Objective To investigate the clinical effect of rapamycin-eluting vertebral artery stent in the treatment of severe ostial vertebral artery stenosis(OV AS),and to analyze the incidence of postoperative in-stent restenosis(ISR).Methods A total of 96 patients with severe OVAS,who received stenting angioplasty at authors'hospital between November 2020 and May 2022,were retrospectively collected.The patients were divided into the observation group(n=48)and the control group(n=48).For the patients of the observation group implantation of rapamycin-eluting vertebral artery stent was carried out,while for the patients of the control group implantation of peripheral balloon dilatation bare metal stent(BMS)was performed.The perioperative basic data,the incidence of complications during follow-up period,and the postoperative incidence of ISR were compared between the two groups.Results Successful stent implantation was achieved in all patients of both groups.During perioperative period no complications such as transient ischemia attack(TIA),dropping-off or fracture of the stent,vertebral artery or stent-related stroke occurred.No statistically significant differences in the length and the diameter of the implanted stents,in the preoperative vertebral artery stenosis ratio,and in the postoperative residual stenosis ratio existed between the two groups(all P＞0.05).In both groups,the postoperative residual stenosis ratio was＜20％.The patients were followed up for a mean period of(12.33±5.82)months(range of 6-18 months),the incidence of postoperative vertebral artery or stent-related stroke in the observation group and the control group was 0％and 4.17％respectively,the difference between the two groups was not statistically significant(P＞0.05).The improvement of clinical symptoms such as dizziness,vertigo,etc.was observed in 47 patients of the observation group and in 45 patients of the control group,and no recurrent posterior circulation TIA or stent-related thrombotic event occurred.The incidence of postoperative restenosis in the observation group was 10.42％,which was significantly lower than 29.17％in the control group(P＜0.05).Conclusion Rapamycin-eluting vertebral artery stent can safely and effectively treat severe OVAS and reduce the incidence of postoperative ISR.(J Intervent Radiol,2024,33:275-279)

Objective:To investigate the iodine nutrition status of children aged 8 to 10 years old in Nanchang City.Methods:From March 2020 to September 2022, 9 counties (districts, administration bureau) in Nanchang City were selected as monitoring points. Each monitoring point was divided into 5 sampling areas according to the east, west, south, north, and middle directions. One township was selected from each area, and 40 non-boarding children aged 8 to 10 years old (age balanced, half male and half female) from one primary school were selected as survey subjects. Edible salt samples from children's homes, as well as a random urine sample were collected to detect salt iodine and urinary iodine level. The thyroid volume of children was also measured.Results:From 2020 to 2022, a total of 5 400 edible salt samples from children's homes were tested, with a median salt iodine level of 24.13 mg/kg. Among them, there were 5 172 qualified iodized salt samples, 168 unqualified iodized salt samples, and 60 non-iodized salt samples. The coverage rate of iodized salt was 98.89% (5 340/5 400), the qualified rate of iodized salt was 96.85% (5 172/5 340), and the consumption rate of qualified iodized salt was 95.78% (5 172/5 400). A total of 5 400 children's urine samples were tested, with a median urinary iodine level of 210.90 μg/L. A total of 2 662 children were examined for thyroid, of which 4 had thyroid enlargement, with an enlargement rate of 0.15% (4/2 662).Conclusion:The overall iodine nutrition of children aged 8 to 10 years old in Nanchang City is at a super appropriate level, and the thyroid enlargement rate meets the national standard (< 5%).