Objective To provide a help in avoiding accidents related to infusion pump by analyzing its causes and preventive measures. Methods Alarms of infusion pump occurred in 59 patients by infusion pump are reviewed retrospectively and measures to prevent accidents related to infusion pumps are summarized. Results The measures effectually prevent accidents and guarantee patients in using infusion pump. Conclusion The accidents related to infusion pumps can be prevented effectioly by enhancing safety management and making nurses familiar with the infusion pumps,their alarms as well as handling methods.

Objective:To establish an HPLC method for the determination of p-aminophenol in pediatric paracetamol artificial cow-bezoar and chlorphenamine maleate granules. Methods: A CAPCELL PAK MGⅡC18 (150 mm × 4. 6 mm,5 μm) chromatographic column was used with 0. 05% ammonium acetate solution-methyl (85∶ 15) as the mobile phase at the flow rate of 1 ml·min-1 , the detection wavelength was 232nm,the injection volume was 10μl,and the column temperature was 30℃. Results:The linear range of p-aminophenol was 9. 878 4-197. 568 0 ng(r = 0. 999 1), the average recovery was 99. 8%(RSD = 0. 9%,n= 9), and detection limit was 2ng. Conclusion:The method is simple, specific and accurate, which can be used to determine the contents related substances in of pediatric paracetamol artificial cow-bezoar and chlorphenamine maleate granules.

Objective:To ensure the authenticity, scientific and reliability of medical devices clinical trials results.Methods: The drug clinical research institute office set up full-time secondary quality control team, clarified the responsibility, made application form, problem check and track list, subjects’ identity registration form. Using computer network to make 19 medical equipment quality control of clinical trials.Results: Assure the rights and safety of subjects, the validity, accuracy and completeness of clinical trial data and clinical trial results.Conclusion: The drug clinical research institute office, full-time secondary quality control team made strict clinical trial project for the whole process of quality control and ensure the true, scientific and reliable results.

Suppressor of cytokine signaling (SOCS)-3 is a negative regulator of interleukin (IL)-6 signal transduction. The results showed that IL-6 was not only correlated with insulin resistance but also capable to induce the expression of SOCS-3.Thus the high expression of SOCS-3 mRNA may contribute to one of the mechanisms of IL-6 dependent insulin resistance.

OBJECTIVE To prevent nosocomial infection from catheterization room and to reduce the rate of postoperative infection, and improve quality of catheterization room medical care. METHODS Air, object surfaces, the hands of medical staff, and using disinfectant in catheterization room were put to the test every month. RESULTS Totally 253 specimens were put surveillance over three years, total qualified rate was 99.6%, that of air was 98.6% and of object surfaces was 100%, for the hands of medical staff was 100%, and for using disinfectant was 100%. CONCLUSIONS Enhancing prevention nosocomial infection can effectively reduce the infection rate. Surveying the catheterization room termly is an important measure to prevent and control the nosocomial infection.

Gastric cancer is the first in morbidity and mortality among cancers in China. The presence of peritoneal dissemination is the most common cause of recurrence after radical surgery, and has become a pivotal to the curative resection. Whether intraperitoneal chemotherapy can prevent peritoneal dissemination,lymph node metastasis, eradicate invisible seeding tumor cells, reduce peritoneal metastasis, improve survival and quality of life is always under investigation. This review focus on the theory, clinical applications and problems of intraperitoneal chemotherapy for gastric cancer.

AIM: To establish a method for determination of schizandrol A in Mian'er'an Dripping Pills (Semen Ziziphi Spinosae, Fructus Schisandrae, etc.). METHODS: HPLC was used with hypersil C 18 column (250mm?4.6mm; 5?m), methanol water (65∶35) as a mobile phase and detection wavelength at 254nm. The flow rate was 1.0mL?min -1 and at room temperature. RESULTS: The calibration curve was linear (r= 0.9999). The average recovery was 100.2% and RSD was 2.9%, respectively. CONCLUSION: The method is simple, quick and specific, and provides a quality control for the dripping pills.

BACKGROUND:There are two ways to treat the enamel before bracket bonding: etching and sandblasting, but the few studies focus on the direct use of sandblasting technology on untreated enamel surface.
OBJECTIVE:To observe the damage of etchingversus sandblasting to the enamel surface, and to compare the bonding strength of metal brackets adhesive to isolated teeth with these two kinds of surface treatments.
METHODS:(1) Nine premolar teeth removed for orthodontic treatment were randomized into three groups: sandblasting, acid etching and polishing treatment groups. Surface roughening effects of these three kinds of treatments were observed under scanning electron microscope. (1) Another 40 premolar teeth removed for orthodontic treatment were randomized into two groups: sandblasting and acid etching groups. At 24 hours after bracket bonding, the shear strength was detected using mechanical testing machine, and the adhesive residue index of tooth surface was statisticaly calculated.
RESULTS AND CONCLUSION: (1) Under the scanning electron microscope, polishing treatment had no damage to the enamel surface; but in the other two groups, the enamel surface was damaged to varying degrees, especialy in the sandblasting group. (2) The bonding strength in the sandblasting group was significantly higher than that in the acid etching group (P < 0.05), but there was no difference in the adhesive residue index of tooth surface between the two groups (P > 0.05). These findings indicate that compared with the acid etching technology, the sandblasting technology can increase the bonding strength between the enamel and metal bracket, but it also results in more damage.

OBJECTIVE To evaluate the germicidal efficacy of phthalaldehyde disinfectant.METHODS Suspension quantitative bactericidal test was used to observe its bactericidal efficacy and stability.RESULTS The temperature was 20-21℃.The results showed that the average killing rates of Escherichia coli,Staphylococcus aureus and Candida albicans exposed to the solution containing 5 664mg/L phthalaldehyde for 1 min were 99.99%,and the(average) killing rates of spores of Bacillus subtilis var.niger exposed to the solution containing 5 664mg/L(phthalaldehyde) for 60 min and 90 min was 99.94% and 100%,respectively.When its stock solution was stored at 56℃ under airtight condition for 2 weeks,the content of phthalaldehyde decreased by 3.27%.CONCLUSIONS The phthalaldehyde disinfectant is a good and stable bactericide.

Objective To ensure medical safety,standardize the management of medical consumables and guarantee clinical work and scientific research.Methods Various regulations are perfected and specific measures are taken.Results The quality of medical consumables is guaranteed and the hospital infection is avoided.Conclusion The standardization of management can facilitate the safety of medical consumables effectively.