Objective To observe the protective effect of Weishu Powder(WP) on hepatic injury induced by pentachloronitrobenzene(PCNB).Methods SD rats were randomized into 4 groups: normal group,model group,high-dosage WP group(in the dose of 2.50 g?kg-1 ?d-1) and low-dosage WP group(in the dose of 1.25 g?kg-1 ?d-1).Except the normal group,the other three groups received gastric gavage of PCNB 400 mg?kg-1 ?d-1 for 15 continuous days.After treatment,hepatic index was assayed,serum glutamic-oxalacetic transaminase(GOT) and alkaline phosphatase(ALP) levels and hepatic malondialdehyde(MDA) content were detected,and hepatic pathological examination was also carried out.Results Hepatic index,serum GOT and ALP levels,and hepatic MDA content were increased(P

【Objective】 To investigate the effect of Weishu Powder (WP) on acute liver injury induced by carbon tetrachloride (CCl_4) in mice. 【Methods】 Fifty mice were randomized to normal control group (group A), model group (group B), bifendate pills group (group C), low-dose WP group (group D) and high-dose WP group (group E). The mice in the above groups were fed with the corresponding drugs by gastric infusion for 7 days. On the 8th day of feeding, the mice except those in group A were given 0.5% CCl_4 peanut oil solution (10 mL/kg) by intraperitoneal injection. Sixteen hours later, liver weight, serum level of alanine aminotransferase (ALT), malondialdehyde (MDA) content and necrotic focus amount in the liver were observed. 【Results】 As compared with the normal group, liver weight, serum ALT level and necrotic focus amount were increased in model mice with CCl_4-induced acute liver injury (P

OBJECTIVETo verify the clinical efficacy on rear thigh muscles strain of athletes treated with surrounding needling of electroacupuncture and hot compress of Chinese medicine.

METHODSEighty-six cases were randomly divided into an observation group and a control group, 43 cases in each one. In the observation group, surrounding needling of electroacupuncture and hot compress of Chinese medicine were used at Ashi points around the local affected area of rear thigh muscles. In the control group, conventional needling method and local cupping were applied at Chengfu (BL 36), Yinmen (BL 37), Weizhong (BL 40), etc. The treatment was given once a day. Ten treatments made one session. Two sessions were required. The score of rear thigh muscles pain, swelling and tenderness, walking function recovery and the total score were compared before and after treatment between two groups. The efficacy was compared between two groups.

RESULTSThe score of pain, swelling and tenderness, walking function recovery and the total score were reduced obviously after treatmeat in two groups (all P < 0.01), and the improvements in the observation group were superior to those in the control group (P < 0.01, P < 0.05). The cured and remarkably effective rate was 83.7% (36/43) in the observation group, which was better than 60.5% (26/43) in the control group (P < 0.05).

CONCLUSIONThe efficacy of the surrounding needling of electroacupuncture and the hot compress of Chinese medicine is significant on rear thigh muscles strain for the athletes, which is superior to that of the conventional needling method and cupping in terms of the improvements in the symptoms and physical signs as well as the recovery of the walking function.

Acupuncture Therapy ; Adolescent ; Adult ; Athletes ; Combined Modality Therapy ; Drugs, Chinese Herbal ; therapeutic use ; Electroacupuncture ; Female ; Humans ; Male ; Middle Aged ; Muscle, Skeletal ; physiopathology ; Sprains and Strains ; drug therapy ; physiopathology ; therapy ; Thigh ; injuries ; Treatment Outcome ; Walking ; Young Adult