1.Quality Control of Shentekang Capsules
Xuelai HU ; Guangxi LIU ; Xiaoju PENG ; Hongling ZHOU
China Pharmacy 1991;0(03):-
OBJECTIVE:To establish a method for quality control of Shentekang capsules.METHODS:The Radix astragali,Radix ginseng,fermental cordyceps powder in this medicine were identified by TLC.The contents of berberine hydrochloride in this medicine were measured by HPLC.RESULTS:The spots in TLC were clear and well distinguished.The method was linear within a range of0.0351~0.263?g for berberine hydrochloride(r=0.9999),the average recovery was98.88%,and RSD=1.07%(n=5).CONCLUSIONS:The method is simple,sensitive and accurate,which can be used to control the quality of Shentekang capsules.
2.Effects of enhanced recovery nursing based on traditional Chinese medicine nursing operation technology in perioperative period of elderly patients with total hip arthroplasty
Yeyan LIN ; Jing ZHU ; Cunxian LYU ; Shaoxi XIANG ; Xuelai ZHOU ; Haijing CHEN
Chinese Journal of Modern Nursing 2022;28(33):4700-4704
Objective:To explore the effect of enhanced recovery nursing based on traditional Chinese medicine nursing operation technology in the perioperative period of elderly patients with total hip arthroplasty.Methods:From January 2020 to December 2021, 90 patients with unilateral total hip arthroplasty in Wenzhou Traditional Chinese Medicine Hospital were selected by convenience sampling as research objects. The patients from January to December 2020 were taken as the control group ( n=43) , and the patients from January to December 2021 were taken as the observation group ( n=47) . The patients in the control group adopted the traditional orthopedic perioperative nursing, while the patients in the observation group received the enhanced recovery perioperative nursing based on traditional Chinese medicine nursing operation technology on the basis of the control group. The pain, postoperative recovery and complications were compared between the two groups. Results:The time of first exhaust, eating, getting out of bed and hospital stay after operation in the observation group were shorter than those in the control group, the Visual Analogue Scale (VAS) score at discharge was lower than that in the control group, and the incidence of postoperative gastrointestinal reactions and postoperative urinary retention were lower than those in the control group, with statistically significant differences ( P<0.01) . Conclusions:The enhanced recovery nursing based on traditional Chinese medicine nursing operation technology applied to elderly patients with unilateral total hip arthroplasty during perioperative period can reduce postoperative complications, pain and hospital stay, which is worthy of clinical promotion.
3.Effects of Baihe Gujin Decoction Combined with Shenmai Injection on Therapeutic Efficacy and Related Indexes in Elderly Patients with Ventilator-associated Pneumonia
Xuelai ZHOU ; Yuan YANG ; Wei DAI ; Zhihong XUAN ; Yifei WANG
China Pharmacy 2020;31(21):2645-2650
OBJECTIVE:To investigate t he effects of Baihe gujin decoction combined with Shenmai injection on therapeutic efficacy and related indexes in elderly patients with ventilator-associated pneumonia. METHODS :A total of 75 elderly patients with ventilator-associated pneumonia who were admitted to the Intensive Care Unit (ICU)of Zhuji Hospital of TCM from Apr. 2018 to Oct. 2019 were included. They were randomly divided into control group ,Shenmai group ,Baihe gujin decoction+Shenmai group , with 25 cases in each group. Control group was given conventional treatments as Piperacillin sodium tazobactam sodium injection 4.5 g,ivgtt,q8 h for anti-infective treatment+ Ambroxol hydrochloride injection 4 mL,iv,bid for expectorant+ Doxofylline injection 20 mL,qd for relieving spasm and asthma+maintaining water ,electrolyte and acid-base balance. Shenmai group was given Shenmai injection 100 mL,ivgtt,qd,on the basis of control group. Baihe gujin decoction+Shenmai group was given Baihe A101) gujin decoction 200 mL nasally , morning and evening ,on m the basis of Shenmai group. Each group took 7 days as a course of treatment ,and the treatment was continued for 2 courses. Acute physiology and chronic health status (APACHE)Ⅱ score,C-reactive protein (CRP)in peripheral blood ,procalcitonin(PCT),bronchial CD 68 count were observed in 3 groups before and after treatment while the mechanical ventilation time ,hospitalization time in the ICU and ADR recorded. RESULTS:Before treatment ,there was no statistically significant difference in APACHE Ⅱ score,the levels of CRP and PCT , bronchial CD 68 count among 3 groups(P>0.05). After 14 days of treatment ,APACHE Ⅱ score,CRP and PCT levels of all 3 groups were significantly lower than before treatment ;bronchial CD 68 count was significantly higher before treatment ,the order of bronchial CD 68 cell count was Baihe gujin decoction+Shenmai group >Shenmai group >control group (P<0.05 or P<0.01);after 7 days of treatment ,the order of CRP and PCT levels was Baihe gujin decoction+Shenmai group <Shenmai group <control group (P<0.05);after 14 days of treatment ,there was no staistically significant difference in APACHE Ⅱ score,CRP and PCT levels among 3 groups(P>0.05). After treatment ,the order of mechanical ventilation time and ICU hospitalization time was Baihe gujin decoction + Shenmai group <Shenmai group <control group (P<0.05 or P<0.01). There was no significant difference in the incidence of ADR among 3 groups(P>0.05). CONCLUSIONS :Based on routine treatment ,Baihe gujin decoction combined with Shenmai injection can improve the immune function of lung macrophages in the elderly patients with ventilator-associated pneumonia,inhibite pulmonary inflammation progress ,reduce mechanical ventilation time ,shorten the length of hospital stay with good safety.