Objective To explore the influence of late pregnancy complicating uterus myoma on the maternal and fetal out‐comes .Methods A total of 368 patients with late pregnancy complicating uterus myoma were taken as the observation subjects . The influence situation of size ,number and location of uterus myoma on the pregnancy ,delivery ,puerperium and maternal‐fatal out‐comes was analyzed .Results The incidence rate of threatened abortion ,threatened premature delivery ,abnormal fetal position ,pla‐centa praevia and placental abruption in complicating uterus myoma with diameter≥5 cm ,multiple ,intramural and cervial myoma was obviously higher than that in complicating uterus myoma with diameter<5 cm ,single and subserous myoma or submucous my‐oma (P<0 .05) .The cesarean section rate for the uterus myoma with diameter≥5 cm ,multiple and intramural myoma was signifi‐cantly increased (P<0 .05) .The incidence rate of fetal distress ,fetal anomaly ,premature infant ,low birth weight infant ,and neo‐natal asphyxia in uterus myoma with diameter≥5 cm ,multiple ,and intramural myoma was obviously increased(P<0 .05) .Conclu‐sion The late pregnancy complicating large ,multiple and intramural myoma has more obvious adverse reactions on maternal‐fetal prognosis .