1.An analysis of external quality control results of iodine deficiency disorders network laboratories in Ningxia from 2002 to 2012
Xueqin WANG ; Yajun ZHANG ; Jun ZHAN
Chinese Journal of Endemiology 2014;33(1):101-103
Objective To analyze the examination results of external quality assessment(EQA),at all levels of iodine deficiency disorders(IDD) net work laboratories in Ningxia from 2002 to 2012,and to provide a reliable laboratory quality assurance for surveillance and control of IDD.Methods The data of IDD network laboratories at Ningxia provincial,municipal and county levels from 2002 to 2012 were collected and analyzed.Results Both of the response rate and qualification rate of salt iodine and urinary iodine laboratories at the provincial level were 100% in the past 11 years.The response rate and qualification rate of salt iodine laboratories at municipal level were also 100% ; the response rate of urinary iodine was 100% since 2005,and the qualification rate had been 100% for six years since 2007.The response rate of salt iodine at county level had been 100% since 2004,and the qualification rate had been 100% for four years since 2009.Conclusions IDD network laboratory in Ningxia Province runs good,and the quality control measures are solid and effective.
2.To investigate the relationship of antithrombin-Ⅲ activity and thrombosis risk in liver cirrhosis with child-pugh classification
Bin GUO ; Ning XIE ; Meng YU ; Xiao CHEN ; Xueqin ZHAN ; Zhonghai FEI ; Junan LI
International Journal of Laboratory Medicine 2016;37(18):2581-2582,2586
Objective To investigate the relationship of antithrombin‐Ⅲ activity and thrombosis risk in liver cirrhosis with Child‐Pugh classification .Methods In our hospital from June to December 2014 ,60 liver cirrhosis patients were selected randomly included into this experiment group ,The 60 cases of control group were from medical examination of health in our hospital .The plasma AT‐Ⅲ activity and D‐D concentration in all these cases were detected and analyzed .Results The AT‐Ⅲ in cirrhosis patients were significantly lower than which in healthy persons(P<0 .05) .The lower level of AT‐Ⅲ is in these patients which were in seri‐ous condition(P<0 .05) ,the abnormal rate of D‐D concentration is also higher at the same time(P<0 .05) .Conclusion The detec‐tion of AT‐Ⅲ level in patients with liver cirrhosis is directly related to the severity of clinical and thrombosis risk .The AT‐Ⅲ de‐tection level can be used to judge the patient′s condition and develop appropriate treatment strategies .
3.The influence of comprehensive psychological intervention on the immune function of patients with nasopharyngeal carcinoma
Xiaomei HUANG ; Juan ZHAO ; Lianbin LIU ; Yi LIU ; Shufang ZHU ; Xiaojuan ZHOU ; Bin ZHAN ; Xueqin ZENG
Chinese Journal of Practical Nursing 2017;33(32):2488-2492
Objective To explore the influence of psychological intervention on the immune function of patients with nasopharyngeal carcinoma. Methods Forty nasopharyngeal carcinoma patients with concomitant radiochemotherapy were divided into intervention group and control group by random digits table method with 20 cases each.Among concomitant radiochemotherapy nasopharyngeal carcinoma patients, intervention group were treated with comprehensive psychological behavior, and control group received only concurrent radiotherapy and chemotherapy. Both groups were investigated by Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS).Natural killer cells activity were measured by flow cytometry. Results There were no significantly difference in score of SDS and SAS between two confirmed groups(P>0.05).After treatment,the score of SDS and SAS in intervention group were(45.26± 3.83), (42.57 ± 3.75) points, which were significantly lower than those of control group (52.68 ± 3.66), (51.16 ± 3.62) points, the difference was statistically significant(t =6.264, 7.370, P<0.05). Meanwhile, natural killer cell activity between two groups showed no significantly difference (P>0.05). However, the activity of natural killer cells in intervention group was 26.96±9.01,which was higher than that of control group 22.84 ± 7.19, there were statistically significant difference between two groups (t=2.120, P<0.05).There was a positive correlation between the value difference of SDS scores,SAS scores and natural killer cell activity between two groups (r=0.238, P=0.006; r=0.527, P=0.003). Conclusions Comprehensive psychological intervention can significantly not only improve the depression and anxiety of nasopharyngeal carcinoma patients,but also enhance the activity of natural killer cells,which help maintain the leukocyte level of patients.
4.Mechanism of allergen specific immunotherapy and its influence on lung function in asthma children
Jinling LIU ; Yanfen LIN ; Xueqin ZHAN ; Yingshuo WANG ; Zhimin CHEN
Chinese Journal of Applied Clinical Pediatrics 2020;35(21):1610-1613
Asthma is a common chronic airway inflammatory disease in children.Currently, symptomatic control can be achieved in the majority of patients through a combination of β 2 receptor agonists for rapid relief of symptoms and inhaled corticosteroids for long-term control.As the only causal treatment modality at present, allergen-specific immunotherapy (AIT) may modify the natural course of asthma, and can control the symptoms, reduce airway hyperresponsiveness and improve lung function.In order to provide evidence for improving the effect of AIT on asthma, the mechanism of AIT in asthma and its effect on lung function were discussed in this paper.
5.Survey of prevalence of iron deficiency and iron deficiency anemia in pregnant women in urban areas of China
Guolin HE ; Xin SUN ; Jing TAN ; Jing HE ; Xu CHEN ; Caixia LIU ; Ling FAN ; Li ZOU ; Yinli CAO ; Mei XIAO ; Xueqin ZHANG ; Guohua ZHANG ; Wei ZHOU ; Yan CAI ; Xianlan ZHAO ; Yan GAO ; Hongmei LI ; Xiuli LIU ; Hongping ZHANG ; Yun WANG ; Hui TANG ; Ningxia YUAN ; Guifeng DING ; Fang ZHAN ; Chunxia YIN ; Jiewen ZHANG ; Hongmei YANG ; Yana QI ; Xinghui LIU
Chinese Journal of Obstetrics and Gynecology 2018;53(11):761-767
Objective To investigate the prevalence of iron deficiency(ID)and iron deficiency anemia (IDA) in pregnant women in urban areas of China. Methods The study was a national cross-sectional survey conducted from September 19th, 2016 to November 20th, 2016. According to the classification of the National Bureau of Statistics, all survey sites were set up in 6 regions of the country. Pregnant women were continuously selected using multistage stratified sampling. A total of 12 403 pregnant women were collected and examined for serum ferritin and hemoglobin levels. Results The median serum ferritin level during pregnancy was 20.60 μg/L(11.78-36.98 μg/L), the hemoglobin level was(118±12)g/L. With the progress of pregnancy, the levels of serum ferritin and hemoglobin decreased gradually. The median serum ferritin levels in the first, second trimester and third trimester were 54.30 μg/L(34.48-94.01 μg/L), 28.60 μg/L(16.40-50.52 μg/L), and 16.70 μg/L(10.20-27.00 μg/L)respectively(P<0.01). The mean hemoglobin levels were(127 ± 10)g/L,(119 ± 11)g/L and(117 ± 11)g/L respectively(P<0.01). The prevalence of ID in urban pregnant women was 48.16%(5 973/12 403), and IDA prevalence was 13.87% (1 720/12 403). The prevalence of IDA in the first, second trimester and third trimester were 1.96% (20/1 019), 8.40%(293/3 487)and 17.82%(1 407/7 897), respectively(P<0.01). The prevalence of standardized ID and IDA were significantly different in various regions of China(P<0.01). The standardized prevalence of ID were relatively higher in East China and Northeast China, 57.37% and 53.41% respectively, while it was the lowest in Southwest China, 30.51%. The standardized prevalence of IDA in South Central, Northwest, and East China were relatively high, 21.30%, 16.97% and 17.53% respectively, and the standardized prevalence of IDA in Southwest China was the lowest, 5.44%,the differents in various regions were significant(all P<0.01). Conclusion The current phenomenon of ID and IDA in pregnant women is still very common,and nutrition and health care during pregnancy should be strengthened.