1.Water-soluble non-alkaloid chemical constituents contained in Corydalis yanhusuo by trimethylsilyl derivatization GC-MS.
Zhenhua LIU ; Ruwei WANG ; Houhong HE ; Xunzhi JIANG ; Jianfeng YE ; Su ZENG ; Jiqiang HU
China Journal of Chinese Materia Medica 2012;37(14):2108-2112
OBJECTIVETo study the water-soluble non-alkaloid chemical constituents of Corydalis yanhusuo.
METHODThe 80% alcohol extracts of C. yanhusuo passed through DA201 macroporous resin. Eluted fractions were collected and passed though 732 # cation exchange resin. Water eluate was collected, dried and derived with trimethylsilane. Gas Chromatography/Mass Spectrometry and NIST 2005 library were adopted for MS/MS mass spectrogram to infer the compound structure.
RESULTSixteen compounds were tentatively identified from about fifty peaks detected by GC-MS and identified as hydroxyl and carboxyl polar compounds.
CONCLUSIONThese sixteen compounds were found for the first time in C. yanhusuo. The results provide scientific basis for in-depth development of C. yanhusuo.
Corydalis ; chemistry ; Gas Chromatography-Mass Spectrometry ; methods ; Solubility ; Trimethylsilyl Compounds ; chemistry
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