1.The mechanism of severe acute pancreatitis-associated ascetic fluid production and its influence on body
Xuejin LI ; Xinyuan LU ; Yongyu LI
International Journal of Surgery 2008;35(3):174-177
Acute pancreatitis is one of the common clinical diseases in emergency.The severe acute pancreatitis-associated ascetic fluid is always found in clinic.Its roles related multiple organ dysfunction(MOD)in acute pancreatitis is being understood.In this article,the possible compositions of the ascites,the mechanism of its formation,and its effect on body are recited,in order to better understand the mechanism,the prevention and the treatment of the acute pancreatitis and its compications related MOD.
2.Estimation of the height by measurement results of the body parts
Xiaoming LI ; Chunjie LIU ; Xuejin/ LI
Chinese Journal of Forensic Medicine 1988;0(04):-
In order to study the relationship between the height and the measured results of body parts,the length of the foot,the width of the foot palm,the whole length of the hand,and the length of the forfinger,middle finger,little finger as well as the height of 489 young people were measured.The data was then analyzed by the digital computer.The results showed that the linear relationship existed between the height and the measurement results of six body parts mentioned above in males.The linear regression equations were as follows:(1)y=93 55x+3 26x(by the length of the foot);(2)y=130 79+4 18x(by the width of the foot palm);(3)y=76 15+5 33x(by the whole length of the hand);(4)y=108 61+8 76x(by the length of the forefinger);(5)y=94 85+9 47x(by the length of middle finger);(6)y=120 79+8 68x(by the length of the little finger).Also,the linear relationship existed between the height and the whole length of the hand and the length of the middle finger,The regression equations were as follows:(1)y=119 86+2 44x(by the whole length of the hand);(2)y=129 89+4 08x(by the length of the middle finger).There is not any linear relationship existed between the height and the measurement results of these rwo body parts as mentioned above.
3.A prospective survey of a quadruple-strand semitendinosus tendon versus patellar tendon for anterior cruci-ate ligament reconstruction by arthroscopy
Xuejin LI ; Lide WANG ; Zhiming QI
Chinese Journal of Orthopaedics 1999;0(07):-
Objective The attempts was made to compare the results of a quadruple-strand semi-tendinosus tendon versus patellar tendon reconstruction for anterior cruciate ligament by arthroscopy in chronic complete anterior cruciate ligament injury.Methods60patients were enrolled in a prospective,ran-domized,controlled study.30patients underwent reconstruction with a quadruple-strand semitendinosus tendon autograft,30patients were treated with a bone-patellar tendon-bone autograft.The surgery was car-ried out in an alternating sequence with two autograft constructed materials.At the time of arthoscopy,the knee was examined totally,associated joint pathology was documented,and irreparably torn meniscal frag-ments were removed.60patients were followed up14to30months after operation,and evaluated in terms of the clinical test findings,the activity level,the functional status in daily activities,the range of motion,the stability of the knee,the level of return to sports and the patellofemoral crepitus at final follow-up.Results The objective outcome of replacement with a bone-patellar tendon-bone graft was identical to that obtained with a quadruple-strand semitendinosus tendon graft.The stability of the knee in the quadrupled-strand semitendinosus reconstruction was equal with that in the bone-patellar tendon-bone autograft.The return to sport was more frequent in the quadrupled-strand semitendinosus group comparing with in the bone-patellar tendon-bone group,there was80%and73%in each group respectively with no significant difference.A mild loss(≤3?)of knee extension was more frequent in the patellar tendon group than that in the quadru-pled-strand semitendinosus group,there was40%and6%in each group respectively,the difference was sig-nificant statistically.KT-2000arthrometer side-to-side difference of anterior displancement was13%versus20%in the quadrupled-strand semitendinosus group and patellar tendon group at133.4N.Patellofemoral crepitus was6%and17%in the quadrupled-stranded semitendinosus group and patellar tendon group re-spectively.Conclusion In a chronic complete injury of anterior cruciate ligament,the clinical results of re-construction with a quadrupled-strand semitendinosus tendon or patellar tendon by arthroscopy were satis-factory without significant differences between the two operative procedures.
4.Long-term effects of meniscal allograft transplantation to repair rabbit knee cartilage by different methods
Xuejin LI ; Qun LI ; Zhibo ZHANG ; Hongjian YAN
Chinese Journal of Tissue Engineering Research 2010;14(7):1170-1173
BACKGROUND: There are no ideal substitutes for meniscus. Meniscel allograft transplantation has become a feasible method to retain maniscal function following injury. Currently, the meniscus conservancy methods include fresh meniscus, low temperature preserved meniscus; freeze-dried meniscus.OBJECTIVE: To observe the long-term effects of meniscus allograft transplantation by different methods.METHODS: A total of 70 adult New Zealand rabbits were used, and 30 were selected as meniscus donors. The remaining 40 rabbits were divided into 4 groups (n=10): after meniscectomy, control group was not treated; fresh group underwent fresh meniscus allograft transplantation; low temperature group underwent low temperature preserved meniscus allograft transplantation; freeze-dried group underwent freeze-dried meniscus allograft transplantation. Of 30 donors, 10 received fresh meniscus transplantation, and the other received temperature preserved meniscus and freeze-dried meniscus transplantation 1 week after low temperature and freeze dried preservation. The rabbits were sacrificed 12 months after surgery for gross and histological observation.RESULTS AND CONCLUSION: The meniscus allografts of rabbits healed well, and no rabbits died. Gross observation showed that the appearance and elasticity of fresh meniscus group was similar to normal meniscus; tibial plateau was covered well, with no additional wearing in the cartilage of tibial plateau or condyles of femur. In low temperature and freeze-dried preservation groups,the meniscus grafts healed well, but their volume was small and the elasticity was poor; tibial plateau was only partially covered.Pathological observation suggested that fresh meniscus group had orderly arranged collage fiber and similar chondrocyte appearance, number and distribution to normal meniscus, while sparse collagen fiber end small number of meniscus grafts were observed in the other groups. Results show that meniscal allogrefting can survive, retain certain function and structure and prevent the degenerative changes of the knee joint. Moreover, fresh meniscal grafts exhibit best effects, as the grafts following low temperature or freeze-dried preservation degenerate and their volume diminish 1 year following meniscectomy.
5.Observation on efficacy of endoscopic submucosal dissection and endoscopic mucosal resection in the therapy of esophageal mucosal disease
Hongjian JIANG ; Huanqing WU ; Xuejin LI ; Wenliang HAN ; Chunling ZHAO
Chinese Journal of Postgraduates of Medicine 2014;37(7):54-56
Objective To evaluate the outcome and safety of endoscopic submucosal dissection (ESD) versus endoscopic mucosal resection (EMR) in the management of esophageal mucosal lesion.Methods The clinical data of 70 patients with esophageal mucosal lesion were analyzed.Twenty-five patients were treated by ESD (ESD group) and 45 patients were treated by EMR (EMR group).The enbloc resection rate,tissue healing resection rate,operation time,complication and recurrence rate were compared between two groups.Results The enbloc resection rate,tissue healing resection rate in ESD group were significantly higher than those in EMR group [60.0%(15/25) vs.48.9%(22/45),48.0%(12/25) vs.40.0% (18/45)] (P <0.05).The local recurrence rate in ESD group was lower than that in EMR group [4.0% (1/25) vs.20.0% (9/45)] (P < 0.05).The severe complication such as delayed hemorrhage,perforation,stenosis between two groups had no significant difference (P > 0.05).The operation time in ESD group was (64.3 ±27.1) min,and significantly longer than that in EMR group [(27.6 ± 14.1) min] (P <0.05).Conclusions Compare with EMR,ESD has better enbloc resection rate,tissue healing resection rate,and lower recurrence rate.It is more safe and effective in the therapy of esophageal mucosal disease.
6.The inhibition effects of Zyflamend on DMBA-induced oral carcinogenesis
Fang LI ; Zheng SUN ; Xuejin WANG ; Xiaolin SUN
Journal of Practical Stomatology 2014;(2):188-192
Objective:To study the effects of an unique anti-inflammatory herbal preparation Zyflamend(ZF)on 7,12-dimethyl-benz anthracene (DMBA)-induced oral carcinogenesis in golden Syrian hamsters.Methods:10 hamsters were used as the blank controls.106 hamsters were treated topically on the left cheek pouch with 0.5% DMBA solution,3 times per week for 6 weeks. Then the hamsters in positive control group(n =40)were not treated afterwards,in the other 2 groups were treated by topically ap-plication of ZF of original solution(high dose,n =33)and 1 ∶1 dilution(low dose,n =33)respectively.Hamsters were sacrificed at the 24th week and tissue samples of the left cheek pouch were obtained for the examination of tumor incidence,histopathology and BrdU immunohistochemisty.Results:Gross inspection showed that the incidences of the tumor in positive,low dose and high dose groups were 86.7%,53.6%(P <0.01 )and 50.0%(P <0.01 ),histopathological examination showed that the tumor incidences were 86.7%,78.6% and 64.3%,respectively(P <0.05).High dose of ZF significantly decreased the incidence of hyperplasia , dysplasia and cancer(P <0.05);decreased BrdU-labeling index(P <0.05).Conclusion:Zyflamend may inhibit DMBA induced oral carcinogenesis and such prevention may be related to the effect of the suppression of cell proliferation.
8.Exploration and practice of the Sino-foreign joint graduate education in medicine
Qiaoyan WANG ; Tong ZOU ; Ping WU ; Xuejin LI
Chinese Journal of Medical Education Research 2014;13(12):1249-1252
The Sino-foreign joint graduate education is an important measure of educational innovation.It has been implemented in Capital Medical University since 2009.Regulatory recruitments,strict managements,information system network and creating international exchange opportunities have been engaged in recent years for graduate students,Which wins great effects in Sino-foreign joint graduate education.The practice of the project has improved the graduate students' professional ability,broadened their international vision,and explored the new mode of cultivating creative talents.
9.Effects of Different Ventilation Modes and Parameters on Intragastric Pressure and Digestive Function
Xiaoyun ZHAO ; Yuechuan LI ; Guanhua LI ; Li ZHANG ; Wei JIA ; Lina JIAO ; Xuejin YANG
Tianjin Medical Journal 2013;(7):640-642
Objective To study the effect of different mechanical ventilation modes and parameters on intragastric pressure and digestive function. Methods Forty patients suffered respiratory failure were selected in the study. In different modes and parameters of mechanical ventilation, a multi-channel physiological signal recording device was used to monitor the intra-trachea pressure (ITP), intra-gastric pressure (IGP) synchronously, and the emptying time of stomach, pH value and total bile acid (TBA) concentration in gastric fluid of patients. Results (1) For three types of ventilation mode(PSV,SIMV and CMV), ITP was the lowest in group PSV, the highest was in group CMV and the middle was in group SIMV. With the in-crease in ITP, IGP was also increased. CMV was the most influencing factor for the IGP (P<0.01). In different PEEP values, the greater the PEEP, the higher the ITP. (2) Under mechanical ventilation support, when ITP increased, the emptying time of stomach decreased (P<0.01), the concentration of TBA increased (P<0.05). However, there was no significant change in pH value of gastric fluid (P>0.05). Conclusion Various mechanical ventilation modes and parameter settings induced differ-ent ITP, thereby affecting the IGP and gastric emptying. The digestive function can be promoted by choosing the appropriate mechanical ventilation mode and parameters.
10.Three-dimensional reconstruction combined with minimally invasive titanium plate or lag screw in the repair of complex scapular fractures
Xuejin LI ; Jie XU ; Ying LIU ; Baoyan PEI ; Qun LI ; Yongchong JIANG
Chinese Journal of Tissue Engineering Research 2014;(26):4142-4147
BACKGROUND:Complex scapular fractures were mainly treated by implant fixation. Standard fixation approach (Judet approach) had long incision and big trauma. With the application of spiral CT and three-dimensional reconstruction, minimal y invasive incision could be designed before implant fixation, and then fixation could be finished by physicians. Thus, trauma was reduced and repair effect was elevated. OBJECTIVE:To observe the effects of the three-dimensional reconstruction design combined with titanium plate reconstruction or lag screw for treatment of scapular fractures. METHODS:From February 2007 to January 2012, 33 cases of scapular fractures were enrol ed from Department of Orthopedics, No. 1 Hospital of Qinhuangdao in China. They were scanned by three dimensional reconstruction of CT before implant fixation to identify the regions needed to be repositioned and fixed. Thus, minimal y invasive incision of implant fixation was designed. The dissection of skin, subcutaneous tissue and muscle was reduced. Reposition was performed. Titanium plate and/or lag screw were used for fixation. RESULTS AND CONCLUSION:The operation lasted for 90-130 minutes in 33 patients, with intraoperative blood loss for 300-400 mL. Fracture was total y healed, and the healing time was 2-4 months. The fol ow up lasted for 12-24 months. According to Hardegger standard, there were excellent in 17 cases, good in 12 cases, average in 3 cases and poor in 1 case, with an excellent and good rate of 88%. These results suggested that three-dimensional reconstruction design combined with minimal y invasive incision treatment for scapular fractures showed fewer traumas, can complete the satisfactory fracture reduction and implant fixation, and obtain good repair effect.