Primary leptomeningeal lymphoma (PLML) is a rare entity, representing 7% of all cases of primary central nervous system lymphoma and approximately 0.1% of primary central nervous system tumours.1-4 Patients can present with symptoms of raised intracranial pressure, or cranial or spinal polyradiculopathies.1-3 Even with extensive investigations, diagnosis in up to a third of patients can only be confirmed with meningeal biopsy. In this Imaging Highlights, we describe a patient who presented with multiple cranial nerve palsies with corresponding MRI nerve enhancement, and subsequent meningeal biopsy proven lymphoma.

Objective To explore microbic distribution feature of acute rhinitis pafienta' nasal cavity and dependabihty research of respiratory infection.Methods 436 acute rhinitis pafienta were randomly divided tO infection group(314)and non-infection group(122)depended on whether accompanying respiratory infection.Take blenna narium and carry out nasal cavity microbiological detection,meanwhile take blood and mesasure the content of serum IL-4 and IFN-γ.Results The staphylococcus aureus taked the most proportion(58.6%and 3 1.2%)of nasal cavity bacterial distribution in infection group and non-infection group,the following bacterium were the staphylococcus epidermidis(44.9%and 46.7%),bacillus meningitidis purulentae(7.9%and 4.9%)and bacillus coli(3.5%and 1.6%),the major eumycete were the peptostreptococcus asaeeharolyticus(1.9%and 1.6%),eubacterium lentum (1.6%and 0)and eubacterium mucus(0.9%and 0.8%),the major virus were the syncytial virus,the rhinoviru8es,adenodrus,influenza virus,parainfluenze virus and coronaviruses.The respiratory tract infection patients' content of serum IL-4 Were significant higher(P＜0.05)than the non-infection group,but the content ofIFN-γ were signifieanfly reduced(P＜0.05).Conclusion The staphylococcus aureus,syncytial virus,rhinoviruses,adenovirus and influenza virus have the close relation with the infection of the respiratory tract,which can cause the disorder of organism immune function.

Arteries ; Female ; Head ; Humans ; Middle Aged

Biopsy ; CD79 Antigens ; metabolism ; Central Nervous System ; Diagnosis, Differential ; Female ; Humans ; Immunohistochemistry ; Inflammation ; Ki-67 Antigen ; metabolism ; Lymphoma, Large B-Cell, Diffuse ; diagnosis ; Magnetic Resonance Imaging ; Middle Aged ; Panniculitis ; diagnostic imaging ; Prognosis