Objective:To provide a new idea for the management of drug inspection standards. Methods: The current manage-ment mode for drug inspection standards was analyzed and studied, the problems and difficulties were summarized, and then a novel i-dea and method of electronic management was formulated. Results: The electronic management for drug inspection standards could solve the problems encountered in the traditional management effectively and improve the management efficiency. Conclusion: The standard management information system can provide drug inspection standards in time and ensure the effectiveness, which is very help-ful to the drug inspection.

Pancreaticogastrostomy appears as a method of pancreatic digestive tract reconstruction after pancreaticoduodenectomy.Its research mainly includes incidences of pancreatic-fistula,pancreatic exocrine and endocrine function and methods of pancreaticogastrostomy,which is frequently compared with pancreaticojejunostomy.In this review.The author will discuss these problem and review.The history of pancreaticogastrostomy.

There is a great controversy over the application of corticosteroids in preventing and treating bronchopulmonary dysplasia(BPD).Prenatal use of corticosteroids may reduce the occurrence of BPD.Intravenous corticosteroids within 1 week after birth can reduce the incidence of BPD.However,in light of the short and long-term adverse reactions,it is not recommended.For premature infants with BPD in high risk,clinicians should weigh the pros and cons and may apply a small dose,short course of corticosteroids for intervention in 1 week after birth.Early inhalation or instilling of corticosteroids may be an effective and safe way to reduce the occurrence of BPD.

Objective To study the effect of combined vitamin therapy of B2 and Zhibai-Dihuang Wan on recurrent oral ulcer.Methods A total of 178 patients with recurrent oral ulcer were randomly recruited into a control group and a treatment group.The control group was treated with vitamin B2,0.2g/time,3 times/day;while the treatment group WaS treated with Zhibai-Dihuang Wan,9g/time,twice/day,on the basis of the control group.The therapeutic effects were observed in both groups after 14 days.Results The obvious effective rate in the treatment group was significantly higher than the control group(P=0.0083).while total effective rate did not show significant difierence between the two groups(P=0.0712).The relapse rate in the treatment group was significant lower than the control group.Conclusion It is effective to treat recurrent oral ulcer with the combination of vitamin B2 and Zhibai-Dihuang Wan.

Objective:To enhance the management level of drug emergency inspection. Methods: The emergency inspection of plasticizers was used as the example, and the management in the whole inspection procedures was reviewed to summarize the difficulties and solutions and analyze the management features of drug emergency inspection. Results and Conclusion: There are three keys in successful drug emergency inspection, including correct top-level design, high efficient execution teams and necessary guarantee sys-tems.

Induced pluripotent stem (iPS) cells are reprogrammed by the differentiated adult cells, ard in terms of biological characteristics they are remarkably similar to embryonic stem cells. Compared to the embryonic stem cells, the iPS cells are unrestricted by cell resources, immune rejection and ethics, They maintain the advantages such as specific individual genes, and provide potential cell resources for the fields of regenerative medicine and tissue engineering, This article mainly introduces the iPS cells and their application in the research and treatment of cerebrovascular diseases.

Angiogenesis is a vital biological process. MicroRNAs play important regulatory effects in angiogenesis, and the related research has attracted wide attentioa This article summarizes the latest advances in the regulatory effects of microRNAs in vasculogenesis in recent years, and at the same time, sums up some specific microRNAs in angiogenesis that may have imolved in regulating ischemic diseases.

Neurogenesis refers to a biological process of neural stem cells self-proliferate and differentiate into new neurons, and are integrated into the neural networks, including the embryonic neurogenesis and adult neurogenesis. Studies have suggested that microRNAs (miRNAs) play vital regulatory roles in neurogenesis. This article reviews the molecular mechanisms of miRNAs in the regulation of embryonic and adult neurogenesis as well as the possible regulatory roles of miRNAs in the process of neurogenesis after cerebral ischemia.

Animals ; Liver ; drug effects ; Methylene Chloride ; toxicity ; Mice ; Oxidative Stress

Currently,the most effective treatment for acute ischemic stroke is administration of tissuetype plasminogen activator for intravenous or intra-arterial thrombolysis within 3 to 6 hours after symptoms onset.However,the narrow therapeutic time window and the risk of intracranial hemorrhage have limited its clinical application.Angiogcncsis refers to the process of the formation of new functional blood vessels with the manner of germination from the already existing network of blood vessels.An increasing number of studies have shown that histone deacetylases involve in the regulation of angiogenesis.It may become a potential stroke treatment strategy.This article reviews the role of histone deacetylases in the regulation of angiogenesis.