Objective To investigate the incidence and influencing factors for sharp injuries occurred in workers in central sterile supply departments (CSSDs).Methods In October-November 2012,a multicenter cross-sectional survey was conducted,a total of 95 workers in CSSDs of 16 hospitals in Hunan Province were surveyed through questionnaires.Results A total of 89 workers (93.68%)in CSSDs sustained sharp injuries,46 (48.42%)of whom sustained 1 -5 times of sharp injuries,22(23.16%)sustained 6-10 times of sharp injuries,and 11 (11 .58%)sus-tained for at least 10 times of sharp injuries.81 workers (85.26%)sustained at least one time of sharp injuries one year before survey,52 (54.73%)of whom were injured by contaminated needles or other sharps.Logistic regression analysis revealed that higher educational background was protective factor for sharp injuries(OR 90%CI :0.05-0.87);while poor sleep quality(OR 90%CI :1 .03-17.94),frequent touching sharps(OR 90%CI :1 .11 -12.15),and irrational placing of objects by the other medical stuff (surgeons and nurses in operating rooms)(OR 90%CI :1 .23-16.98)were the risk factors for sharp injuries.Conclusion The incidence of sharp injuries among workers in CSSDs is high,which is related to personal factors and environmental factors.It is suggested to strengthen staff training to enhance their awareness of precaution.

AIM:To establish an HPLC method for determining cinnamaldehyde,costunolide and dehydrocostuslactone in the supercritical carbon dioxide extraction of Cinnamomum cassia and Aucklandia lapp.METHODS:The assay was performed on an Agilent HC-C_(18)(150 mm×4.6 mm,5 μm)column by UV detector at the wavelength of 210 nm with acetonitrile-water(gradient elutio)as the mobile phase at the flow rate of 1.0 mL/min,and the column temperature was 30℃.RESULTS:There were good relationships between peak area and sample size of cinnamaldehyde in the range of 148.5-1 732.5 ng,between peak area and sample size of costunolide in the range of 69.42-809.9 ng,and between peak area and sample size of dehydrocostuslactone in the range of 70.32 to 820.4 ng.Average recoveries of them were in turn 99.65%(RSD 0.72%)-99.57%(RSD 1.28%),and 98.90%(RSD 0.81%),respectively.CONCLUSION:The present method is convenient,sensitive and accurate with good reproducibility and can be used for the quality control of the supercritical CO_2 extract of Cinnamomum cassia and Aucklandia lapp.

Objective:To investigate the status quo of redefined disease uncertainty and coping style in hospitalized patients with HBV/ HCV-related liver disease and explore the correlation between them.Methods:A total of 118 patients with HBV/ HCV-related liver disease who were treated in the Second Affiliated Hospital of Xi'an Jiaotong University from May 2018 to November 2018 were investigated by using Self-made General Information Questionnaire, Mishel Uncertainty in Illness Scale Adult and Medical Coping Style Questionnaire. Pearson correlation analysis was used to analyze the relationship between disease uncertainty and coping style.Results:The overall score of redefined disease uncertainty in patients with HBV/ HCV-related liver disease was (88.94±11.48) . The total score of disease uncertainty and the unpredictability dimension were positively correlated with the yield dimension in the coping style questionnaire ( r=0.22, P<0.05; r=0.31, P<0.01) . The complexity dimension, the lack of information dimension and the facing dimension were negatively correlated ( r=-0.32, P<0.01; r=-0.21, P<0.05) . Conclusions:HBV/HCV-related liver disease is a chronic infectious disease, and patients generally have a higher sense of redefinition disease uncertainty. Clinical medical staff should take effective interventions to improve patients' awareness of different stages of the disease, promote patients to form active coping styles and reduce the level of redefined disease uncertainty.