目的探讨健身秧歌舞对女性更年期综合征的缓解作用。方法对60名有更年期综合征症状的女性实施12周健身秧歌舞练习,分析受试者练习前后血清雌性激素水平及更年期综合征症状的变化。结果受试者血清雌二醇、孕酮含量提高(P<0.05),睾酮含量明显降低(P<0.01),更年期症状阳性率降低(P<0.05)。结论健身秧歌舞能有效缓解女性更年期综合征症状。

Objective: To explore the characteristics of control response and sustained attention in children with chronic tic disorders (CTD). Methods: 38 children fulfilled DSM-Ⅳ diagnosis of CTD and 38 normal children are involved in the study. All participants were assessed with the integrated visual and auditory continuous performance test (IVA-CPT). The differences of sustained attention and control response were compared. Results: Most of the values of IVA-CPT were lower in children with CTD compared with normal children. There was no significant difference between the visual and auditory sustained attention and control response in children with CTD. Conclusion: The present study suggests that control response and sustained attention are both impaired in children with CTD.

Objective To evaluate the clinical efficacy of cefotaxime combined with gamma globulin on neonatal septicemia. Methods The subjects of this study were selected from 88 cases of neonatal septicemia admitted in Jiangyou No.903 hospital from April 2014 to April 2017. They were randomly divided into two groups, each with 44 cases. The control group was given symptomatic treatment and cefotaxime, while the observation group symptomatic treatment, cefotaxime and gamma globulin as well. After 7days of treatment, the overall effective rates, case fatality rates, clinical symptoms (body temperature, resistance to milk, neurological symptoms), time for improvement and hospital stay were compared between the two groups. Results The overall effective rate of the observation group was 95.45％, much higher than 72.73％ of the control group (P<0.01). The observation group had much lower case fatality rate than the control group did (2.27％ vs 18.19％) (P<0.05). The time the observation group took for improvement in the condition of body temperature, resistance to milk, neurological symptoms, and hospital stay was (3.25±1.07) days, (4.93±1.96) days, (5.92±1.58) days, and (6.80±1.94) days respectively, all significantly shorter than the time the control group took (P<0.01). Conclusion The combination of cefotaxime and gamma globulin is effective in the treatment of neonatal septicemia. It can significantly reduce case fatality rate and shorten the time for clinical symptoms and hospital stay.

Objective To study characteristics of clinical manifestations of patients with neuropsythiatric systemic lupus erythematosus(NPSEL). Methods From Jan.2000 to Oct.2004,the symptoms、signs and results of assistant check of 36 patients with NPSEL were analysed and summarized. Results 9 kinds of symptoms are complained,in which headache、weakness and disorder of consciousness were most frequent;13 kinds of signs were found,in which pathologic reflex、disorder of consciousness and limb paralysis were most frequent. Conclusion (1)NPSEL is a kind of manifestation of active SEL.(2)No matter how long disease course of SEL may be,the patients can be involved by NPSEL.(3)Manifestations of NPSEL is complicated.

Five compounds, huyouyisu (1), vomifoliol (2), isoferulic acid (3), 1,2,3-trihydroxy-phenol (4) and p-hydroxy-phenol (5), were isolated from the peels of Citrus changshan-huyou Y.B.Chang for the first time by utilizing repeated column chromatography on silica gel. Among them, huyouyisu (1) is a new compound. The structure was elucidated by using 1D and 2D spectra.

The purpose of this study was to observe whether HBV can infect HSC in vitro. LX-2 cells, the human activated HSC cell line, were incubated with human serum containing HBVDNA at final concen-trations from 0.01 to 10 copies/cell and harvested after 24,48 and 72 hours. Hepatitis B surface antigen (HBsAg) and hepatitis B core antigen(HBcAg) were detected by lmmunohistochemistry dyed by DAB. By Immunohistochemistry, no positive particles in LX-2 cells, a few of dark brown particles (HBsAg and HB-cAg) were found in cytoplasm and nucleoli of HepG2.2. 15 cells,a lot of clark brown particles were found in liver biopsies of patients with chronic hepatitis B. In vitro, there was no evidence that HBV can infect and express antigens in LX-2 cells.

Objective: To analyse the behavioral problems of children with attention deficit hyperactivity disorder.Methods: 70 boys fulfilled ADHD criteria of DSM-IV were further divided into 3 subtypes: predominantly inattentive(PI,44 cases),predominantly hyperactive-impulsive(HI,6 cases) and combined type(CT,20 cases).Compare the behavioral problems of subtypes of ADHD and 63 normal children.Results: The incidence of behavioral problems in boys with ADHD(48.57%) was significantly higher than that in control group(12.70%),and significant differences in incidence of behavioral problems were found among the three subtypes of ADHD.ADHD CT subtype had the highest rate of behavioral problems.PI subtype had more fissility than HI;CT and HI subtypes had more aggressive behaviors,and HI had more delinquence than PI and CT.Conclusion: Boys with ADHD had more behavioral problems than normal ones.CT subtype had the highest rate.The characteristics of behaviors were different among three subtypes.

Objective To evaluate the neonatal outcomes and the prevalence of congenital malformations in children born after in-vitro fertilization(IVF). Methods IVF children (211 cases) born of 156 mothers from July 1994 to October 2003 and 218 controls were studied. Those controls were randomly chosen from the same hospital matched for the time and season of birth and maternal age. Results The incidence of multi-gestation (37.2% vs 2.3%, OR =24.62, 95% CI : 9.1~72), preterm birth (37.2% vs 8.5%, OR =6.41, 95% CI : 3.5~12.0), cesarean section (97.0% vs 71.8%, OR =14.9,95% CI :5.0~49.5), pregnancy-induced hypetension (22.4% vs 10.8%, OR = 2.39, 95% CI :1.3~4.9), threatened abortion (4.5% vs 0%, OR =3.11,95% CI :2.0~4.8) were significantly higher in the IVF group, but the prevalcnce of fetal distress (14.6% vs 4.5%) was lower comparing with control group( P

Objective To further study on the chemical constituents in the peels of Citrus changshan-huyou.Methods The chemical constituents were separated by repeated silica gel column chromatography,the structures were determined by spectral analyses.Results Ten compounds were obtained and identified as huyoujiasu(2'-hydroxy-malonyl-3,4-dihydroxybenzoic acid,Ⅰ),3'-hydroxy-4',5,6,7,8-pentamethoxyflavone(Ⅱ),eriodictyol(Ⅲ),tetracosanoic acid(Ⅳ),glyceryl dodecanoate(Ⅴ),neoeriocitrin(Ⅵ),naringin(Ⅶ),neohesperidin(Ⅷ),4-methoxy-3-hydroxybenzoic acid(Ⅸ),and 3,4-dihydroxybenzoic acid(Ⅹ).Conclusion 2'-hydroxy-malonyl-3,4-dihydroxybenzoic acid is a new compound and the above ten compounds are obtained from this plant for the first time.

Objective: To investigate the action and mechanism of Bupleurum chinense SD and Schisandra chinensis Turcz extract on liver fibrosis in rat.Methods: The model was prepared by injection of 40% CCl 4 plant oil solution, then the enzyme active AST、AST、MAO、ALP、r-GT、TG in serum and MAO、ALP、GSH、TG in hemogeneous were measured by enzyme method, the level of Pc-Ⅰand PcⅢ were measured by radio-immunity. Results: Bupleurum chinense and Schisandia chinensis extract can reduce significantly enzyme active of ALT、AST、TG、MAO in serum of fibrosis rat, the GSH was elevated and the r-GT was not effect in serum, but it could reduce the level of MAO、ALP、Pc-Ⅰ、Pc-Ⅲ in the homogeneous, sometime the TG was increased and the GSH was not effect in homogeneous. The histopathology showed that Bupleurum chinense and Schisandia chineusis extract could get damaged liver cell back and reinforce the regeneration of hepatic cell. Conclusion:Bupleurum chinense and Schisandid chinensis extract the action of protective and restoration on injured liver cell, and its could eliminate the bile accumulation, to retard the fatty degeneration in fibrotie rat.