1.Consensus on diagnosis and treatment of dyslipidemia by TCM (First Draft)
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(08):-
Dyslipidemia is one of metabolic disorder of blood lipids including cholesterol or triglycerides.Based on the close relationship with the atherosclerosis,there is little doubt that hyperlipidemia is the major risk factor for morbidity and mortality of cardiovascular diseases.To control dyslipidemia is one of the most important measures to prevent and cure the cardiovascular diseases.The patients with dyslipidemia will take life-term western medicine.However Chinese medicine does well in treating light and middle grade dyslipidemia,which can reduce development of cardiovascular incidents and adverse reactions of western medicine.This guideline assembled all the experts'experience and expertise from Cardiopathia Committee of China Association of Chinese Medicine,which was also based on nearly thirty-year literature searching about essential hypertension home and abroad.Furthermore,we mainly classif ied TCM syndromes and made treatment principles according to our achievement in the last decade and six expert consensus conferences.This article will introduce such a guideline that we want to gather different opinions and suggestions all over our country in order to improve curative effect in practice.Besides,some information about nursing,prevention and rehabilitation is also discussed for the sake of preventing and reducing essential dyslipidemia and its complications,which is according to the theory of"Preventive Treatment of Disease"of Nei Jing.
2.Ultrasonographic diagnosis of parathyroid gland in secondary hyperparathyroism of uremic patients
Xuezhi ZHAO ; Jianquan ZHANG ;
Academic Journal of Second Military Medical University 1981;0(03):-
Objective: To evaluate the value of high resolution ultrasonography for diagnosis of secondary hyperparathyroism(HPT) in uremia and its relationship with serum parathyroid hormone(PTH). Methods: Ultrasonography was used to examine parathyroid gland and serum PTH, calcium,phosphorus in 55 cases of uremic patients. Results: Totally 64 parathyroid glands in 52 patients(94%) and over 2 glands in 11 cases(20%) were found. The volumes of parathyroid gland was larger and the value of PTH was abviously increased in over 2 glands than in single gland( P
3.Mycophenolate mofetil (MMF) used for treating type Ⅳ lupus nephritis and literature review
Xuezhi ZHAO ; Liming ZHANG ; Changlin MEI
Chinese Journal of Rheumatology 2001;5(3):178-180
Objective To observe about curative effect of MMF on type Ⅳ lupus nephritis and to review the literature about MMF used to treat LN.Method Ten patients with type Ⅳ LN were treated with MMF 1~2 g/d plus prednisone at middle or little dose.Curative duration of these patients was between 6 and 12 months.After 3,6 and 12 months curative effect was observed.Results After treatment proteinurie and systemic lupus activity measurement were decreased gradually.Before and after treatment ANA positive rates were 80% and 30%,anti dsDNA antibody positive rates were 50% and 10%,respectively,and low C3 and C4 was rectified.After treatment renal failure in 3 patients was recovered.During treatment major adverse reactions included gastrointestinal symptoms and herpes zoster.Conclusion MMF has exacttly effect on type Ⅳ LN and low side effect.
4.Visualizational Investigation on Width of Pulse Tracing
Zhiguo ZHANG ; Xin NIU ; Xuezhi YANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(05):-
Objective To study the relationship among the area of transverse section of radial artery, the major axis length of the ellipse with same centroid as transverse section, the maximum centroid displacement in the direction parallel with skin surface in a cardiac cycle and width of pulse tracing. Methods ECG, pressure phygmograms and ultrasound images of transverse section of radial artery of 40 patients with different width of pulse tracing and 20 healthy persons were collected synchronously with a new-type sphymograph. On the basis of images analysis with MATLAB 7.0.1, image characteristics of transverse section of radial artery and centroid motion locus of pulse tracings with different width in a cardiac cycle were observed and analyzed. Results Between pulse tracings with different width, there were significant differences in the area of transverse section of radial artery, the major axis length of the ellipse with same centroid as transverse section and the maximum centroid displacement in the direction parallel with skin surface in a cardiac cycle. Conclusions The mean, maximum and minimum value of the area of transverse section and the major axis length of ellipse and the maximum centroid displacement can be used to discriminate width of pulse tracing.
5.Study on Quality Standard of Naru-3 Cataplasm
Hua ZHANG ; Xin NIU ; Xuezhi YANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(12):-
Objective To establish the quality standard of Naru-3 Cataplasm. Method The contents of Radix aconiti kusnezoffii were determined by UV-vis, and meaconitine was determined by HPLC. Results The linear range of meaconitine was 0.129 5~2.074 0 ?g. The quality standard of Naru-3 Cataplasm was established. Conclusion The method can be used for quality control of Naru-3 Cataplasm.
6.Study on Depression Diagnosis Based on TCM Four Diagnostic and Auxiliary Diagnosis ;System
Shangshang ZHANG ; Xuezhi YANG ; Jian ZHANG ; Tian HAN ; Xin NIU
Chinese Journal of Information on Traditional Chinese Medicine 2015;(5):16-19
Objective Base on the theory of traditional Chinese medicine (TCM), obtained human diagnostic information available for joint syndrome differentiation is integrated based on subjective and objective combined syndrome differentiation, in the form of data expression of TCM four diagnosis, forms multiple information fusion of open platform for TCM diagnosis and treatment, and provides some revelation for promoting the development of depression and treatment technology. Methods Totally 30 depression patients and 30 normal people were selected according to the inclusion criteria. TCM four diagnostic and auxiliary diagnosis instrument was used to collect information of four diagnosis, and the statistical software was used for the analysis on pulse diagnosis, and information features of digitalized tongue and listening diagnosis of patients in depression group and normal group were studied. Results Compared with depression group, pulse frequency, fluency, and heart rate of normal group were a bit higher than depression group, without statistical significance (P>0.05);There was statistical significance among pulse frequency, strength, tightness, and pulse wave velocity between the normal group and depression group (P<0.05). 30 patients had 6 depression syndrome types:heart-gallbladder qi deficiency (8 cases), phlegm-heat attacking internally (6 cases), fire excess from yin deficiency (6 cases), liver depression forming fire (6 cases), intense heart fire (3 cases), and heart-spleen deficiency (3 cases). Conclusion The results of differences in pulse diagram parameters were consistent with the theory of classical TCM pulse theory. The results of differences in pulse wave velocity conform to the modern medical research conclusion. TCM four diagnostic auxiliary diagnosis and treatment technology can realize the dynamic detection of depression patients with four diagnostic information, and establish diagnostic methods for depression based on digitalized four diagnostic auxiliary diagnosis.
7.Treatment of differentiated thyroid carcinoma
Lili ZHANG ; Xuezhi YU ; Rongzhan FU ; He GU ; Jingzhon SUN
Chinese Journal of General Surgery 2000;0(11):-
Objective To study the treatment of differentiated thyroid carcinoma. Method The clinical data and, in partricular, the treatment modalities of 173 cases of differentiated thyroid carcinoma were retrospectively analyzed.Results All of the 173 patients were treated by resection and subsequent endocrine therapy.Different types of operations were selected in accordance with the clinical stages.No perioperative deaths occurred.There were altogether 30 operative complications including nerve injury.Ninety-one patients were followed up for over 5 years and no deaths occurred.Jugular lymphatic metastases occurred in 4 patients, sternum metastases in 2 and lung metastasis in 1.Conclusion Surgical resection and endocrine therapy are highly effective for the treatment of differentiated thyroid carcinoma.
8.Impact of pamidronate disodium on the calcification of vascular smooth muscle cells induced by hyperphosphate
Lei BU ; Xuezhi ZHAO ; Xinyu LI ; Jian ZHANG
Chinese Journal of Nephrology 2010;26(12):920-923
Objective To investigate the protective effect and mechanism of pamidronate disodium on calcification in rat vascular smooth muscle cells (RVSMCs) induced by hyperphosphate.Methods RVSMCs were placed in various culture mediam, including normal phosphate medium (Pi 1.4 mmol/L), high phosphate medium (Pi 4.5 mmol/L), different pamidronate disodium concentrations medium (Pi 4.5 mmol/L+pamidronate disodium 10-5, 10-6, 10-7 mmol/L). Calcium content and cell protein content were quantified by the O-cresolphthalein complexone method and BCA protein assay respectively. Calcification was visualized by yon Kossa staining, and cbfα-1,osteocalcin were quantified by Western blotting. Results After culture for 3 days, calcium content in high phosphate group were much higher than that in control group, and pamidronate disodium groups had a lower calcium content compared with high phosphate group (all P<0.05).Calcium deposit in RVSMCs was greater in high phosphate group, while pamidronate disodium groups revealed obviously decreased deposit (all P<0.05). Protein expression of cbfα-1 and osteocalcin in pamidronate disodium groups was much lower than that in high phosphate group.Conclusion Pamidronate disodium can protect RVSMCs from phosphate-induced calcification in vitro, which may be associated with the blockage of transformation of RVSMCs into osteoblast.
9.A new opinion on detection methods for pulse shape and pulse force
Zhiguo ZHANG ; Xin NIU ; Xuezhi YANG ; Yinchu SI
Journal of Integrative Medicine 2008;6(3):243-8
Pulse shape and pulse force are difficult to detect in pulse taking study. But the application of visualized technology extends the space acquisition of pulse taking information, and it is possible to realize the objective detection of pulse shape and pulse force. Rational research thoughts and strategies could be informed by combining image information and other data, and it is a necessary method in implementing the objective detection of pulse.
10.Combined administration of rhubarb and niatrii sulfas for severe acute pancreatitis
Jun LI ; Hui ZHANG ; Leiming ZHU ; Xuezhi WANG ; Junling DING
Chinese Journal of General Surgery 1997;0(06):-
Objective To discuss the therapeutic effects of rhubarb and natrii sulfas for severe acute(pancreatitis)(SAP).Methods Eighty-three patietns with SAP were randomly divided into treatment group(group A,n=45) and control group(group B,n=38).The 2 groups received the same therapy except that group A received rhubarb and natrii sulfas through nasogastric tube.Results In treatment group(compared) to control group,the clinical symptoms such as abdominal pain and distention were more quickly(relieved),with early return to oral food intake,lesser complications and shorter hospital stay(all with P