Adolescent ; Arrhythmias, Cardiac ; etiology ; Child ; Child, Preschool ; Echocardiography ; Heart Neoplasms ; diagnosis ; epidemiology ; etiology ; physiopathology ; Humans ; Incidence ; Infant ; Infant, Newborn ; Rhabdomyoma ; diagnosis ; epidemiology ; etiology ; physiopathology ; Risk Factors ; Tuberous Sclerosis ; complications ; diagnosis ; epidemiology

Objective To study the reliability and validity of the Chinese version of AKT(the Apnea Knowledge Test).Methods The AKT was tested in a sample of 91 middle aged and elderly patients with obstructive sleep apnea and hypopnea syndrome and the AKT was retested in 30 of them after 1 month.Results Cronbach's alpha reliability coefficient was 0.76.Retest correlation coefficient was 0.96.There was significant difference between test and retest.Item analysis indicated that there was significant difference in most items between higher scores group and lower one except the fourth item.Conclusions AKT has satisfying reliability and validity which is suitable for evaluation of sleep apnea knowledge.

Objective To explore the cognitive changes of patients with MCI using the Montreal Cognitive Assessment(MOCA) for elderly preliminarily.Methods 85 normal controls (NC),117 subjects with mild cognitive impairment (MCI) and 73 patients with Alzheimer's disease (AD) were assessed with the MOCA.Results There were significant differences among the three groups in all items of MOCA(F=258.66,P＜0.01).Significant differences were observed in almost all the sub-tests between MCI group and NC group or MCI group and AD group(visuopatial F=54.86,P＜0.01;naming F=17.30,P＜0.01;attention F=82.50,P＜0.01;language F=25,88,P＜0.01;abstraction F=15.00 ,P＜0.01;delayed recall F=130.49,P＜0.01;orientation F=176.09,P＜0.01.).The most significant differences were found in delayed recall and orientation among three groups(F=176.09,P＜0.01;F=130.49,P＜0.01.).At 26 cut-point,The results of screening of the MOCA agree with the gold standard of clinical diagnose for the patient with MCI.The agreement rate for observation was 0.93.The agreement rate by chance was 0.61.The Kappa was 0.85.Conclusions The MOCA appropriately define MCI,NC and AD in their cognitive function,it has good discriminant validity.The test of delayed recall and orientation may be more sensitive in the detection of the older people.The MOCA is a useful screening instrument for the patient with MCI.

To improve the vocational nursing students' interest in learning physiology,‘four modernizations' teaching method was preliminarily explored in physiology teaching practice.‘Four modernizations' referred to the teaching by using multimedia.Using this method,we can simplify complex issues,inspire students' curiosity and thirst for knowledge,combine with real life,make abstract problem specific,mobilize students' initiative,contact with clinical practice,visualize theoretical issues,strengthen the importance and understanding and make moderate expansion so that professional skills and practicality of nursing can be emphasized.

Objective To investigate the clinical application of ALT detection based on microtiter plate kinetic method in the au‐tomatic enzyme immunoassay system .Methods By beference to the IFCC recommended kinetic method ,microtiter plate kinetic method was established in the automatic enzyme immunoassay system of ALT detection .The linear ,intro‐batch and inter‐batch du‐plicability of the method were evaluated .ALT test results of 823 samples with microtiter plate kinetic method and automatic bio‐chemistry analyzer method were compared .Results Microtiter plate kinetic method had good linearity where ALT activity <303 U/L ,the intra batch and inter batch variation coefficients < 1/5TEa .The detection results of the clinical samples were correlated with the biochemical analyzer .Conclusion Microtiter plate kinetic method to detection ALT in the automatic enzyme immunoassay system is an ideal method for simultaneous detection of ALT and ELISA in large batch samples ,which is worth popularizing .

Objective To evaluate the impact of family intervention on the quality of life in the patients after total laryngectomy and their family members. Methods Family intervention was implemented for the patients after total laryngectomy and their family members from 2008 to 2009,and only patients received intervention from 2005 to 2007. The patients and their family members were investigated with Quality of Life Instrument for Cancer Patients-Head and Neck Cancer (QLICP-HN) and Quality of Life Scale-Family Version (QOL Scale-FAMILY) respectively when the patients were admitted to hospital and one year after discharged. Results The quality of life in patients after total laryngectomy and their family members was significantly improved after family intervention was implemented (P<0.05). Conclusion Family intervention is practicable and helpful to improve the quality of life in patients after total laryngectomy and their family members.

Objective To evaluate the relationship between cavitas pelvis fluidify and infertility.Methods The clinical data of 129 infertility patients which ultrasound hint cavitas pelvis fluidify but hysterosalpingography hint both fallopian tubes to be unobstructed were analyzed retrospectively. The patients were divided into two groups, after 3 months cure with traditional Chinese medicine, the cavitas pelvis fluidify of 86 cases were obsolescent as group Ⅰ , the cavitas pelvis fluidify of 43 cases were no obsolescent as group Ⅱ. Compared their pregnancy rates. Results The pregnancy rate of group Ⅰ was 30.23%(26/86),group Ⅱ was 6.98%(3/43 ), there was significant deviation between the two groups (P < 0.05 ). Eighty-seven patients who were no pregnant were diagnosed laparoscopy, there were 55 cases with endometriosis (EMS), 25 cases with cavitas pelvis accretion, 1 case with tuberculosis of peritoneum, 6 cases with carmoisine cavitas pelvis fluidify without other abnormal. Thirty-one of these patients were pregnant through in vitro fertilization and embryo transfer. Conclusion Cavitas pelvis fluidify is very important in clinic, search for the cause of a disease and cure actively is needed, so that they can cure utility.

Objective To investigate the incidence of pain for the.elderly with dementia in our country.Methods The Chinese version of Doloplus-2 was used to assess pain in 103 patients with dementia.Results One or more specific diseases may cause pain in 94 patients,degeneration of bone and joint top of the list;69 patients with pain score geater than or equal to 5 points,the incidence of pain as much as 67% .Older persons in different age groups the incidence of pain is different,with the age increased the incidence of pain increased;different older age groups pain scores had no significant difference.Conclusion Pain in patients with dementia should be of great importance to the medical staff and give full play to the nursing staff in pain management.

Objective To explore the application effect of laparoscopic resection of colorectal cancer in elderly patients.Methods 220 patients with colorectal cancer were selected and divided into the study group and the control group,ll0 cases in each group.The patients of the control group were treated with abdominal surgery.The patients of the study group were given laparoscopic surgery.The operative time,blood loss,anal exhaust time,postoperative hospital stay,and postoperative complications,pull tube time of the two groups were compared.Results The operative time of the study group was (245.4 ± 23.2) min,which was significantly longer than (214.8 ± 25.1) min of the control group(t =8.759,P =0.026) ; The blood loss,anal exhaust time,postoperative hospital stay,time to pull the tube of the study group were (175.3 ± 18.4)mL,(2.1 ±0.5)d,(13.2 ±0.1)d and (1.2 ±0.3) d,respectively,which were significantly better than those of the control group(t =9.041,9.757,8.969,8.704,P =0.025,0.023,0.027,0.028) ;The incidence rate of complication of the study group was 14.5％,which was significantly lower than 24.5％ of the control group(x2 =11.704,P =0.019).Conclusion Laparoscopic resection of colorectal cancer had better effect,and it can lower blood loss,shorter hospital stays,and has fewer complications.

Dermatology is closely related to the health of officers and soldiers both in peace time and war time. Under special circumstances, skin diseases have a direct impact on efficiency and combat effectiveness of the military. Research work on fungal infections and psoriasis in the PLA has been playing a leading role domestically, as well as reaching international advanced standards. In the past 20 years, PLA dermatologists had been granted 32 second awards of Army Science and Technology Advancement Prize. Among them, the results of a series of research on fungal infections accomplished by the Second Military University was granted a second award of the State Science and Technology Advancement Prize. In the past 5 years, the team of dermatology profession has been growing rapidly in the PLA. Up to now, there are 6 departments with 11 tutors who are entitled to train postgraduate students seeking doctorate degree, and about 100 of them have succeeded in thesis defense and conferred the doctoral degree. However, at present, there are still many problems unsolved and further research is necessary. The most important task is, under the guide of bio-physic-social medical modality, various sophisticated technologies should be applied in basic research, prevention, diagnosis, treatment etc. in the field of dermatology, in order to assure the physical and psychological health of the servicemen.