1.Investigation and Analysis of the Satisfaction and Confidence of the Students Majoring in Non-medical Interdisciplinary Subject in Our University
Hongyan WU ; Long WANG ; Xiong CHEN ; Minghu CEN ; Xing YANG ; Yan ZHANG ; Lei TANG ; Xuerong RAN ; Jia SUN
China Pharmacy 2017;28(27):3750-3754
OBJECTIVE:To improve the education quality of medical school,so as to provide the excellent human resources for the field of health.METHODS:2011-2014 grades of students majoring in pharmaceutical administration,pharmacy (marketing direction) and other non-medical interdisciplinary subjects were selected from our school to complete the questionnaire which conrained the questions about satisfaction and confidence for the major.The results of investigation were analyzed statistically.RESULTS:Totally 2 668 questionnaires were sent out,and 2 435 were recycled with effective recovery of 91.27%.Half of the students majoring in pharmaceutical administration or pharmacy (marketing) etc.were switched from other majors,and 38.40%(935 number) of the students wanted to change the major.The major of clinical,nursing and anesthesiology were most preferred by the students.Only 15.52% (378 number),26.32% (641 number) of the students thought that the school paid enough attention to them or had a positive attitude to their major,respectively.Students majoring in pharmacy (marketing) and health services administration had the lowest satisfaction about their major and the attention paid by the school (P<0.001).With the growth of grade,the satisfaction of students in various aspects had declined (P<0.001).Only 44.72% (1 089 number),34.25% (834 number) of the students had positive attitude towards the study or were optimistic about the future,respectively.With the growth of the grade,students' satisfaction in all aspects had declined (P<0.001).Compared to other students,freshman had more positive attitude towards the study or were more optimistic about the future (P<0.001).Besides,33.65% (491 number)of the students planning to work immediately after graduation lacked confidence to find a good job.CONCLUSIONS:The lower degree of satisfaction and confidence are found in the students majoring in non-medical interdisciplinary subject in the medical school,and this should be treated seriously by the school.
2.Genome of the Giant Panda Roundworm Illuminates Its Host Shift and Parasitic Adaptation
Xie YUE ; Wang SEN ; Wu SHUANGYANG ; Gao SHENGHAN ; Meng QINGSHU ; Wang CHENGDONG ; Lan JINGCHAO ; Luo LI ; Zhou XUAN ; Xu JING ; Gu XIAOBIN ; He RAN ; Yang ZIJIANG ; Peng XUERONG ; Hu SONGNIAN ; Yang GUANGYOU
Genomics, Proteomics & Bioinformatics 2022;20(2):366-381
Baylisascaris schroederi,a roundworm(ascaridoid)parasite specific to the bamboo-feeding giant panda(Ailuropoda melanoleuca),represents a leading cause of mortality in wild giant panda populations.Here,we present a 293-megabase chromosome-level genome assembly of B.schroederi to infer its biology,including host adaptations.Comparative genomics revealed an evolutionary trajectory accompanied by host-shift events in ascaridoid parasite lineages after host separations,suggesting their potential for transmission and rapid adaptation to new hosts.Genomic and anatomical lines of evidence,including expansion and positive selection of genes related to the cuticle and basal metabolisms,indicate that B.schroederi undergoes specific adaptations to survive in the sharp-edged bamboo-enriched gut of giant pandas by structurally increasing its cuticle thickness and efficiently utilizing host nutrients through gut parasitism.Additionally,we characterized the secretome of B.schroederi and predicted potential drug and vaccine targets for new control strategies.Overall,this genome resource provides new insights into the host adaptation of B.schroederi to the giant panda as well as the host-shift events in ascaridoid parasite lineages.Our findings on the unique biology of B.schroederi will also aid in the development of prevention and treatment measures to protect giant panda populations from roundworm parasitism.