1.The relation between the morphological change of supratubal recess and otitis media
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2010;(1):21-24
Objective:To observe the anatomic characteristics of supratubal recess and the morphological change of it in the sick ear. To investigate the relation between the morphological changes of supratubal recess and otitis media.Method:Using high resolution CT to observe and measure the supratubal recess of the normal ears and the ailing ones.Result:For the normal adults, the anteroposterior diameter of the supratubal recess is(3.83±1.28)mm,the vertical diameter(3.67±1.14)mm,the height(3.76±0.36)mm;and the length of the cog is(2.84±0.38)mm.The size of the supratubal recess showed no significant difference between left and right(P>0.05).There was no relationship between the size of the supratubal recess and pneumatization of mastoid cells (P>0.05).There was significant differences in size of the supratubal recess between normal ears and the ears with cholesteatoma(P<0.05),but there was no relationship between the size of the supratubal recess and pneumatization of mastoid cells(P>0.05)in the ears with cholesteatoma.There was no significant differences in size of the supratubal recess between normal ears and the ears with chronic otitis media(P>0.05).In the ears with cholesteatoma,40% had osseous destruction in supratubal recess.Conclusion:For the normal adults, the size of the supratubal recess showed no significant difference between left and right, and there was no relationship between the size of the supratubal recess and pneumatization of mastoid cells. Anterior tympanic isthmus , posterior tympanic isthmus and supratubal recess which is the supplement of the formers constitute the air way between attic and mesotympanum. The supratubal recess of the cholesteatoma is smaller than the normal, when the eustachian tube dysfunction occurs, the air way in the middle ear would herein be affected, and cholesteatoma forms eventually. There was no significant differences in size of the supratubal recess between normal ears and ears with chronic oti-tis media, as in the clinic.The effect of the supratubal recess should be taken into account when we consider the pathogeny and treatment of the middle ear cholesteatoma.
3.Experimental Research of Acupuncture at Zusanli(ST 36)for Anti-aging
Yicong XIE ; Fang TANG ; Xuejun CUI
Journal of Acupuncture and Tuina Science 2008;6(6):334-336
Objective: To explore the mechanism of anti-aging effect of acupuncture at Zusanli (ST 36). Methods: Thirty mice of 28 weeks old were randomly divided into 3 groups: control group, model group and acupuncture group. Sub-acute aging model was established by subcutaneous injection of D-galactose. The activity of Superoxide Dismutase(SOD) and content of serum Malondialdehyde(MDA) were measured. Morphological changes of jejunal mucosa were observed with light microscope. Result: SOD activity in the acupuncture group was highest among the three groups, whereas, MDA content was the lowest. In the model group, the ratio of normal intestinal villus was decreased, the intestinal villus was shrunk, and there were more epithelial cells desquamated. In acupuncture group, there were less abnormal intestinal villus and epithelial cell. Conclusion: Acupuncture at Zusanli (ST 36) has an effect in resisting aging by increasing the activity of serum SOD, decreasing the MDA contents, and improving the intestinal villus.
4.Acoustic densitometric analysis of phases in normal rabbit liver contrast enhancement using intravenous second harmonic imaging
Fenglin WU ; Xuejun FANG ; Jia LIU
Chinese Journal of Ultrasonography 2003;0(12):-
Objective To investigate phases in normal rabbit liver contrast enhancement with the acoustic densitometry(AD).Methods Ten cases of normal rabbit were examined with second harmonic imaging(SHI).The AD curves and data of parenchyma were compared before and after the portal blood flow was blocked,when the contrast agents were administrated through ear veins.The AD curves and data of parenchyma were also investigated when the contrast agents were injected via ear veins and mesenteric veins.Results The curves of normal rabbit liver parenchyma were single-peak-shaped,looking like "a verticle triangle",when the contrast agent was administrated through ear veins.The curve was divided into 3 sections: ascending,summit,descending,with the value of peak intensity ( 18.4 ? 1.7 )dB.Ascending section indicated the arterial phase,and summit and descending sections the portal phase.The AD curves were quite similar before and after the portal blood flow was blocked,only with the peak value slightly decreased,and the values of peak intensity decreasing by 2 dB.Two peaks were seen in the "Hump-like" AD curves in the parenchyma,with the second peak higher than the first,as the contrast agents were administrated through mesenteric veins again 10-15 seconds after administration via ear veins.Conclusions The arterial phase is short and portal phase is long in normal rabbit liver contrast sonography.The enhancement of parenchyma is caused mostly by contrast from hepatic artery,and the contrast from portal veins only plays a minor role.
5.Change of calcimn metabolism in liver mitochondria and its effect on mitochondrial respiratory function fol- lowing biliary obstruction
Jing LI ; Yanbang CHI ; Xuejun FANG
Chinese Journal of Hepatobiliary Surgery 1998;0(06):-
Objective To explore the change of liver mitochondrial calcium metabolism and its effect on mitochondrial respiratory function.Methods The model of dog biliary obstruction was made by bile duct ligation. Mitochondria were obtained by differential centfifugation.Mitochondrial calcium content,calcium uptake rate and respiratory function were observed and compared.Results Liver mitochondrial calcium content was increased sig- nificantly,calcium uptake rate and respiratory function were obviously reduced after biliary obstruction.Mitochon- drial calcium content was highly negatively correlated with mitochondrial respiratory function (P
6.Laparoscopic hepatic left lateral lobectomy: report of 11 cases
Chaolong LI ; Jianhua LIN ; Xuejun FANG
Chinese Journal of General Surgery 1993;0(02):-
Objective To investigate the safety and feasibility of laparoscopic hepatic left lateral lobectomy. Methods Five cases of liver cancer, 4 cases of hepatic hemangioma, and 2 cases with suspected liver tumors were included in this series. Tumors were all located at left lateral lobe, with a diameter less than 10?cm. Tumors were resected by laparoscopy under a combination of pneumoperitoneum and non-pneumoperitoneum, with hand assistance through a mini-incision. Several manoeures were used for the dissection of liver tissue, including microwave coagulation, ultrasonic dissection, tainium clips clamping, rotating suction, endogia ligation. ResultThe procedure was successful in all cases with the operation time ranging from 1.5?h to 6?h, and bleeding was 50?ml to 500?ml. The hospitalization time were from 5?d to 15?d. ConclusionLaparoscopic liver resection is safe and feasible for the left liver lateral lobe tumor when the diameter is less than 10?cm, and not involving surrounding organs.
7.Correlative study on changes of liver mitochondria calcium content and respiratory function in obstructive jaundice and biliary drainage
Xuejun FANG ; Yanbang CHI ; Jing LI
Chinese Journal of Hepatobiliary Surgery 1998;0(06):-
Objective To elucidate the relationship between liver mitochondria calcium content and respi- ratory function in obstructive jaundice and biliary drainage.Methods The model of obstructive jaundice and bil- iary drainage was produced in dogs by common bile duct ligation and choledochoduodenostomy.The liver mitochon- dria were isolated and the calcium content and respiratory control rate were monitored.Results Mitochondria res- piratory control rate and calcium content significantly decreased and elevated respectively after bile duct ligation and there were varying degrees of recovery after biliary drainage,and the degree of recovery was evidently correlated with the duration of obstruction before drainage and the time after drainage.There was a strong negative correlation between the mitochondria calcium content and change of respiratory function.Conclusion The mitochondria cal- cium overload may be one of important factors for suppressed mitochondrial respiration in obstructive jaundice and early relief of the obstruction could favour the recovery of damaged liver mitochondria.
8.Research on continuous measurement of blood pressure via characteristic parameters of pulse wave.
Journal of Biomedical Engineering 2002;19(2):217-220
A new method for continuous measurement of blood pressure (BP) via selecting characteristic parameters of pulse wave pertinent to BP is presented in this paper. In order to validate the precision of the measurement, we have developed a Tonometer. The results of the instrument based on this method are precise if the subjects are at rest. This instrument could be used for BP monitoring of critically ill patients and in common medical researches; it might be applied to BP monitoring during spaceflight and in daily life after movement artifact being restrained.
Blood Pressure
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Blood Pressure Monitoring, Ambulatory
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instrumentation
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Humans
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Manometry
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Pulse
9.The clinical value of postoperative aerobic exercise and psychological intervention on postoperative rehabilitation in patients with breast cancer
Jingtao SHAO ; Rengui FANG ; Xuejun WANG ; Miaoman YE
Chinese Journal of Primary Medicine and Pharmacy 2017;24(5):771-774
Objective To investigate the clinical values of postoperative aerobic exercise and psychological intervention in patients with breast cancer after operation.Methods One hundred patients with breast cancer admitted to our hospital were prospectively studied.All patients underwent modified radical mastectomy and were randomly assigned into observation group (50 cases)and control group (50 cases).The patients in the observation group were treated with aerobic exercise and psychological intervention,and the health education was given in the control group. The 3 -month postoperative self -rating anxiety scale score,self -rating depression scale score,shoulder mobility, degree of limb edema and 6 -month postoperative health related quality of life (SF -36)of the two groups were observed.Results There were no significant differences between the two groups in preoperative self -rating anxiety scale score,self -rating depression scale score,degree of limb edema and health related quality of life (all P >0.05).However,the self -rating anxiety scale score of the observation group three months after operation significantly decreased compared with the control group[(40.94 ±9.20)points vs.(45.84 ±8.79)points,t =2.722,P =0.008];self -rating anxiety scale score significantly decreased[(40.18 ±9.96)points vs.(45.28 ±8.67)points,t =2.730, P =0.008];the degree of limb edema was significantly reduced[(10.00 ±6.27)mL vs.(18.52 ±7.20)mL,t =6.313,P =0.000].The health related quality of life 6 months after operation was significantly improved[(78.70 ± 8.85)points vs.(72.02 ±9.76)points,t =3.584,P =0.001 ].Compared with the control group,the shoulder flexion,extension,abduction,external rotation and internal rotation of the observational group were significantly increased at 3 months after operation (all P <0.05 ).Conclusion Postoperative rehabilitation and psychological intervention contribute to the rapid recovery in patients with breast cancer after operation.
10.Discussion on differences of Chinese medicine syndromes evolution regularity between acute stroke patients with and without hypertension
Shan REN ; Zhigang CHEN ; Fang GAO ; Xuejun LI
International Journal of Traditional Chinese Medicine 2013;(1):8-10
Objective To discuss evolution regularity of Chinese Medicine Syndromes and neurological impairment of acute stroke patients with and without hypertension,and to contrast differences between the two groups.Methods Case observation table of "Clinical diagnosis and treatment of stroke patients dialectical law mining and verification of the program of treatment was adopted to record clinical diagnostic messages of 63 cases of non-hypertension and hypertension acute stroke patients.Results ①Contrasting syndrome dements between the two groups it showed that on the tenth day,scores of yin deficiencyin non-hypertension group score (12.83 ±9.97) increased significantly than hypertension group score (8.64±5.90) with statistical significance (P<0.05) ; on the fourteenth day,scores ofblood deficiency in hypertension group score (12.21±7.71)increased significantly than non-hypertension group score (8.07±8.61),with statistical significance (P<0.05).② In hypertension group,from the first day to the fourteenth day of admission,scores of wind,hot and phlegm gradually reduced,but scores of blood deficiency gradually score (9.85 ±7.23) increased,with statistical significance.In non-hypertension group,from the first day to the fourteenth day of admission,scores of wind,hot and phlegm gradually reduced,but scores of yin deficiency gradually score (12.21±7.71)increased,with statistical significance (P<0.05).Conclusion Hypertension turns blood defiency more prominent in evolution of Chinese medicine syndromes of stroke.