1.CT-guided 125I seed implantation for retroperitoneal lymph node metastases:its technical points
Chuang HE ; Yun LIU ; Li YANG ; Xuequan HUANG
Journal of Interventional Radiology 2015;(6):534-536
Objective To introduce several commonly used puncture techniques for retroperitoneal lymph node metastases in order to provide technical guidance in performing 125I seed implantation therapy. Methods The puncture methods used at authors’ interventional department in performing 125I seed implantation therapy for retroperitoneal lymph node metastases were summarized. Results The commonly used puncture methods included parallel needle puncturing technique , trans-viscera puncturing technique , broadening path puncturing technique and coaxial needle puncturing technique. Conclusion An effective combination use of various puncturing techniques to uniformly implant the radioactive 125I seeds into the lesion can improve the therapeutic result and reduce the occurrence of complications.
2.Clinical implication of anastomosed vascular or nenrovascular mini-muscle transfer: an experimental study
Weiqing HUANG ; Xuequan FANG ; Chunhu WANG ; Bairong FANG ; Qun QIAO
Chinese Journal of Medical Aesthetics and Cosmetology 2008;14(4):236-239
Objective To investigate the functional changes of anastomosed vascular or neurovascular mini-muscle transfer and to provide experimental data to clinical application. Methods 32 New Zealand rabbits were operated on by anastomosed neurovascular mini-muscle transfer. In group A, 16 rabbits accepted the anastomosed vascular mini-muscle transfer. In group B, 16 rabbits accepted the anastomosed neurovascular mini-muscle transfer. The electromyography was measured 2 months and 3 months after operation. Results The amplitude of electrical muscle graph (EMG) data in the group A was (2.02±0.41)mV 2 months after operation, and (1.73±0.18) mV 3 months after operation. The EMG data in the group B was (3.90±0.52) mV 2 months after operation and (3.35±0.86) mV 3months after opera-tion. The difference between the two groups was significant (P<0.01). The EMG of anastomosed neu-rovasular mini-muscle transfer was significantly greater than that of anastomosed vasular transfer only.There was no significant difference in latent period of EMG between the two groups (P>0.05). Conclu-sions The muscle functional recovery of anastomosed neurovascular mini-muscle transfer is significant with less demage and no secondary deformity. The results suggest that this technique is worthy to apply for treating facial paralysis.
3.Clinical value of CT-guided percutaneous biopsy of peritoneum in diagnosis of patients with unknown ascites
Liangshan LI ; Li YANG ; Yang LI ; Chuang HE ; Xuequan HUANG
Journal of Regional Anatomy and Operative Surgery 2017;26(3):201-203
Objective To investigate the diagnostic value of CT-guided percutaneous biopsy of peritoneum for unknown ascites.Methods The clinical data of 106 cases of unknown peritoneum in our hospital were collected retrospectively over the past five years (May 23,2011 to August 2,2016).The sensitivity and specificity of the percutaneous biopsy of peritoneum in diagnosis of the patients with unknown etiological ascites were evaluated.Complications were collected to evaluate the safety.Results The 106 patients with unknown ascites were performed with CT-guided percutaneous biopsy of peritoneum.The diagnoses of 91 patients were confirmed pathologically,accounted for 85.85% of the total.Among the 91 patients,there were 60 cases (56.60%) of malignant and 31 cases (29.25%) of benign.The other 15 patients had no clinical diagnosis,which accounted for 14.15% of the total.The diagnostic sensitivity and specificity was 88.35% and 100% respectively,which were significantly superior to cytological examination,biochemical markers and other routine analysis.No severe complications were observed in all patients.Conclusion CT-guided percutaneous biopsy of peritoneum for unknown ascites plays an important instructive role in diagnosis with high accuracy,and it is a safe and effective method.
4.Nursing Experience of CT-guided Iodine-125 Seeds Implantation Brachytherapy for Malignant Tumor
Min TAN ; Xuequan HUANG ; Yong LIU ; Fengxiu LIU
Chinese Medical Equipment Journal 2003;0(10):-
Objective To investigate nursing methods of CT -guided 125I seeds implantation brachytherapy for malignant tumor. Methods Nursing methods in 236 cases of 125I seed implantation therapy were summarized. Results Perfect preoperative examination,and psychological intervention could significantly improve patients mental state. Observation distribution of particles and postoperative observation could promote patients postoperative recovery. Conclusion Preopertive and postopertive nursing and radiation protection is an important factor for 125I implantation brachytherapy
5.A preliminary study of CT 3-D reconstruction of head and neck region of the first Chinese visible human
Xueli PANG ; Xuequan HUANG ; Hong XIAO ; Shaoxiang ZHANG ;
Journal of Third Military Medical University 2003;0(07):-
Objective To obtain the CT image 3 D reconstruction of head and neck region of the first Chinese visible human. Methods The CT data of head and neck region of the first Chinese visible human were processed with Siemens 3 D Virtuoso VA(R2.6) software in SGI Graphics Computer Workstation. The 3 D reconstruction of head and neck surface and skeletal structure were carried out and studied. Results The face and neck were well reconstructed. The nose, lips, ears and chin could be clearly shown. The skeletal structures in the head and neck region were fairly reconstructed and displayed very well and even the fine structures in skull base such as foraman ovale and foramen spinosum could be seen. Many anatomic structures such as pituitary gland, brain stem, cervical marrow, sphenoid sinus, nasopharynx could be displayed in detail on the 3 D reconstruction section. Conclusion This study has realized the CT image 3 D reconstruction and visualization of head and neck region of the first Chinese visible human and provided morphologic data for further studies of 3 D structures, comparative studies of anatomy and imaging of the head and neck.
6.Clinical value of CT guided transthoracic core needle biopsy in diagnosis of pulmonary peripheral lesions
Jiehui ZHU ; Xuequan HUANG ; Haitao LI ; Wei CHEN ;
Journal of Third Military Medical University 2003;0(14):-
Objective To assess the clinical diagnostic value of CT guided transthoracic core needle biopsy (TNB) in patients with pulmonary peripheral lesions. Methods The pathological findings, follow up results, mass size, complications due to paracentesis, and other examination results in 223 patients with pulmonary peripheral lesions undergoing TNB were analyzed retrospectively. Results The positive predictive value of malignant lesions was 100%. False negative was found in 3 cases. There was no false positive of malignant lesions in all the cases. The sensitivity and specificity were 93.6% and 100%, respectively. The negative predictive value of benign lesions was 94.8%. There was no significant difference in the satisfaction rate of multiple biopsy between the large and small nodules. The satisfaction rate of a single biopsy of the large nodule was significantly better than that of the small nodule ( P
7.The hemangioma of alimentary tract
Zulin CHEN ; Xuequan HUANG ; Zhitang SHAN ; Yunsheng LUO ; Deshan GAO ;
Chinese Journal of General Surgery 1994;0(05):-
Eighteen patients with hemangioma of alimentary tract were treated in our hospital from 1980 to 1994 There were 11 males and 7 females,with average age of 48?18 years (ranged from 19 to 76 years) Of them,14 patients were treated with operation,2 with hemangioma of rectum were treated with ligation with snare.All of the 16 patients were cured. The etiology,pathology,diagnosis and management are discussed in this paper The experiences of finding small hemangiomas of jejunum and ileum during operation are also introduced in the paper
8.Pneumorrhagia and pneumothorax occurring after CT-guided cutting needle biopsy for pulmonary solid nodules: a multivariate analysis
Chuang HE ; Yang LI ; Li YANG ; Tingyuan LI ; Liangshan LI ; Shuang WEN ; Xuequan HUANG
Journal of Interventional Radiology 2017;26(7):654-659
Objective To investigate the risk factors of pneumorrhagia and pneumothorax occurring after CT-guided cutting needle biopsy for pulmonary solid nodules.Methods The clinical data and imaging materials of 320 patients with pulmonary solid nodule (≤3 cm),who received 16 G semi-automatic cutting needle biopsy,were retrospectively analyzed.Both univariate and multivariate logistic regression analysis methods were used to evaluate the risk factors of pneumorrhagia and pneumothorax.Results The incidence of needle track hemorrhage was 33.1% and the incidence of pneumothorax was 18.1%,the diagnostic accuracy for benign and malignant nodules was 99.6%.Needle track length was an independent risk factor for pneumorrhagia;every increase of 3 cm in needle track length,the risk of pneumorrhagia would increase 3.881 times,besides,the risk of pneumorrhagia had a parallel relationship with the time used for puncturing (P=0.061) as well as with the number of pleural puncturing (P=0.062).The age,lesion's location and needle-pleural angle were independent risk factors for pneumothorax.Each increase of 10 years in age,the risk of pneumothorax would increase 2.102 times.The pneumothorax risk of pulmonary lesion located at upper lung lobe was strikingly lower than that of pulmonary lesion located at lower lung lobe.Each increase of 20 degrees in needle-pleural angle,the risk of pneumothorax would increase 2.413 times.Emphysema was excluded from the equation because it had only a minute difference (P=0.086).Based on the pneumorrhagia and pneumothorax probability values,ROC curves of pneumorrhagia and pneumothorax were drawn,and AUC values of pneumorrhagia and pneumothorax were 0.753 and 0.725 respectively.Conclusion The occurrences of pneumorrhagia and pneumothorax after CT-guided cutting needle biopsy for pulmonary solid nodules are affected by many factors.Careful preoperative evaluation and skilled intraoperative manipulation can effectively reduce the incidence of pneumorrhagia and pneumothorax.
9.Differences in dosimetric parameters between 125I seed implantation with degradable catheters and free-hand
Yun LIU ; Chuang HE ; Qinghua LIANG ; Yuxiao CHEN ; Liangshan LI ; Jing YUAN ; Tingyuan LI ; Xuequan HUANG
Chinese Journal of Radiological Medicine and Protection 2021;41(1):62-65
Objective:To compare the differences in dosimetric parameters of target areas between 125I seed implantation with degradable catheters and by hand under the assistance of a real-time intraoperative treatment planning system (TPS). Methods:Forty-two simulated lesions were divided into a degradable catheter group and a free-hand group, with twenty-one lesions in each group. 125I seeds were implanted according to the TPS.The pre-plan and post-implant dosimetric parameters were collected, including the minimum dose ( Dmin), maximum dose ( Dmax), mean dose ( Dmean), conformal index (CI), external index (EI), homogeneity index (HI), minimum prescription dose delivered to 90% of the target volume ( D90), and the mean percentage of volume receiving 90% of the prescription doses ( V90). The Bland-Altman method was employed to analyze the consistency of pre-plan and post-implant dosimetric parameters and the Wilcoxon rank-sum test was used for the comparison of the two groups. Results:According to the Bland-Altman analysis, the dosimetric parameters of the two groups were all in agreement before and after seed implantation except for the Dmin and V90 of the free-hand group.Furthermore, the degradable catheter group had smaller error ranges of Dmax ( Z=-3.824, P<0.005), CI ( Z=-1.962, P<0.005), HI ( Z=-2.352, P<0.005), D90 ( Z=-2.453, P<0.005), and V90 ( Z=-3.159, P<0.005). Conclusions:The dosimetric parameters of 125I seed implantation with degradable catheters under the assistance of real-time TPS have good pre-plan and post-implant consistency and smaller error ranges.
10.Skills and the clinical application of CT guided radioactive seed 125I implantation in treating multiple lung metastatic masses.
Wei LI ; Gang DAN ; Jianqing JIANG ; Lie YANG ; Xuequan HUANG
Chinese Journal of Lung Cancer 2010;13(3):230-233
BACKGROUND AND OBJECTIVE125I seed implantation treatment of pulmonary metastases, often because of complicated structure of the chest, was considered as restricted areas. The aim of this study is to evaluate the effectiveness of CT guided radioactive 125I seed implantation in treating lung metastatic tumors.
METHODSTotally 115 metastatic masses were found in 30 patients with CT guiding. 125I seeds were implanted into lung metastatic masses. The approach of implantation was determined according to the location of the lesions (hilar masses, peripheral masses and masses covered by skeletal thorax). The therapeutic effects were evaluated by CT.
RESULTSUniform distribution were achieved by single puncture in 84.3% of patients. The rest patients (15.7%) were received replanting. The follow-up period was 6-24 months (mean 14.6). Among 115 lesions in 30 cases, complete response (CR) was achieved in 80 nodes, partial response (PR) in 20 nodes, No change (NC) in 8 nodes and progressive disease (PD) in 7 nodes. The total response rate was 86.9%. The one-year local control rate were 93.9% (108/115). No severe perioperative complications occurred.
CONCLUSIONCT guided radioactive seed 125I implantation is a safe and effective procedure in treating multiple lung metastatic tumor with minimal invasion.
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Iodine Radioisotopes ; therapeutic use ; Lung Neoplasms ; diagnostic imaging ; radiotherapy ; secondary ; Male ; Middle Aged ; Retrospective Studies ; Tomography, X-Ray Computed ; Treatment Outcome