1.Uitrasonographic diagnosis of horseshoe kidney of foetus
Ling WEI ; Hejuan GUO ; Xuehong JIN ; Yanqing LI ; Xiaohong WANG
Chinese Journal of Primary Medicine and Pharmacy 2008;15(2):256-257
Objective To explore the horseshoe kidney of prenatal ultrasonography for detecting birth defects.Methods A total of 3260 women during 22~42 gestational weeks underwent real-time color Doppler ultrasongraphy to find out fetal mati kidney.All the cases were tracked within two month after delivery.Results In all 3260 pregnant women,104 cases were diagnosed on ultrasonography of 100%accordance with clinical diagnosis.Conclusions A systemic prenatal ultrasonographic examination in the second-trimester pregnancy is important for prenatal diagnosis of congenital malformations,which play a very significant role in decreasing fetal birth defects and improving new born population quality.
2.Breastfeeding behavior among infants aged 6-24 months and difference between urban and rural areas in Southwest China
Lujiao HUANG ; Ming LI ; Li RUI ; Xiaohong SUN ; Xuehong PANG ; Lan ZHOU ; Guo ZENG
Chinese Journal of Perinatal Medicine 2013;16(7):410-415
Objective To understand the status and difference of breastfeeding behavior in urban and rural areas of Southwest China.Methods From March to July in 2011,3659 infants aged 6-24 months were selected by stratified cluster randomized sampling method in urban and rural areas of three provinces of Southwest China (Sichuan,Yunnan and Guizhou),including 1801 (49.2%)infants from urban areas and 1858(50.8%) from rural areas.Basic information of these infants,their families and breastfeeding was obtained by a questionnaire for the mothers or baby-carers.Descriptive analysis and survival analysis (Kaplan-Meier method) were used to describe breastfeeding behavior.Chi-square test and Log-Rank test were used to identify the differences of breastfeeding behavior between urban and rural areas.Results Early breastfeeding initiation rate within one hour after birth was 10.7%(355/3315),and the numbers of urban and rural areas were 12.3%(198/1604) and 9.2% (157/1711),respectively,x2 =8.691,P<0.05.Totally,20.3%(725/3575) of all infants were initially fed by breast milk after delivery,and 25.1% (440/1754) in urban areas and 15.7 % (285/1821) in rural areas,x2 =49.192,P<0.05.The exclusive breastfeeding rate and breastfeeding rate within four months after birth were 35.5% (27.4% in urban and 43.6% in rural areas,x2=88.678,P<0.05)and 76.2% (68.5% in urban and 84.3% in rural areas,x2 =124.702,P<0.05),respectively.However,the exclusive breastfeeding rate and breastfeeding rate within six months after birth reduced to 11.3% (7.9% in urban and 14.4% in rural areas,x22 =18.001,P<0.05) and 65.0% (54.0% in urban and 76.3% in rural areas,x2 =199.662,P<0.05),respectively.The median breastfeeding duration was 8.0 months (7.0 months in urban and 9.0 months in rural areas,x2 =96.780,P< 0.05).The most common reason of weaning was insufficient breast milk which accounting for 48.7 % of families [56.9% (1161/2385) in urban and 39.9%(462/1157) in rural areas,x2=68.840,P<0.05].Conclusions In Southwest China,intervention program should be implemented to improve the breastfeeding status.Breastfeeding behaviors are different between urban and rural areas in Southwest China.The initiation of breastfeeding in urban area is better,but the sustainability of breastfeeding is better in rural area.
3.A clinical study on the treatment of mucocele by bleomyin A5 combined with phosphorus-32 colloid.
Xiaoxi PANG ; Xuehong CHEN ; Jingui HU ; Jiangyan LIU ; Xiaohui WANG ; Fangzhou GUO
Chinese Journal of Stomatology 2015;50(10):624-626
OBJECTIVETo evaluate the effect of bleomyin A5 combined with phosphorus-32 colloid in the treatment of mucocele.
METHODSA total of 214 patients divided into three groups, bleomyin A5 (50 cases), phosphorus-32 colloid (50 cases) and bleomyin A5 combined with phosphorus-32 colloid (114 cases).
RESULTSThe efficacy of bleomyin A5 group, phosphorus-32 colloid group, and bleomyin A5 combined with phosphorus-32 colloid group was 84% (42/50), 82% (41/50) and 98% (112/114), respectively. There were significant difference in efficacy among the three groups (P < 0.05). The phosphorus-32 colloid group and the bleomyin A5 group had no significant difference in efficacy (P > 0.05).
CONCLUSIONSThe independent use of bleomyin A5 and phosphorus-32 colloid is effective, but the combined use of the two methods is more effective.
Bleomycin ; analogs & derivatives ; therapeutic use ; Colloids ; Combined Modality Therapy ; methods ; Humans ; Mucocele ; therapy ; Phosphorus ; Phosphorus Radioisotopes ; therapeutic use ; Treatment Outcome
4.Clinical study for treating steroid-resistant nephrotic syndrome by the methods of Shugan-Yiqi-Yangyin
Xuehong ZHANG ; Zhanjun GUO ; Cangfeng LAN
International Journal of Traditional Chinese Medicine 2018;40(3):209-213
Objective To observe the clinical effect of the method of Shugan-Yiqi-Yangyin treatment for the steroid-resistant nephrotic syndrome (SRNS). Methods A total of 80 patients with SRNS were divided into 2 groups by random number table method, 40 in each group. The control group received glucocorticoids combined with Tripterygium Glycosides;and the treatment group received Shugan-Yiqi-Yangyin on the basis of the control group, 3 month as a course. The 24 h urine protein quantitative (propagated), plasma albumin, blood lipid (total cholesterol, triglycerides), hemorrheology, blood urea nitrogen (BUN), creatinine (Cr), urinary inhibition C (Cys C) were detected before and after the treatment of two groups, and the clinical effect was compared. Results The total effective rate of the treatment group was 92.50% (37/40) and 82.50% (33/40) in the control group, and the difference was statistically significant (Z=-1.966, P<0.05). After the treatment, the 24 hPRO (1.03 ± 0.64 mg vs.2.81 ± 1.43 mg,t=3.025),Cys C(0.35 ± 0.41 mg/L vs.0.76 ± 0.51 mg/L, t=3.058) of the treatment group was significantly lower than those of the control group(P<0.05).The Alb(34.88 ± 2.17 mg vs. 31.69 ± 2.05 mg, t=2.986) of the treatment group was significantly higher than this of the control group (P<0.05), After treatment,the whole blood high shear viscosity(7.84 ± 1.42 mPa?s vs.8.94 ± 1.38 mPa?s,t=3.160),the whole blood low shear viscosity(4.55 ± 0.37 mPa?s vs.5.02 ± 0.44 mPa?s,t=3.825),plasma viscosity(1.33 ± 0.10 mPa?s vs.1.95 ± 0.26 mPa?s,t=2.981),hematocrit(0.28 ± 0.03 vs.0.34 ± 0.03,t=2.993),fibrinogen(3.96 ± 0.57 g/L vs.4.52 ± 0.47 g/L,t=4.863)of the treatment group were significantly lower than those of the control group(P<0.05).The TC(5.04 ± 1.72 mmol/L vs.6.99 ± 1.06 mmol/L,t=3.67),TG(1.4 ± 0.64 mmol/L vs.2.02 ± 0.31 mmol/L, t=3.040) of the treatment group were significantly lower than those of the control group (P<0.05). Conclusions The Shugan-Yiqi-Yangyin treatment for SRNS can obviously improve the symptoms,reduce the side effects of hormone of antagonism. The possible mechanisms are to restore kidney function, improve blood viscosity and lower blood lipid levels.
5.Relationship between complementary feeding behaviors and anemia for infants and young children in Sichuan, Yunnan and Guizhou province of China.
Mingzhe YANG ; Li RUI ; Ming LI ; Xiaohong SUN ; Xuehong PANG ; Lan ZHOU ; Guo ZENG
Chinese Journal of Preventive Medicine 2014;48(7):592-595
OBJECTIVETo examine the relationship between complementary feeding behaviors (CFB) and anemia for infants and young children in Sichuan, Yunnan and Guizhou province of China.
METHODSA total 3 410 children aged 6-24 months were recruited from 12 survey sites in the urban and rural areas of Sichuan, Yunnan and Guizhou provinces by stratified random cluster sampling in 3 age groups (6-8 months, 9-11 months and 12-24 months) from March to July in 2011. The information of CFB for them was collected through a specific questionnaire. According to the comprehensive evaluation method of CFB(including content of food preparation and selection, caregivers' behavior, infants' behavior, feeding environment and environmental hygiene), the scores of CFB were calculated and grouped as low ( < 60% of total score), moderate (60%-80% of total score) and high level ( > 80% of total score). Twenty microliter of fingertip blood was extracted to measure the hemoglobin concentration and anemia rate was calculated. Distribution of CFB level and rate of anemia were compared between urban/rural areas and different age groups. Difference of anemia rate for infants and young children between low/moderate/high CFB level groups was compared.
RESULTS8.0% (273/3 410) of the children were in low CFB level group, and 56.9% (1 940/3 410) and 35.1% (1 197/3 410) in moderate and high CFB level group respectively. The difference of CFB levels between urban and rural areas was significant (Z = -21.17, P < 0.05), the proportion of high level in urban area was 53.0% (829/1 565) , which was higher than that in rural area (20.0% (368/1845) ). The difference of CFB levels between different age groups was also significant (H = 43.82, P < 0.05). The proportion of high level decreased by increasing age, which was 41.0% (417/1 017) and 29.9% (389/1 300) in 6-8 months and 12-24 months respectively. The average hemoglobin concentration for infants was (119.3 ± 13.8)g/L, and the total anemia rate was 22.4% (765/3 410) . The hemoglobin concentration for infants in urban area ( (123.3 ± 11.3) g/L) was higher than rural area ((115.9 ± 14.8) g/L) (t = 16.75, P < 0.05) and the rate of anemia in urban area (10.5% (165/1 565)) was lower than that in rural area (32.5% (600/1845) ) (χ² = 235.03, P < 0.05) significantly. The rate of anemia was decreased by increasing CFB level(χ² = 73.94, P < 0.05). The rate of anemia in the low CFB level group was the highest (33.7% (92/273) ) while in the high CFB level group was 14.5% (174/1 197), which was the lowest.
CONCLUSIONThe level of complementary feeding behavior for infants and young children in Sichuan, Yunnan and Guizhou province of China is relatively low and their prevalence of anemia is relatively serious. Complementary feeding behavior is closely associated with anemia for infants and young children.
Age Factors ; Anemia ; China ; epidemiology ; Humans ; Infant ; Infant Nutritional Physiological Phenomena ; Prevalence ; Rural Population ; Surveys and Questionnaires ; Urban Population
6.Genetic polymorphism and relationship of 24 Y-STR loci among three ethnic minorities from Guizhou.
Xuehong GUO ; Yan HE ; Xiuxiu ZHANG ; Chanjuan WANG ; Ting ZHANG ; Zhizhong GUAN
Chinese Journal of Medical Genetics 2018;35(4):595-599
OBJECTIVETo study the distribution of haplotypes of Y-chromosomal short tandem repeats (Y-STR) loci among three ethnic minorities from Guizhou, China.
METHODSTwenty four Y-STR loci of 174 unrelated males were amplified with a Microreader(TM)24Y Direct ID System kit. Capillary electrophoresis was carried out on an ABI 3100 Genetic Analyzer, and the data was analyzed with GeneMapper software.
RESULTSSeventy six haplotypes were identified for the 24 Y-STR loci among the three ethnic minorities, including 13 from the Qiangs, 35 from the Manchurians, and 28 from the Shes, with the corresponding Haplotype Diversity (HD) being 0.7327, 0.9578, and 0.9344. Genetic distance between the Shes and Qiangs was relatively close, whilst that for Manchurians was relatively far.
CONCLUSIONAnalysis of the genetic characteristics and relationship of the three ethnic minorities from Guizhou can provide a reference for the study of their origin, evolution and patrilineal fusion.
7.Study on frequency of 9 bp sequence deletion of mithochondrial DNA in three ethnic nationalities of Guizhou Province
Xuehong GUO ; Yan HE ; Wangde ZHANG ; Chanjuan WANG ; Ting ZHANG ; Zhizhong GUAN
Chongqing Medicine 2017;46(33):4702-4704
Objective To study the frequency of 9 bp sequence deletion of mithochondrial DNA in three ethnic nationalities of Guizhou Province .Methods A total of 183 male blood samples were randomly extracted from Miao nationality (69 cases) in Leishan County ,Shui nationality (44 cases) and Buyi nationality (70 cases) in Libo County .Polymerase chain reaction(PCR) and di-rect sequencing were used to detect the mithochondrial DNA 9 bp sequence deletion .Results The standard type ,deleting type and 3 type were found in the samples of 3 ethnic nationalities in Guizhou Province ,the highest deletion frequency was Shui nationality (40 .91% ) in Libo County ,1 cases of 3 type was detected in Miao nationality of Leishan County ,and the mtDNA 9 bp deletion fre-quency had no statistical difference among 3 ethnic nationalities(P>0 .05) .Conclusion The frequency of mtDNA 9 bp deletion is different among three native minorities ,the genetic variation in Shui nationality is larger ,compared with Miao nationality genetic re-lationship ,Shui nationality has a relatively closer affinity with Buyi nationality .