In order to investigate the feasibility of serum creatine kinase (CK) and blood urea nitrogen (BUN) in monitoring pre-competition training of badminton athletes, the pre-competition training load of 20 badminton athletes was studied, and serum CK and BUN were determined before, immediate and next morning after training. The results showed that after intensive training for one week, serum CK levels were significantly increased by 57.53 mmol/L (P<0.05). After regulation of the training intensity, average serum CK levels were increased by 21.79 mmol/L (P<0.05). BUN contents were increased by 0.83 mmol/L on average with the difference being not significant (P>0.05). After intermittent training, there was significant difference in the average increased levels of serum CK in athletes (P<0.05). There was significant difference before and after regulation of training (P<0.05). The increased levels of BUN were 0.78 mmol/L without significant difference (P>0.05). It was concluded that serum CK was one of the biochemical indicators monitoring the training load sensitivity of badminton athletes, but BUN was of little value in monitoring the training load. Both serum CK and BUN recovered slowly after one-week intensive training and intermittent training, suggesting the metabolic mechanism of human body in training needs further study.

BACKGROUND:Pathogenesis of endometriosis involves many factors that ultimately lead to the emergence of endometrial glands and stroma outside the uterine cavity. OBJECTIVE:To review the research progress in the theory of endometrial stem cel s, and to provide suggestions for the pathogenesis and treatment of endometriosis. METHODS:VIP database and PubMed database were retrieved for articles addressing endometriosis stem cel theory, including original research, experimental analysis, case analysis and review, published from January 2005 to October 2015. Keywords wereendometriosis, stem cel sin Chinese and English, respectively. After removal of repetitive articles, 48 articles were included for final analysis. RESULTS AND CONCLUSION:Endometrial stem/progenitor cel s may exist in the endometrium, and these cel s and bone marrow stem cel s are speculated to be involved in the occurrence of endometriosis. Therefore, treatment of endometriosis is targeted to endometrial stem/progenitor cel s and abnormal regulation on signal transduction pathway, which provides new insight into the mechanism of action and treatment of endometriosis.

Child ; Early Diagnosis ; Evidence-Based Medicine ; Glomerulonephritis ; diagnosis ; therapy ; Glomerulonephritis, Membranous ; diagnosis ; therapy ; Humans ; Kidney Diseases ; diagnosis ; therapy ; Kidney Glomerulus ; pathology ; Nephrosis, Lipoid ; diagnosis ; therapy ; Renal Replacement Therapy

Child ; Glomerulonephritis ; classification ; diagnosis ; therapy ; Humans

Apolipoprotein E (ApoE) has gene polymorphism (ε2,ε3,and ε4).It has been confirmed that ApoE structural and functional abnormlities are closely associated with the hyperlipidemia,formation of atherosclerosis,and its severity,while both hyperlipidemia and atherosclerosis are the risk factors for ischemic stroke.In recent years,although the relationship between the ApoE gene polymorphism and ischemic stroke has been extensively studied,the conclusions are not consistent.This article reviews the correlation studies between the ApoE gene polymorphism and ischernic stroke.

Objective To explore the value of T wave alternans (TWA) in prediction ventricular arrhythmias in post-op TOF children. Methods The characteristics of TWA were retrospectively analyzed in 36 post-op TOF patients and 120 age-matched normal children. The relationship of sustained TWA and ventricular arrhythmias was also analysed. Results Compared with normal children, the incidence of sustained TWA was significantly increased in post-op TOF group (χ2=6.98, P<0.05). In post-op TOF patients, the incidence of ventricular arrhythmia was much higher when sustained TWA was present (χ2=10.41, P<0.05). Conclusions There exists electrophysiological basis for ventricular arrhythmia in post-op TOF children. Sustained TWA has important value in prediction of ventricular arrhythmia of post-op TOF.

The aim of the study was to evaluate the significance of unexplained elevated mater- nal serum alpha-fetoprotein in singleton pregnancies as a prediction of fetal risk. The inclusion criteria for patents with unexplained MSAFP elevations were a MSAFP level 2.0 or greater multiples of the median ( MoM ), a single gestation, a confirmed gestatio- nal age and no fetal malformation or death on ultrasonography. In this study, 991 woman who attended the antenatal clinic at Taejeon Eul Ji Hospital from March, 1996 to March, 1997 were reviewed and data from 79 women with elevated maternal serum alpha-fetoprotein levels were analysed. The 67 of 79 patients with elevated maternal serum alpha-fetoprotein levels had on unexplained elevated MSAFP level. 13 women could not follow up. 54 pregnant women with unexplained elevated MSAFP levels were classified as the index group of singleton pregn- ancy and were matched against a control group. 108 patients with MSAFP levels 0.5 to 2.0 MoM served as control group. The incidence of antepartum hemorrhage ( placental previa ), preterm labor, intrauterine growth retardation ( IUGR ), low birth weight and pregnancy induced hypertension ( PIH ) in two groups was analyzed and the results was subjected to Fisher's Exact Test. None of the patients in the index group had chromosomal abnormalites or birth defect. IUGR occurred in 7 ( 12.96% ) of the index group babies but in only 3 ( 2.78% ) in the control group ( p < 0.02 ). preterm labor occurred in 5 ( 9.26% ) in the index group compared with 2 ( 1.85% ) in the control group ( p < 0.05 ). low birth weight occurred in 3 ( 5.5% ) of the index group babies and in 1 ( 0.9% ) in the control group ( p < 0.1 ). This study suggests that patients with unexplained midtrimester elevations of MSAFP are increased risk for IUGR, preterm labor. But no significance differences were observed in the incidence of low birth weight, antepartum hemorrhage ( placental previa ), PIH.
alpha-Fetoproteins* ; Congenital Abnormalities ; Daejeon ; Female ; Fetal Growth Retardation ; Follow-Up Studies ; Gastroschisis ; Hemorrhage ; Humans ; Hypertension, Pregnancy-Induced ; Incidence ; Infant, Low Birth Weight ; Infant, Newborn ; Obstetric Labor, Premature ; Pregnancy Trimester, Second ; Pregnancy* ; Pregnant Women ; Ultrasonography

Humans ; Proteinuria ; diagnosis ; therapy

Objective To develop a new flow-injection chemiluminescence(FI-CL) method for the determination of omeprazole.Methods Strong chemiluminescence(CL) signal was found generated when omeprazole was injected into the reaction mixture of KMnO4 and luminol.The experimental conditions that affected the CL reaction were optimized by using FI mode.Results Under the optimum experimental conditions(150cm of mixing tubing,0.15mol/L NaOH,7.0?10-5mol/L luminol,2.0?10-5mol/L KMnO4 and 2.8mL/min of flow rate),CL intensity was linearly related to the concentration within the range of 2.0?10-8-1.0?10-5g/mL.The detection limit was 3?10-9g/mL omeprazole,and the relative standard deviations(n=11) were 1.0% and 2.6% for 1.0?10-7g/mL and 1.0?10-6g/mL omeprazole solutions,respectively.Conclusion The proposed method is simple,rapid,sensitive,and suitable for determining omeprazole content in pharmaceutical preparations.

Objective To investigate the effect of being waked up on bispectral index (BIS) and auditory evoked potential index (AEPI) during emergence from propofol administered by TCI.Methods Twenty ASAⅠorⅡpatients aged 31-63 yrs weighing 52-70 kg undergoing elective cholecystectomy using fiberoptic laparoscope under propofol anesthesia administered by TCI were enrolled in the study. During induction of anesthesia the initial target effect-site concentration of propofol was set at 1.0?g?ml-1 and was increased by 1.0?g?ml-1 until 6.0?g?ml-1 step by step. The BIS and AEPI values and hemodynamic variables were recorded at each target effect-site concentration during induction of anesthesia. At the end of operation the infusion of propofol was stopped and the name of the patient was called loudly every minute asking the patient to open his/her eyes. The BIS and AEPI values were recorded 1 minute before and after the eyes opened on command. Results Both BIS and AEPI correlated closely with target effect-site concentration of propofol during induction of anesthesia. During emergence from propofol at the end of operation the BIS value was 69?7 and 72?10 at 1 min before and after the patients opened eyes on command; while the mean AEPI value was 29.8?6.0 and 73.9?5.9 respectively. The increase in AEPI value was significantly larger than the increase in BIS value. Conclusion Both BIS and AEPI correlate closely with target effect-site concentration of propofol during induction of anesthesia. During emergence from propofol the AEPI is more sensitive to being waked up on command.