In order to explore the effect of hepatocholangiolithiasis on hepatobiiiary system, 160 patients with gallstone were observed by using choledochofiberscope, microscope and electnonic microscope. Damage of bile ducts was found in 84 cases(52.5%) and damage of the liver in 40 cases (25% ) with naked eyes. However, denaturation of hepatocytes occured in nearly all of the cases under microscope. To testify the clinical finding, animal experiments were made in 60 rabbits including infusion of gallstone or silt into bile ducts in groupl, 2, and subacute toxiologic experiment was made by direct injection of gallstone or silt into liver tissue(group3, 4). The results showed that under same condition damage of liver and bile duct caused by gallstone is more severe than that caused by silt. The authers suggest that hepatocholangiolithiasis can damage the hepatobiiiary system no matter whether there is obstruction or not. The harmful substance of gallstones can damage liver tissue directly. So effective therapy should be given as early as possible when the dis-gnosis of hepatocholangiolithiasis is made.

BACKGROUND: The wear resistance and hardness of artificial tooth would affect repairing effects in clinic. However, there is lack of professional standard for resin teeth in China.OBJECTIVE: To provide a theoretic foundation for the choosing of the resin teeth in clinic via comparing the wear resistance and hardness among 7 different resin teeth.DESIGN, TIME AND SETTING: A contrast observation. The experiment was performed at the laboratory of Mechanical Engineering College, Shanghai Jiao Tong University from November 2003 to May 2004.MATERIALS: A total of 7 kinds of different resin teeth were selected, namely, hard multi-layer synthetic resin teeth (A); multi-layer synthetic resin teeth (B); synthetic resin teeth (C); EMDURA resin teeth (D); three-layer synthetic resin teeth (E); optostar four-layer synthetic resin teeth (F); and Cosmo HXL (G).METHODS: The wear test was processed by a pin-plate wear machine. The result was measured by the weight loss through wearing and the surfaces of the wear scar were observed by a scanning electronic microscope (SEM); hardness was measured by Knoop hardness. Meanwhile, the relativity between the hardness and wear resistance of resin teeth was analyzed.MAIN OUTCOME MEASURES: The wear resistance and hardness of resin teeth.RESULTS: According to the weight loss and SEM examination, the wear resistance of the different resin teeth was D>A>G>E>B>F>C; and the hardness of different resin teeth was D>A>G>E>F>B>C. The correlation coefficient between the weight loss and hardness was -0.888 (P < 0.01).CONCLUSION: The variation of the wear resistance of the resin teeth may influenced by their different components, molecular weight and manufacturel methods. There are positive correlation between the hardness and wear resistance of resin teeth.

OBJECTIVE:To raise the price fixing of drugs to a scientific and reasonable level.METHODS:From the view of the whole society,the economic efficiency of newly-developed drugs and original drugs was compared with cost-effec?tiveness analysis.RESULTS&CONCLUSION:Through comparison,the price ranges with economic efficiency of newly-de?veloped drugs would be obtained,which could guide the price fixing.

OBJECTIVE:Using the result of pharmacoeconomic evaluation to instruct the management of drug prices.ME_ THODS:Establishing a reference price and combining economic benefit to decide the price of a drug.RESULTS&CONCLU_ SION:According to the rational value scope,the prices of new drugs can be fixed.A reasonable and timely adjustment of the price can be made.

OBJECTIVE To explore the management methods of sterilization and supply department for the control of hospital infection. METHODS Since 2005, strict infection management system in all aspects by the sterilization and supply department has been taken including renewable medical equipment from recycle to distribution, sterile disposable medical equipment from acceptance to distribution, and the district environment and self-protection of its own staff in the sterilization and supply department and so on. RESULTS Hospital infections had not occurred as a result of sterilized supply for three years. CONCLUSIONS Since strict control and management system is carrying out, measures are effective, and good results have been achieved, which provide important guarantees for effectively controlling infection and medical safety.

OBJECTIVE To effectively control the quantum of bacteria existing in the air of the cleaning section in the disinfecting supply division. METHODS The standards and methods set in the Hospital Disinfecting Sanitation Standard(GB15982-1995) were used. RESULTS Scientific,effective and strict control measures should be implemented to make the quantum of bacteria existing in the air to meet the Environment Standard Type Ⅱ. CONCLUSIONS This article provides the credible data for boosting the pureness of the air of the cleaning section of disinfecting supply division.

OBJECTIVE To investigate the procedures and advantages of whole range quality control of disposable sterile medical appliance. METHODS By analyzing the data concerning whole range quality control of disposable sterile medical appliance from Oct 2002 to Oct 2005 in our hospital to summarize the experiences in this field. RESULTS During the last 3 years, the supply room in our hospital had administrated disposable sterile medical appliance 30 069 000 articles altogether, with the qualification ratio of 100%, and no adverse reaction was found; furthermore, the waste was reduced for no massed articles occurred; the cost accounting was raised and the error ratio during delivery was reduced too, the annual error ratio dropped form 0.003% to 0.00066%. CONCLUSIONS The whole range quality control of disposable sterile medical appliance can raise the administration quality, reduce the waste during delivery, and guarantee the disposable sterile medical appliance being used safely and effectively, also, it can provide accurate and useful data of cost accounting to concerned departments.

OBJECTIVE To analyze occupational harmful factors in department of disinfection and supply and take protective measures in pertinency.METHODS We analyzed every tache of work flow in the course of disinfection and supply,and found out the potential occupational harmful factors.Based on them,the easy and feasible protective measures were proposed.RESULTS There existed many occupational harmful factors in the course of disinfection and supply.Therefore,the working environment and occupational protection among staff should be improved.CONCLUSIONS Analysis on the peril of occupational harmful factors,enforcement of protective consciousness and establishment and implementation of operation rules and protective measures are important steps of occupational safety management for staff in department of disinfection and supply.

OBJECTIVE To analyze the cause of failure of bacteria-killing by autoclave.METHODS Under the process of using the fast-reading bio-indicator to take a routine inspect for the autoclave,while the pressure,the temperature and the time for the bacteria-killing were up to the standard,and the result of the inspection was respectively negative and positive.RESULTS For the sudden malfunction of the exhaust valve,the cold air mass was left in the experimental parcel.Therefore,the result was respectively negative and positive.CONCLUSIONS The more strict examination should be taken for the bacteria-killing tank and the advanced B-D process inquiry-device and the bacteria-killing process inquiry device in the world should be adopted to ensure that the process of bacteria-killing is qualified at all times.

Objective To investigate the clinical therapeutic effect of Xianyimucao capsule on hormone level and menstrual recovery in patients with vaginal bleeding after drug abortion.Methods 102 pregnant women with drug abortion admitted in our hospital from June 2015 to December 2016 were selected and divided into two groups by random number table, the control group was given conventional hemostasis and such symptomatic treatment as anti-infection, the observation group was given Xianyimucao capsule on the basis of control group.The clinical efficacy, the levels of serum hormones and menstrual recovery before and after the treatment of the two groups were compared.Then the safety of two groups were evaluated.Results After 14 days of the treatment, the total effective rate of the observation group was 96.1%, which was significantly higher than 80.4% of the control group (P<0.05).And the serum HCG, P and E2 levels in the two groups after the treatment were significantly lower than those before the treatment (P<0.05);serum hormone levels of the observation group were significantly better than that the control group (P<0.05).Compared with the control group, the menstruation recovery of the observation group was significantly shortened (P<0.05);there was no significant difference of the first menstrual cycle and menstrual volume after the menstruation recovery between the two groups.There was no obvious adverse reaction in the two groups during meditation. Conclusion The application of fresh motherwort capsules in the treatment of vaginal bleeding after drug abortion can stop bleeding rapidly , regulate the body's hormone levels and recover normal menstruation with high safety .