This study was aimed to analyze the influence of specific clinical effect of Dioscorea opposita Thunb. by dosage in order to summarize its rules. Recordings on pills containing D. opposita Thunb. from the classic prescrip-tion of the Formula Dictionary of Traditional Chinese Medicine were collected. Dosage of D. opposita Thunb. was used as the cardinal line. EXcellwas used to conduct schematic analysis. The results showed that small amount of D. opposita Thunb. had the effect of reinforcing the spleen. The effect of tonifying the lung had the dosage boundary line of 10 g. The small dosage had weak effect and large dosage had strong effect. The effect of tonifying the kidney was often the middle dosage. When the dose was larger or smaller, the effect was not obvious. The effect of consoli-dating the kidney was obvious when using larger or smaller dosage. It was concluded that the dosage of D. opposita Thunb. had relatively big influence on its effect, which provided reference of more value for the clinical practice and health cultivation.

OBJECTIVE:To explore a reimbursement mechanism for adverse drug reactions(ADR)suitable to the condition of China.METHODS:Based on the condition in China,we evaluated the feasibility of applying insurance mechanism into ADR reimbursement from aspects of the development of insurance industry and pharmaceutical industry as well as the characteristics of ADR etc.Meanwhile we put forward some suggestions on the construction and operation of the ADR liability insurance.RESULTS & CONCLUSIONS:ADR liability insurance can help guarantee patients' legitimate rights of life health,settle medical disputes,facilitate the development of pharmaceutical industry and promote ADR reporting and management work.To carry out ADR liability insurance,issues like insurance rate,national policy support and evolving of ADR monitor network should be taken into consideration.

Suture was a traditional method for tissue repair. However, sutures used in the closure of surgical wounds can induce inflammation and lead to scarring that appears as crosshatch marks. Threads used for sutures may cause immune response and surgical infection. In this review, we introduce a novel sutureless technique for wound repair, called photochemical tissue bonding (PTB). Absorption of visible light by a photosensitizing dye initiates photochemical reactions leading to covalent protein-protein crosslinks that bridge the wound surfaces, thus producing an immediate seal between the wound surfaces. This technique has been applied in various tissues including skin, cornea, nerve, blood vessels, et al. PTB reduces inflammation resulting in less scarring in skin. PTB dramatically improves the incidences of vascular anastomotic leakage and stricture. In addition, PTB enhances the recovery of nerve function after nerve repair.

This study was aimed to determinate the content of quercetin from different parts (such as flowers, fruits, stems, leaves and branches) of Penthorum chinense Pursh. from Sichuan province so as to offer reference for the comprehensivedeve lopment and utilization of P. chinense Pursh. The quantitative determination of quercetin from five groups of different parts of P. chinense Pursh. were carried out and put into comparison by the reversed-phase high performance liquid chromatography (RP-HPLC). The results showed that there were larger differences of content among different parts. The highest content of the medical parts were flowers and fruits, which was followed by the leaves, stems and branches. It was concluded that different parts (such as flowers, fruits, stems, leaves and branches) of P. chinense Pursh. from Sichuan province should be divided in the clinical and productive practice, which was to supply the scientific basis for enhancing the curative effect and reasonable exploitation and utilization of the resource of P. chinense Pursh.

Objective To investigate the efficacy of procaterol and montelukast on lung function in children with moderate persistent asthma.Methods 86 children with moderate persistent asthma from January 2014 to December 2014 in our hospital were studied,and according to the random number table method,they were divided into the control group and the observation group,43 cases in each group.The observation group was treated with procaterol combined with montelukast,the control group was treated with procaterol.The cough relief and disappearance time,the improvement of pulmonary function after treatment,the clinical effect and the control of asthma after one month of the two groups were compared.Results After treatment,children cough relief and disappeared time of the observation group was significantly shorter than the control group (t =4.418 5,3.784 4,P =0.000 0,0.000 3).After treatment, the pulmonary function was found to improve the situation of the observation group being good than the control group, PEF,FVC,FEV1 ,FEV1 /FVC predicted values were significantly higher than the control group (all P <0.05).The total effective rate of the observation group (93.00%)was significantly higher than 74.40% of the control group (u =2.223 2,P =0.026 2).After one month of treatment,the basic control rate of the observation group(88.37%) was significantly higher than 67.40% of the control group(u =2.386 6,P =0.017 0).The incidence rate of adverse reactions of the observation group (6.98%)was significantly lower than 51.16% of the control group(P <0.05). Conclusion Procaterol combined with montelukast in the treatment of children with moderate persistent bronchial asthma can improve clinical efficacy,safety,and improve symptom control rate,it is worthy of promotion.

To compare the clinical efficacy and safety of atomization inhalation of epinephrine combined with budes-onide and dexamethasone in the treatment of children with acute laryngitis. Methods:Totally 68 cases of children with acute laryngitis were randomly divided into two groups. The two groups were given the conventional therapy, and 30 cases in the control group were giv-en dexamethasone inhalation additionally, and the treatment group was given epinephrine combined with budesonide inhalation addition-ally. The clinical effect in 12, 24 and 72h, clinical symptom disappearance time and adverse reactions in the two groups were ob-served. Results:The clinical effect of the treatment group in 12, 24 and 72h was better than that in the control group. 72h after the treatment, 17 cases in the control group were cured, and the curative rate was 56. 67%, while 27 cases in the treatment group were cured with the curative rate of 71. 05%. The disappearance time of dyspnea and stridor, barking cough, hoarseness and the other clini-cal symptoms in the treatment group was significantly shorter than that in the control group, and the difference was statistically signifi-cant (P<0. 05). The two groups had no obvious adverse reaction. Conclusion:The clinical effect of the combination of epinephrine and budesonide inhalation in the treatment of children with acute laryngitis is better than that of dexamethasone inhalation, and the combination is safe and effective, which is worthy of clinical application.

Objective:To explore the mental health change among college freshmen,taking the age of late 1980,early 1990 and 1995 as the Qividing years.Method:We randomly selected 300 participants (total 900) in each period from the 2006-2015 year coollege freshman newborn psychological assessment data in a university in Xi'an.The data was analyzed by T-test and variance analysis.Results:There were significant differences among gender,family structure and the local institution in both China college students mental health scale (CCMHS) and college students' Psychological Adaptation (CCSAS).The level of mental health and psychological adaptation of college students after 95 is better than the students at the end of 80 and beginning of 90.Conclusion:College students' mental health and psychological adaptation level showed a trend of rising.But it still needs to carry out sexual mental health knowledge lecturer aiming at the existence of psychosexual disorder,continue to strengthen the newborn adaptability education and activities,establish required course of mental health and popularize mental health knowledge.

Anemia ; complications ; Child ; Female ; Fever ; complications ; Humans ; Hypereosinophilic Syndrome ; complications ; diagnosis ; therapy ; Splenomegaly ; complications

memory/attention concentrating factor.Conclusions The intelligence structure of children with LD are imbalance.It is one of important measure to intervene LD early,so as to understand cognitive advantage and feebleness,find out cognitive objection,develop cognitive dominant item,put up education of success,bring along feeble item,and process pertinency training.

A reusable chronocoulometric adenosine triphosphate (ATP)-aptamer sensor was developed in this work.A short chain of DNA marked as cDNA containing complementary sequence was immobilized on gold electrode based on Au-S self-assembly.The ATP aptamer was hybridized with cDNA.The surface-confined DNA could bind with [Ru(NH3)63+ (RuHex) in the electrolyte via electrostatic interaction.Upon target ATP binding, the aptamer confined onto electrode surface was disassociated from the cDNA oligonucleotides into the solution.Such surface density change of DNA lead to the decrease of chronocoulometric signal for the RuHex which confined on the electrode surface.The chronocoulometric signals showed a linear relationship with logrithm of ATP concentration in the range of 1 nmol/L to 100 μmol/L, and the detection limit of this aptamer sensor could reach 0.5 nmol/L (S/N=3).This aptamer sensor could be regenerated 5 times by simple steps.With this aptamer sensor, the basal level of ATP in the brain cortex micorodialysate was determined to be 19.2±3.7 nmol/L (n=3).