OBJECTIVE:To establish a method for the bacterial endotoxin test of ~(131)Ⅰ-epidepride injection.METHO_ DS:After dilution with 10 parts of water,~(131)Ⅰ-epidepride injection was detected with a method of tachypleus amebocyte lysa_te(TAL) and subjected to verification test.RESULTS:The interference of the dilute ~(131)Ⅰ-epidepride injection on TAL can be eliminated after dilution,the bacterial endotoxin levels for 3 batches of 131Ⅰ-epidepride injection were all below 50EU/ml.CONCLUSION:The method for the bacterial endotoxin test of ~(131)Ⅰ-epidepride injection is feasible.

Objective To assess the usefulness of magnification mamography in breast tumor. Methods Both of the mammographic phantom and the breast of 30 cases with breast mass were underwent the magification mammography and the general mammography , to contrast study the shape, margin, calcification , strand of mass in two methods. Results The accuracy rate of diagnosis in 30 cases with benigh and malignant tumor underwent the magnification mammography was 90% , which was greater than that underwent the general mammography. Conclusion The magnification mammography can help to early detect the breast tumor and improve the rate of checkout and dianosis accuracy.

Objective To explore the influence factors of hidden blood loss during the treatment of femoral intertrochanteric fractures with percutaneous compression plate( PCCP) in elder patient. Methods The data of 136 patients with intertrochanteric fracture in our hos-pital from March 2009 to March 2012 treated with percutaneous compression plate were retrospectively analyzed,the effect of age,fracture type,preoperative aspirin,internal diseases on perioperative hidden blood loss, and different haemoglobin ( HGB) levels in patients with dif-ferent distribution were analyzed. Results The mean hidden blood loss volume was 499 mL,which accounted for 92. 54% of the total blood loss. The mean HGB decline was 11 g/L. The rate of on admisson haemoglobin level lower than 80 g/L was 6. 62% in AO type A2. 3 and A3 groups,and the rate of postoperative haemoglobin level lower than 80 g/L was 14. 70%. The average hidden blood loss for AO type A2. 3 (862 mL) and A3 (698 mL) were higher than those for AO types A1 (430 mL),A2. 1 (450 mL) and A2. 2 (415 mL) (P<0. 05). Multi-variate linear regression analysis showed that comminuted fracture and preoperative aspirin treatment were independently associated with in-creased perioperative hidden blood loss. Conclusion It indicated that the overt blood loss was fewer for PCCP operation. Intertrochanteric fracture was the main reason for substantial perioperative hidden blood loss. Types A2. 3 and A3 intertrochanteric fracture were early predic-tive factors of postoperative haemoglobin level lower than 80 g/L in elderly patients.

Objective To investigate the safety of hip arthroplasty during the perioperative period in aged patients with femoral neck fracture .Methods The clinical data in 56 elderly cases of femoral neck fracture treated by hip arthroplasty ,aged more than 65 years old ,were performed the retrospective analysis .Results Among 56 cases ,54 cases hospitalized for 21d[(18-31)d] and suc-cessfully were discharged ,the Harris scores were increased from preoperative 30 (0 -38) to postoperative 83 (72 -91) ,the func-tion of hip joint was obviously improved ;2 cases with the preoperative poor tolerance score died during perioperative period ,there were 3 cases(5 .4% ) of postoperative hip hematoma ,1 cases(1 .79% ) of postoperative hematoma developed secondary bacterial in-fection after puncture and 3 cases (5 .4% ) of postoperative posterior dislocation in the early stage and no case of deep venous thrombosis (DVT) accompanying clinical symptoms .Conclusion Hip arthroplasty is a effective measure for treating aged patients with femoral neck fracture .But those patients with poor operative tolerance should select this operation cautiously

Objective To evaluate the value of 3D printing technology to assist in the repair of severe damage to the radial side hand.Methods From March,2014 to September,2016,there were 9 cases suffered from varying degrees of metacarpal and phalangeal bones injuries with soft tissue destruction at the radial side of the hand.The donor and recipient areas were scanned by 64 row spiral CT before operation.Three dimensional images were obtained by CTA 3D reconstruction technology.Preoperative plan was designed by using Mirror image technology and Virtual surgery aided design technique of Mimics software virtual surgery aided design system.Nine cases were treated with first toe toenail flap with dorsal foot flap combined with second phalangeal bone transplantation to reconstruct thumb and anterolateral thigh perforator flap to repair the wound.The cutting area of the dorsalis pedis flap and anterolateral thigh perforator flaps ranged from 4.0 cm × 5.5 cm to 6.5 cm × 9.5 cm and from 9.5 cm ×17.0 cm to 12.0 cm × 25.5 cm,respectively.Postoperative followed-up was performed to evaluate the effect of the operation.Results All 9 thumbs and flaps survived after the operation.Postoperative followed-up time ranged from 8 to 16 months.The appearance of reconstructed thumb was close to normal,and the two-point discrimination was from 8.0 to 11.0 mm.According to the evaluation criteria of upper limb function of the Chinese Academy of Medical Sciences,7 cases were excellent and 2 cases were good.The survival flaps had soft texture,good blood circulation and satisfactory appearance at the repaired site.Conclusion 3D printing technology assists thumb reconstruction and wound repair for severe damage to the radial side of the hand with good clinical results.