Objective To investigate the prevalence of gout and its associated factors in populations in Beijing. Methods A cross-sectional study of gout was carried out in state-employees who had yearly health examination at Peking Union Medical College Hospital in Beijing,China from September to December 2005. The prevalence of gout was calculated in the population. Data were further analyzed by multivariate logistic regression models to find associated factors of gout. Results The prevalence of gout in the population was 1.0%,and were 1.5% and 0.3% for men and women respectively. Bivariate and multivariate logistic regression analysis found that male gender (OR 15.07,95%CI 1.79～127.19),hard liquor (OR 4.93,95%CI 1.41～17.31 for ≥7 beverages per week),diuretics (OR 6.72,95%CI 2.34～19.34),waist obesity (OR 4.38,95%CI 1.33～14.43),and hypercholesterolemia (OR 3.63,95%CI 1.23～10.67 for serum cholesterol 5.17～6.21mmol/L) were associated with increased prevalence of gout,whereas products of bean curd (OR 0.21,95%CI 0.07～0.59) were associated with reduced prevalence of gout. Conclusion Male gender,hard liquor,diuretics,waist obesity and hyperchol-esterolemia may be associated with the increased risk of gout,whereas products of bean curd may be associated with the reduced risk of gout.

Objective To study the relationship between serum uric acid and left atrial size in male patients with essential hypertension.Methods From June 2015 to December 2016,298 males with essential hypertension in the People's Hospital of Guangdong Province were selected.They were divided into normal left atrial group and enlarged left atrial group based on the size of left atrial diameter.The fasting blood glucose,serum lipid,serum uric acid,hepatic and renal function and blood pressure were measured by routine methods,and multivariate logistic regres-sion was used to analyze.Results The average age and serum uric acid level of 298 males with essential hypertension were (55.29 ±8.48)years old and (488.93 ±112.46)μmol/L.There were 47 cases with enlarged left atrial.The serum uric acid level in the enlarged left atrial group was significant higher than that in the normal left atrial group [(512.21±90.82 )μmol/L vs.(474.38 ±94.26 )μmol/L,t ＝9.34,P＜0.001].Pearson correlation analysis showed that serum uric acid level was positively associated with left atrial diameter(r＝0.589,P＜0.001).Multiple logistic regression analysis showed that the serum uric acid level was a risk factor for enlarged left atrial(OR＝1.894, 95%CI:1.13,2.69;P＜0.001).Conclusion Serum uric acid level is positively correlated with left atrial size in male patients with essential hypertension,and is a risk factor for enlarged left atrial.