofang YU ; Huiqun YU
Chinese Journal of General Surgery 1993;0(03):-
Objective To evaluate the effect of perioperative enteral immunotrition(IMPACT) on liver regeneration in cirrhotic rats with hepatectomy. Methods Forty-eight cirrhotic rats were randomly divided into two groups: Group A, perioperative standard enteral nutrition group(n=24), receiving standard enteral nutrient NUTRISON during hepatectomy. Group B, perioperative enteral immunonutrition group(n=24), receiving enteral immunonutrient IMPACT after hepatectomy. According to the different time of taking specimens, each group was separated into four subgroups, each subgroup had six rats. The rats in the two groups received equal daily nutritional supplement intragastrically, which was 690kJ/kg per day. Before the 68% hepatectomy, the rats were fed with enteral nutrient for 8 days, and after operation were fed until the day of taking specimens. On the day before hepatectomy and 1st, 4th and 8th postoperative day(POD), MI (mitotic index) of liver cell and PCNA (proliferating cell nuclear antigen) labeling index of hepatocyte were determined. Results MI increased significantly in both group on 4th and 8th postoperative day(P
4.Effect of Acetylcholine on Electric Discharge of Pain-related Neurons in Hippocampal CA1 Area
Yu XIAO ; Xiaofang YANG ; Manying XU ;
Journal of Medical Research 2006;0(03):-
Objective To study the effect of intracerebroventricular(icv) injectionon acetylcholine(ACh) on the elecric activities of pain-related neurons in the hippocampal CA1 area of rat.Methods Trains of the electric impulses applied to the right sciatic nerve were used as noxious stimuli.The discharges of neurons were led out by extracellular recording method with glass microelectrodes.Results Icv injection of ACh(20?g/10?l) caused an decrease of the evoked discharge frequency of pain-excited neurons(PEN) and a prolongation latency as well as an increase of the evoked discharge of pain-inhibited neurons(PIN) and a shortening of inhibitory duration.Conclusion The response of pain-related neurons in hippocampal CA1 area to the noxious stimulation is weakened by icv injection of ACh,exhibiting analgesic effect.
5.The Value of Endoscopic Duodenal Feeding Tube Placement in Severe Coma Patients with Endotracheal Tube by Tracheostomy
Yexiang ZHANG ; Hanxing ZHOU ; Xiaofang YU
Journal of Chinese Physician 2001;0(04):-
Objective To explore the value of endoscopic duodenal feeding tube placement in severe coma patients with endotracheal tube by tracheostomy. Methods 28 patients, who suffered from severe coma with endotracheal tube by tracheostomy, received endoscopic duodenal feeding tube placement. Results Endoscopic duodenal feeding tube placement in all 28 patients was successful, and complications such as tube blocking or dropping occurred only in one patient. The average time of placing duodenal feeding tube was 16 min. Conclusion Endoscopic duodenal feeding tube placement was an effective, simple,convenient and safe way to set up enteral nutrition for severe coma patients with endotracheal tube by tracheostomy.
6.Study on Contact Endoscopic Argon Plasma Coagulation for the Treatment of Protuberant Erosive Gastritis
Yexiang ZHANG ; Hanxing ZHOU ; Xiaofang YU
Journal of Chinese Physician 2001;0(08):-
Objective To evaluate the efficacy and safety of contact endoscopic argon plasma coagulation(APC) for treating protuberant erosive gastritis. Methods 63 patients with protuberant erosive gastritis were randomly divided into groups A and group B, which were treated with non-contact and contact APC, respectively. The efficacy and safety were compared between the two groups. Results There was no significant difference between group A and group B in the efficacy and complication frequency. The curative rates in group A and B were 96.8% and 96.9%, respectively, and only 3 patients had abdominal pain or distension 1 to 3 days after operation, and disappeared within 3 to 7 days after treatment in each group. The numbers of ineffective operation in groups A and B were 284 and 96, respectively. The duration of operation in groups A and B was 11 min and 38 sec,7 min and 22 sec, respectivley. The numbers of accidental injury in group A and B were 137 and 58 times, respectively (all P
7.The application of intraoperative endoscopy during the emergency exploratory laparotomy in the patients with acute massive small intestinal bleeding
Yexiang ZHANG ; Hanxing ZHOU ; Xiaofang YU
Journal of Chinese Physician 2000;0(12):-
Objective To evaluate the application of intraoperative endoscopy during the emergency exploratory laparotomy in the patients with acute massive small intestinal bleeding.Methods Twenty-six patients with acute massive small intestinal bleeding were examined by intraoperative endoscopy during the emergency exploratory laparotomy and the clinical data were analyzed.Results The hemorrhagic reasons were clarified in 25 patients(96.2%) through the application of intraoperative endoscopy.Of the 25 patients,the results showed that 2 cases were with duodenal leiomyoma,1 case duodenal Dieulafoy' disease,5 cases small bowel leiomyoma,2 cases small bowel leiomyosarcoma,2 cases ileum lymphoma,3 cases ileum ulcer,4 cases small bowel cavernous hemangioma,5 cases small bowel arteriovenous dysmorphosis and 1 case pancreaticojejunostomy cut bleeding.The average examination time was 15 min and no complications related to intraoperative endoscopy occurred in all patients.Conclusion The application of intraoperative endoscopy,which may increase the detection rate,is efficient and safe during the emergency exploratory laparotomy in the patients with acute massive small intestinal bleeding.
8.Evaluation on the significance of intraoperative laparoscopic ultrasonography in hepatobiliary surgery
Shiyun BAO ; Xiaofang YU ; Jian SHUAI
Chinese Journal of Digestive Endoscopy 1996;0(05):-
Objective To evaluate the significance of intraoperative laparoscopic ultrasonography (IOUS) during hepatobiliary surgery. Methods Sixty-eight cases of hepatobiliary lithiasis (liver disease 23 and cholecystopathy with difficulty in management by preoperative estimation, 45 ) were examined by intraoperative laparoscopic ultrasonography. Results Two CBD stones and one Mirrizi syndrome were found in IOUS. The laparoscopic procedures were successful fulfilled in 68 cases under the guidance of sonography including fenestration on liver cyst, incision and drainage on liver abscess, resection and biopsy on space occupied liver lesion with unknown cause, resection of solitary space occupied mass in liver, destruction of unre-sectable liver cancer by microwave and injection of absolute alcohol and chemotherapy through portal vein catheterization, cholecystectomy in acute cholecystitis, chronic cholecystitis with chiledolithiasis, and broad pedicle polyps in gallbladder etc. Conclusion IOUS has the advantages of non-invasive, fast, repeatable, high accuracy and has important clinical significance in laparoscopic diagnosis and treatment.
9.Complications following laparoscopic versus open distal pancreatectomy: a meta-analysis
Chaohui ZHEN ; Yan TAN ; Xiaofang YU
Chinese Journal of Hepatobiliary Surgery 2015;21(8):534-539
Objective To systematically evaluate the safety of laparoscopic distal pancreatectomy (LDP) compared with open distal pancreatectomy (ODP).Methods Databases including Cochrane library,MEDLINE,EMbase,Google Scholar and Chinese National Knowledge Infrastructure were searched to enroll randomized clinical trials (RCT),controlled clinical trials (CCT) or retrospective case-control studies to compare LDP with ODP.All articles received quality assessment according to the inclusion and exclusion criteria,then the selected indices were analyzed using the Review Manager Version 5.0 software (The Cochrane Collaboration,Oxford,United Kingdom).Results 21 manuscripts with a total of 2 797 patients were enrolled.1 150 patients underwent LDP and the remaining 1 647 patients underwent ODP.In 20 studies (n =2 597),the total postoperative complication rates were 33.90% for the LDP group versus 46.80% for the ODP group [RR =0.76,95% CI(0.69 ~ 0.84),P < 0.01].In 8 studies (n =1 869) there was no significant difference [RR =0.51,95% CI(0.21 ~ 1.24),P >0.05] in the perioperative mortality between LDP (4/703) and ODP (18/1 166).In 20 studies (n =2 757) there was no significant difference [RR =0.89,95% CI(0.75 ~ 1.06),P > 0.05] in the pancreatic fistula rate between LDP (168/1 132) and ODP (281/1 625).In 11 studies (n =1 840) the wound infection rate of LDP (3.24%) was significantly lower than ODP (10.85%) [RR =0.34,95% CI(0.23 ~ 0.52),P < 0.01].No significance was found between the two groups in the rates of pulmonary complications,peritoneal infection,urinary tract infection,postoperative bleeding,pseudocyst formation,intestinal obstruction and ascites formation between LDP and ODP.Conclusions When compared with the traditional open procedure,LDP has the advantages of significantlylower rates of postoperative complication and wound infection.There were no significant differences in postoperative mortality,and pancreatic fistula rate between LDP and ODP.This meta-analysis suggests that LDP is a safe and feasible operative method.
10.Application of bedside ordinary-probe-guided free-hand percutaneous transhepatic gallbladder drainage in the treatment of severe cholecystitis
Yang CHEN ; Shiyun BAO ; Xiaofang YU
The Journal of Practical Medicine 2015;(11):1818-1820
Objective To evaluate the clinical effectiveness of percutaneous transhepatic gallbladder drainage introduced by bedside ordinary-probe-guidance with free-hand technique in severe cholecystitis. Methods 85 cases treated with the operation were observed and analyzed. Results Infectious bile was successfully drained in all cases without serious complications. 83 cases received satisfactory outcomes. 2 elderly patients died from MODS secondary severe infection. Conclusion Bedside ordinary-probe-guided free-hand percutaneous transhepatic gallbladder drainage is a safe and convenient treatment with minimal invasion for severe cholecystitis, which can be widely used in clinic.