1.CT features of traumatic bone cyst
Meng LI ; Hanpeng ZHENG ; Xurong WANG ; Qiande QIU
Chinese Journal of Radiology 2013;(6):538-540
Objective To study the CT findings of traumatic bone cyst and to improve the knowledge of that disease.Methods CT features of 8 cases of traumatic bone cyst confirmed by clinical and pathology were reviewed retrospectively.There were 4 females and 4 males,from 26 to 76 years (the median age was 53 years old)of age.Three patients had traffic accidents,2 patients had trauma unrelated,1 patient had boulder crushing,1 had patient stick wounded and 1 patient had high jump wounding.The bone cyst occurred from 18 to 36 months after trauma(2 at 18 months,4 at 24 months,1 at 30 months and 1 case at 36 months).Results There were 6 fractures,1 joint dislocation and 1 frontal soft tissue hematoma in trauma.The cyst located in the ilium of 3 cases,in the calcaneus of 2 cases,in the frontal bone of 1 case,in the hooked bone of 1 case,in the lunate bone of 1 case.The cyst size was 2.0 cm × 2.6 cm to 3.0 cm × 6.0 cm (average 2.7 cm × 4.0 cm).8 cases all single capsule change,all clear boundaries.6 cystic destruction and 2 cystic expansion destruction of bone.Two see separated and 6 no divider of the cyst region.Five bone sclerosis and 3 no hardening of the cyst edge.Three sclerosis and Five no sclerosis of the adjacent bone.Four osteoporosis decalcification and 4 no osteoporosis decalcification of he adjacent bone.Conclusion The traumatic bone cyst is closely related to trauma,CT manifestations with certain characteristics,combined with a history of trauma can make a definite diagnosis.
2.Recent advance in statins in post-stroke epilepsy
Yan LI ; Zhengli DI ; Xurong ZHU
Chinese Journal of Neuromedicine 2020;19(2):211-213
Post-stroke epilepsy (PSE),as one of the common complications after stroke,often seriously affect the quality of life of the survivors.In recent years,more and more studies have found that statins can protect the integrity of blood-brain barrier,alleviate excitotoxic damage of neurotransmitters,reduce neuronal apoptosis,and reduce neuroinflammation,which play a role in brain protection,thereby reducing the risk of PSE.This article reviews the treatment of PSE and application of statins in PSE.
3.Application of rapid induction of intubation by sedatives combined with cis-atracurium in the emergency department
Qiang YANG ; Chao TIAN ; Xurong LI ; Liang MA ; Shuzhen BI ; Jinhua CHEN
Chinese Journal of Primary Medicine and Pharmacy 2020;27(6):724-728
Objective:To study the effect of sedative combined with cis-atracurium in rapid induction intubation in emergency department.Methods:From October 15, 2017 to April 15, 2019, 52 critically ill patients who needed tracheal intubation in emergency department of the People's Hospital of Changzhi were selected.And the patients were numbered according to the time sequence of enrollment, and then randomly divided into group A and group B according to the random number table, with 26 cases in each group.Group A was given sedatives combined with cis-atracurium to induce rapid intubation.Group B only received sedatives to induce intubation.The success rate of intubation, successful intubation time were compared between the two groups.Before and after endotracheal intubation, the heart rate, mean arterial blood pressure, pulse oxygen concentration and the change of catecholamine concentration were compared.Results:The success rate of intubation in group A was 100.0%, which in group B was 76.9%, the difference between the two groups was statistically significant (χ 2=12.15, P<0.05). The time required for successful intubation in group A was (5.2±0.8)s, which in group B was (8.5±2.5)s, the difference was statistically significant (χ 2=6.41, P<0.05). After intubation, the pulse oxygen concentration in group A was significantly increased compared with before intubation ( t=-7.99, P<0.05). After intubation, the heart rate, mean arterial pressure, and serum norepinephrine, dopamine levels in group A were reduced compared with before intubation, but there were no statistically significant differences (all P>0.05). The serum adrenaline level was higher compared with before intubation, but there was no statistically significant difference ( t=-1.03, P>0.05). In group B, the pulse oxygen concentration was significantly increased after intubation compared with before intubation ( t=5.74, P<0.05), but the heart rate, mean arterial pressure, and the change of blood catecholamine concentration levels in group B had no statistically significant differences ( P>0.05). Conclusion:In the airway management of critically ill patients in emergency department, the application of sedatives combined with cis-atracurium to rapidly induce intubation can improve the hypoxia symptoms of patients more rapidly and can keep patients' hemodynamics, catecholamine concentration is relatively stable, it has the characteristics of safety and efficiency.
4.Clinical study on correlative factors of surgery caused infections in pediatric surgery
Jingjie ZHANG ; Shuangshuang LI ; Xurong TANG ; Suirong LI
Chongqing Medicine 2018;47(2):173-176,179
Objective To analyze the factors related to surgical caused infections in children for reducing the infection of operative site.Methods A total of 120 case-times of operation in this hospital were selected.The dynamical air colony number and colony number of surgical instruments were performed the dynamic monitoring.The bacterial colony in air and surface of operative instruments were performed the bacterial species analysis.Results The dynamical air colony number in class 100,1 000,10 000 operating room all presented as "N" character pattern distribution;at 1 h after operation beginning,the variation of air colony number in class 100 operating room was significantly higher than that in class 1 000 and 10 000 operating rooms(P<0.05).The surface colony increase rate of sterile towel wrapped sterile operating instruments was significantly slower than that of the operating instruments directly exposing to air(P<0.05).The surface colony increase rate of operating instruments scrubbed by 1% povidone-iodine was significantly slower than that of operating instruments without scrubbing bloodstain and with scrubbing bloodstain by normal saline(P<0.05).The bacterial species distribution in operating room air was consistent with that in operating instrument surface.Conclusion The operation caused infection in children is significantly correlated with the operating room bacterial colony number and operation time.
5.MicroRNAs and autophagy after cerebral ischemia
Fang HE ; Bin LI ; Wenzhen SHI ; Yu'e YAN ; Xia CHEN ; Lijie GAO ; Nannan HAN ; Huanhuan SHI ; Ning ZHAO ; Xurong ZHU ; Tianzhong WANG ; Ye TIAN
International Journal of Cerebrovascular Diseases 2017;25(11):1053-1056
MicroRNA is a class of short-chain non-coding RNA that regulates gene expression at post-transcriptional level.It can participate in the pathophysiology processes of tumor regulation,neurodegenerative disease,and cardiovascular disease.Recent studies have shown that microRNA can play a reguhtory role in ischemic brain damage through autophagy.This article reviews the effect of microRNA on autophagy after cerebral ischamia and its possible mechanisms.
6.Structural changes of a bacteriophage upon DNA packaging and maturation.
Wenyuan CHEN ; Hao XIAO ; Xurong WANG ; Shuanglin SONG ; Zhen HAN ; Xiaowu LI ; Fan YANG ; Li WANG ; Jingdong SONG ; Hongrong LIU ; Lingpeng CHENG
Protein & Cell 2020;11(5):374-379