1.DISTRIBUTION AND NORMAL VALUE OF FREEERYTHROCYTE PROTOPORPHYRIN IN NON-IRONDEFICIENT INFANTS AND CHILDREN
Wei ZHANG ; Qinghua ZHU ; Xuehong DENG
Acta Nutrimenta Sinica 1956;0(02):-
0.05, but there was a larger deviation with Model 930.
2.The mediating effect of self-evaluation on boredom proneness and aggression in medical students
Juan XU ; Xuehong DENG ; Miaomiao LIU ; Qiuli LI ; Xiuying DAI
Chinese Journal of Behavioral Medicine and Brain Science 2014;23(7):644-647
Objective To explore the relationship among boredom proneness,core self-evaluation and aggression in medical students and to provide clues and evidence for preventing aggression and their relevant interventions.Methods The Boredom Proneness Scale for College Students(C-BPQ),Chinese Version of Buss & Perry Aggression Questionnaire (AQ-CV)and Core Self-evaluations Scale were employed to investigate 1667 medical students in one medical university in Ningxia.Results There were significant differences between high and low boredom proneness groups in core self-evaluations,total aggression score and each factors (core self-evaluations:(29.67±5.10) vs (41.67±4.64),AQ-CV scores:(36.43±17.18) vs (17.58±12.45),physical aggression:(31.62 ±20.46) vs (17.02 ±15.28),verbal aggression:(37.44±19.03) vs (24.68±17.14),anger:(40.93±22.32) vs (18.85±16.86),hostility:(37.34± 19.41) vs (14.86± 13.57),self-aggression:(35.47 ±21.66) vs (13.57± 14.28),all P<0.001).There were positive correlation among total score of boredom proneness,internal and external stimuli dimensions,total score of AQ-CV and each factors (P<0.001) and negative correlation between total score of boredom proneness and core self-evaluation(P<0.001).There were negative correlation among core self-evaluation score,AQ-CV scores and each factor(P<0.001).Regression analysis showed that boredom proneness and core self-evaluation could predict the aggression to a certain extent (P<0.01).Core self-evaluation played a mediating role between boredom proneness and aggression taking 48.25% proportion of the total effect of the mediation.Conclusion Boredom proneness is closely related to aggressive behavior.Core self-evaluation plays a mediating role between boredom proneness and aggression.
3.Brain Characteristics of Open Spina Biifda on Ultrasound at 11-13+6 Weeks of Gestation
Yuanming HUANG ; Dongping HUANG ; Ziyu WU ; Xuehong DENG ; Yaojia LIANG ; Yaoyuan LIANG
Chinese Journal of Medical Imaging 2015;23(8):615-617
Purpose To explore the clinical value of ultrasound in charactering brain anomalies in open spina bifida at 11-13+6 weeks of gestation.Materials and Methods Abdominal and transvaginal ultrasound was performed in 125 cases of normal fetus and 4 cases of confirmed open spina bifida at 11-13+6 weeks of gestation to compare the morphology of intracranial translucency (IT), diencephalon and midbrain.Results Fetal IT was readily recognized in all 125 normal cases, with diencephalons and midbrain showing number 8 shape. In 4 cases of open spina bifida, fetal IT cannot be identified, and the expected 8 shape of diencephalon and midbrain was distorted.Conclusion Fetal brain characteristics including intracranial translucency and the shape of diencephalon and midbrain in 11-13+6 weeks gestation are valuable ultrasound screening indicators for open spina bifida.
4.Panax notoginseng in treatment of myocardial ischemia/reperfusion injury and its application prospect
Guang LI ; Xiaoyan XING ; Meishuang ZHANG ; Jinjin SHI ; Xuehong DENG ; Guibo SUN ; Xiaobo SUN
Chinese Pharmacological Bulletin 2015;(10):1340-1344
Myocardial ischemia/reperfusion injury ( MI/RI) is a pathophysiological phenomenon commonly seen during thromboly-sis, percutaneous transluminal coronary angioplasty ( PTCA ) , and coronary artery bypass grafting ( CABG ) . It is defined as restoration of blood flow to a previously ischemic region followed by complex pathological events leading to tissue injury greater than the original ischemic insult. Many experimental interven-tions have been reported to protect the ischemic myocardium in experimental animals; however, with the exception of early reperfusion, none has been translated into clinical practice. The root of Panax notoginseng ( Burk. ) F. H. Chen ( PN) is one of the iconic herbs in traditional Chinese medicine. Traditional pharmacopeia recommended it among the most efficacious herbs for‘promoting blood circulation ’ and hemostasis. Inspired by this, in the last decade, a large number of modern investigators made substantial efforts to search the PN activities against a vari-ety of MIRI. The systematic review was performed according to the protecting drug of the MIRI development guidelines.
5.Th1/Th2 imbalance in ischemia-reperfusion injury and the application prospects of traditional Chinese medicine with multi-target effect
Xuehong DENG ; Xiaoyan XING ; Guang LI ; Meishuang ZHANG ; Jinjin SHI ; Guibo SUN ; Xiaobo SUN
Chinese Pharmacological Bulletin 2015;(9):1185-1188,1189
The damage of tissue increases dramatically after reperfusion of blood supply to ischemic tissues.Immune response is one of the key reasons of ischemia-reperfusion injury.Th1 /Th2 generally stays balanced in normal states.Under the envi-ronment of ischemia reperfusion,Th1 /Th2 shifting let Th1 domi-nant to mediate cellular immunity.Excessive immune reaction may cause cell apoptosis and tissue damage.Recent studies showed that induction of transferring Th1 dominant to Th2 domi-nant was feasible for the treatment of ischemia-reperfusion inju-ry.With the progress of modern drug development paradigm“multi-composition,multi-target”,Chinese medicine has advan-tages in treating complex diseases.This paper summarizes the research of the relationship between Th1 /Th2 imbalance and is-chemia-reperfusion injury,together with the prospects of tradi-tional Chinese medicine with multi-target effect in ischemia-reperfusion injury.
6.Multiple organ dysfunction syndrome due to ingestion of fish gall bladder.
Yuelin DENG ; Guilin XIAO ; Yiqiang JIN ; Xuehong LUO ; Xinke MENG ; Jie LI ; Zhang AO ; Jenming XIAO ; Liping ZHOU
Chinese Medical Journal 2002;115(7):1020-1022
OBJECTIVETo investigate changes in renal function, urine N-acetyl-beta-D-glucosaminidase enzyme (N-AG),liver function, myocardial enzymes, the pathology of renal damage and the mechanism of acute renal failure (ARF) associated with fish gall bladder poisoning.
METHODSEleven patients with acute fish gall bladder poisoning were consecutively admitted to our hospital from September 1997 to October 1999. Renal function, urine N-AG enzyme, liver function, and myocardial enzymes were assayed before and after treatment. One patient consented to a kidney biopsy and the pathology of renal damage was observed under light and electron microscopes.
RESULTSAll patients had multiple organ dysfunction syndrome (MODS) and 11 patients suffered from ARF. Ten patients had liver dysfunction, ten patients had poisonous myocarditis, and 8 patients had gastrointestinal dysfunction. Renal function, urine N-AG enzyme, liver function, and myocardial enzymes were significantly improved after treatment compared with those of before treatment (P < 0.05). Kidney biopsy showed that the main damage site was the proximal renal tubule. All eleven patients recovered and were discharged from the hospital.
CONCLUSIONSIngestion of fish gall bladder leads to kidney damage, as well as liver, heart and gastrointestinal tract injury. The mechanism of acute renal function failure is the serious tubular damage, confirming the location of kidney damage. Necrosis of the proximal tubules plays an important role in the development of ARF. Immediate hemodialysis is the most effective treatment.
Adult ; Aged ; Animals ; Female ; Fishes ; Foodborne Diseases ; etiology ; Gallbladder ; Humans ; Male ; Middle Aged ; Multiple Organ Failure ; etiology