Objective To explore the clinical effect of enhanced recovery after surgery and pain management during the perioperative period in rectal cancer patients.Methods 100 rectal cancer patients after radical resection were divided into ERAS group (50 cases) and routine care group (50 cases).Results Compare with the routine group,the time of ERAS group was shorter in postoperative bowel function recovery [(1.8 ± 0.6) d vs.(3.4 ± 0.6) d,t =-8.1,P ＜ 0.001],oral feeding [(1.3 ± 0.6) d vs.(3.2 ± 0.6) d,t =-10.1,P ＜ 0.001],intraperitoneal catheter drain [(3.6 ± 0.7) d vs.(5.3 ±0.8) d,t=-6.7,P＜0.001] and mobilization[(1.1 ±0.3)d vs.(2.7 ±0.5) d,t=-12.7,P＜0.001].ERAS group was associated with shorter hospital stay [(4.6 ± 0.6) d vs.(6.1 ± 0.6) d,t =-7.7,P ＜ 0.001],lower costs (P =0.014),lower pain score at the time of 6 h,12 h,24 h and 48 h after surgery (P ＜0.001).There was no significant statistical difference in postoperative complication rate 8％ and 10％ (P =1.000).Conclusions ERAS management in rectal cancer patients after radical operation enhanced postoperative recovery.

To research and design a new type of distal radial artery puncture compression hemostatic device,to solve the problem of distal radial artery puncture and compression hemostat that has not been clinically applied in China.The hemostatic device was mainly composed of hemostatic part,pressure regulating part,fixing part and visual window.The hemostatic device can accurately compress the puncture point,and it was convenient for medical staff to observe the wound through the visual window,find out abnormal conditions such as bleeding or hematoma in time,and take measures to deal with them,which greatly improved the hemostatic effect and comfort of the postoperative puncture point.The new hemostatic device has the advantages of reasonable design and simple clinical operation,which is worthy of clinical promotion.

Telecare technology has facilitated the close integration of information technology and healthcare services. Currently, telecare technology is widely used in different fields to assist caregivers in the behavioural management and monitoring of medication adherence in post-PCI patients, to safeguard therapeutic outcomes and to reduce the incidence of adverse events. This article mainly reviewed the different telecare intervention models for medication adherence in post-PCI patients in China and abroad, the effect of telecare in medication adherence management, as well as shortcomings and prospects. The aim of this review was to understand the current status of the application of telecare in the management of medication adherence in post-PCI patients and to provide new ideas to improve the management of medication adherence in post-PCI patients.

Objective To develop an arm support used for bilateral puncture during trans-radial coronary intervention (TRI) and to explore its effects. Methods The arm support used for bilateral radial artery puncture was designed and developed. Totally 100 patients who received TRI in the Cardiac Catheterization Room of Peking Union Medical College Hospital between May and June 2017 were selected and equally divided into an observation group and a control group according to the random number table. Patients in the observation group were served with the new arm support to reveal the points for radial artery puncture, while patients in the control group used the conventional wooden arm support. The effect of puncture was compared between the patients in the two groups. Results The time used for preparation before radial artery puncture was (1.58±0.56) min and the time need for puncturing and placing sheathing canal in the radial artery was (3.51±0.44) min in the patients in the observation group, both shorter than those of the patients in the control group (t=9.511, 8.740; P<0.05). Totally 96% of the patients felt comfortable with the new arm support, and the operation experience satisfaction in 80% of the doctors was excellent, both higher than those of the patients in the control group. Conclusions The performance of this new arm support for bilateral radial artery puncture is stable and reliable. Compared with conventional methods, the time used for preparation before radial artery puncture is shortened for nurses, and the time needed for puncturing and placing sheathing canal in the radial artery is shortened for doctors. The patients feel more comfortable when using this new arm support, and the doctors have a higher experience satisfaction. The new arm support is convenient and flexible for use, and may be used and promoted in cardiac catheterization rooms.

Objective To explore the effects of dietary intervention before selective coronary intervention on patients with type 2 diabetes mellitus and to provide reference and basis for building a feasible and practical preoperative dietary management system. Methods Totally 300 patients with type 2 diabetes mellitus who received coronary intervention in the Cardiac Catheterization Room of Peking Union Medical College Hospital from December 2016 to December 2017 were selected by convenient sampling and divided into the control group (n=150) and the observation group (n=150) according to the random number table. Patients in the control group were fasted for solids and liquids for 4 hours before coronary intervention, while patients in the observation group received foods and drinks for diabetic patients rather than being fasted for solids and liquids as well as individualized dietary guidance from dieticians, specialized diabetes nurses and intervention nurses jointly. The incidence rate of perioperative hypoglycemia. hunger, thirst, anxiety score before and after the intervention, comfort of dietary management were evaluated between the two groups. Results The control group scored higher in hunger, thirst and anxiety than the observation group (P＜0.05);the comfort of dietary management was higher in the observation group than in the control group (P＜ 0.05);the incidence rate of perioperative asymptomatic hypoglycemia in the observation group was 2.0%, while that in the control group was 20.6%;the incidence rate of perioperative symptomatic hypoglycemia in the observation group was 0, while that in the control group was 1.3%. Conclusions Patients with type 2 diabetes mellitus should not be fasted for solids and liquids as conventionally did before selective coronary intervention. Rather, a scientific preoperative dietary management model can prevent the incidence of perioperative hypoglycemia in patients with type 2 diabetes mellitus, enhancing the comfort and safety of operation during the perioperative period.

Objective:To investigate the current situation of critical thinking ability of nurses in Catheterization Room in China, and analyze its influencing factors, so as to provide reference for improving the critical thinking ability of nurses in Catheterization Room.Methods:In July 2020, the catheterization nurses from 154 hospitals, including Class Ⅲ Grade A, Class Ⅲ Grade B and Class Ⅱ Grade A, in 28 provincial capital cities of China were investigated with general information questionnaire and Chinese Critical Thinking Disposition Inventory (CTDI-CV) , by convenience sampling method. 422 questionnaires were collected in this survey, 408 were valid, and the effective rate was 96.68%.Results:The total score of critical thinking ability of the 408 catheterization nurses was (247.92±33.77) , which was at a low level as a whole. There were 361 nurses (88.48%) without positive critical thinking, 42 (10.29%) with positive critical thinking, and 5 (1.23%) with strong positive critical thinking. Binary Logistic regression analysis showed that nurse level, education background, professional title and position were the main influencing factors of critical thinking ability of nurses in Catheterization Room ( P<0.05) . Conclusions:The critical thinking attitude of nurses in Catheterization Room is generally negative, which is far from positive, and needs to be further improved. The nursing department should give more tendentious policies and support to the nurses in the Catheterization Room. At the same time, the nursing managers in the Catheterization Room should actively take measures to improve the critical thinking ability of nurses.

Objective:To compare the value of contrast-enhanced ultrasound (CEUS) and microangiography (SMI) in differential diagnosis of benign and malignant renal tumors.Methods:CEUS and SMI images of 241 patients with renal tumors (221 malignant tumors and 20 benign tumors) confirmed by surgery and pathology were retrospectively analyzed. The consistency of the two methods for the differential diagnosis of benign and malignant renal tumors with pathological diagnosis was analyzed. Receiver operating characteristic (ROC) curve was used to compare the diagnostic efficacy of the two methods.Results:In CEUS, the main manifestations of renal malignant tumors were fast forward (155 cases, 70.1%), fast regression (194 cases, 87.8%), and high enhancement (181 cases, 81.9%), while the main manifestations of renal benign tumors were slow progression (11 cases, 55.0%), slow regression (9 cases, 45.0%), and low enhancement (14 cases, 70.0%). There were statistically significant differences in perfusion mode, enhancement degree and regression mode between the two groups ( P<0.001). According to diagnostic criteria of CEUS, 224 cases were diagnosed as malignant tumor and 17 cases as benign tumor, the consistency with the pathological diagnosis was moderate ( Kappa=0.62, P=0.581). In SMI, the Adler grade of renal malignant tumor was mainly 2-3 (196 cases, 88.7%), while the Adler grade of renal benign tumor was mainly 0-1 (18 cases, 90.0%), the difference was statistically significant ( P<0.001). According to the diagnostic criteria of SMI, 215 cases were diagnosed as malignant tumors and 26 cases as benign tumors, which were moderately consistent with pathological diagnosis ( Kappa=0.57, P=0.238). The areas under ROC curve of CEUS and SMI for benign and malignant renal tumors were 0.789 and 0.823, respectively, without statistical significance ( P=0.711). Conclusion:CEUS and SMI have different advantages in the diagnosis of renal tumors. SMI is a simple, non-invasive and inexpensive and effective method for the diagnosis of renal tumors.

Objective:To compare the value of contrast-enhanced ultrasound (CEUS) and microangiography (SMI) in differential diagnosis of benign and malignant renal tumors.Methods:CEUS and SMI images of 241 patients with renal tumors (221 malignant tumors and 20 benign tumors) confirmed by surgery and pathology were retrospectively analyzed. The consistency of the two methods for the differential diagnosis of benign and malignant renal tumors with pathological diagnosis was analyzed. Receiver operating characteristic (ROC) curve was used to compare the diagnostic efficacy of the two methods.Results:In CEUS, the main manifestations of renal malignant tumors were fast forward (155 cases, 70.1%), fast regression (194 cases, 87.8%), and high enhancement (181 cases, 81.9%), while the main manifestations of renal benign tumors were slow progression (11 cases, 55.0%), slow regression (9 cases, 45.0%), and low enhancement (14 cases, 70.0%). There were statistically significant differences in perfusion mode, enhancement degree and regression mode between the two groups ( P<0.001). According to diagnostic criteria of CEUS, 224 cases were diagnosed as malignant tumor and 17 cases as benign tumor, the consistency with the pathological diagnosis was moderate ( Kappa=0.62, P=0.581). In SMI, the Adler grade of renal malignant tumor was mainly 2-3 (196 cases, 88.7%), while the Adler grade of renal benign tumor was mainly 0-1 (18 cases, 90.0%), the difference was statistically significant ( P<0.001). According to the diagnostic criteria of SMI, 215 cases were diagnosed as malignant tumors and 26 cases as benign tumors, which were moderately consistent with pathological diagnosis ( Kappa=0.57, P=0.238). The areas under ROC curve of CEUS and SMI for benign and malignant renal tumors were 0.789 and 0.823, respectively, without statistical significance ( P=0.711). Conclusion:CEUS and SMI have different advantages in the diagnosis of renal tumors. SMI is a simple, non-invasive and inexpensive and effective method for the diagnosis of renal tumors.

In this study, we cloned the complete sequence coding for aminoacids in protein (CDS) of goat ST13 gene, analyzed the bioinformation of it, and explored the expression pattern in different goat tissues and goat subcutaneous preadipocytes at different differentiation stages. To be specific, ST13 gene was cloned by reverse transcription PCR (RT-PCR), and the bioinformation was analyzed by online tools or software. The expression in various goat tissues and subcutaneous preadipocytes at different differentiation stages was detected by quantitative reverse transcription PCR (qRT-PCR). The results showed that the cloned goat ST13 gene was 1 380 bp, with CDS of 1 101 bp, encoding 366 amino acids. Protein prediction results showed that ST13 had 26 phosphorylation sites and that some sequences were highly hydrophilic and unstable. Moreover, ST13 was a non-transmembrane and non-secretory protein. Subcellular localization demonstrated that ST13 was mostly distributed in the nucleus (69.6%). Phylogeny analysis suggested that goat ST13 had the highest identity to sheep ST13. Tissue expression pattern showed that ST13 gene expressed in all of the collected 13 tissues of goat, including heart, liver, spleen, lung and kidney, especially in triceps brachii and subcutaneous fat (P < 0.01) and that the expression among heart, liver, spleen, lung, kidney, large intestine, small intestine and pancreas was insignificantly different (P > 0.05). In addition, according to the temporal expression pattern in adipocytes, the expression of ST13 was up-regulated in differentiated adipocytes, and the expression was the highest at the 108th hour of induction, significantly higher than that at other time points (P < 0.01). In conclusion, this gene expresses in various tissues of goat and regulates the differentiation of goat subcutaneous adipocytes.
Adipocytes ; Animals ; Cloning, Molecular ; Goats/genetics* ; Liver ; Phylogeny ; Real-Time Polymerase Chain Reaction ; Sheep