Objective To explore the application value of evidence-based nursing in prevention of lower limb deep vein thrombosis after hip arthroplasty. Methods 41 cases of patients undergoing hip arthroplasty were selected in our hospital from January 2008 to June 2011.28 cases of patients who took evidence-based nursing were set as the observation group,and the 13 cases of remainders who received routine nursing were named as the control group.The treatment results were compared between the two groups. Results The incidence of deep venous thrombosis was 23.1％ in the control group,significantly higher than the observation group.In the observation group,FIB value,D-D values,CD62p value,DQ values,ZQ value and GQ value were lower,and the PC value was higher than the control group. Conclusions Application of evidence-based nursing in hip arthreplasty can significantly reduce the incidence of lower limb deep vein thrombosis,which is worthy of clinical application.