Objective To discuss effect of ESWL with different shock wave frequency for kidney stone on success rate and renal injury. Methods Clinical data of 120 cases treated by ESWL were retrospectivly analyzed. Forty cases were treated by ESWL with 60 times/min. Forty cases were treated by ESWL with 90 times/min. Forty cases were treated by ESWL with 120 times/min. All cases were followed up for 1 months after treatment. Success rate and renal injury degree were analyzed. Results Success rates of 3 groups showed no significant difference (P>0.05). At 1 day after treatment, SCr, BUN of 3 groups increased apparently (P<0.01). And group 120 times/min increased most, next was group 90 times/min (P<0.01). At 14 days after treatment, index recovered as those of before treatment. Conclusion Success rates of ESWL with 60 times/min, 90 times/min and 120 times/min are similar, and renal injury degree in-creased with increasing of shock wave frequency.

Objective To discuss association factors of success rate of ESWL. Methods Clinical data of 340 cases treated by ESWL were retrospectivly analyzed. All cases were followed up for 3 months after treatment. Clinical data and follow-up data were analyzed. Association factors of success rate of ESWL were analyzed. Results Single factor analysis showed that course of disease, stone length, breadth, hematuresis were association factors of success rate of ESWL (P<0.05 or P<0.01). Multiple-factor analysis showed that stone length, hematuresis, breadth were association factors of success rate of ESWL (P<0.05 or P<0.01). Conclusion Association factors of success rate of ESWL are stone length,hematuresis and stone breadth.

Objective:To compare oxytocin combined with ergometrine with oxytocin alone in terms of primary prophylaxis for postpartum hemorrhage (PPH) at the time of cesarean section (CS).Methods:This was a multicenter double-blind randomized controlled interventional study comparing ergometrine combined with oxytocin and oxytocin alone administered at CS. From December 2018 to November 2019, a total of 298 parturients were enrolled in 16 hospitals nationwide. They were randomly divided into experimental group (ergometrine intra-myometrial injection following oxytocin intravenously; 148 cases) and control group (oxytocin intra-myometrial injection following oxytocin intravenously; 150 cases) according to 1∶1 random allocation. The following indexes were compared between the two groups: (1) main index: blood loss 2 hours (h) after delivery; (2) secondary indicators: postpartum blood loss at 6 h and 24 h, placental retention time, incidence of PPH, the proportion of additional use of uterine contraction drugs, hemostatic drugs or other hemostatic measures at 2 h and 24 h after delivery, the proportion requiring blood transfusion, and the proportion of prolonged hospital stay due to poor uterine involution; (3) safety indicators: nausea, vomiting, dizziness and other adverse reactions, and blood pressure at each time point of administration.Results:(1) The blood loss at 2 h after delivery in the experimental group [(402±18) ml] was less than that in the control group [(505±18) ml], and the difference was statistically significant ( P<0.05). (2) The blood loss at 6 h and 24 h after delivery in the experimental group were less than those in the control group, and the differences were statistically significant (all P<0.05). There were no significant differences between the two groups in the incidence of PPH, the proportion of additional use of uterine contraction drugs, hemostatic drugs or other hemostatic measures at 2 h and 24 h after delivery, the proportion requiring blood transfusion, and the proportion of prolonged hospital stay due to poor uterine involution (all P>0.05). (3) Adverse reactions occurred in 2 cases (1.4%, 2/148) in the experimental group and 1 case (0.7%, 1/150) in the control group. There was no significant difference between the two groups ( P>0.05). The systolic blood pressure within 2.0 h and diastolic blood pressure within 1.5 h of drug administration in the experimental group were higher than those in the control group, and the differences were statistically significant ( P<0.05), but the blood pressure of the two groups were in the normal range. Conclusion:The use of ergometrine injection in CS could reduce the amount of PPH, which is safe and feasible.