Objective To explore the influence of the noviciate mode of the pregnant and lying-in woman all-the-way tracking on midwifery students' professional attitude and capability development. Methods Eight-one junior college midwifery students of grade 2013 were included. They were divided into the control group (n=42, one class) and the observation group (n=39, the other class) with the convenience sampling method. The traditional noviciate mode was used in the control group and the all-the-way tracking noviciate mode was used in the observation group. The students' performance in the two groups before and after the noviciate was compared according to the nursing student professional identify questionnaire, the clinical thinking scale and the supportive communication scale.Results After the noviciate,the professional identity, the critical thinking ability and the supportive communication ability of the students were (2.65±0.41),(3.58±0.43) and (3.87±0.18) in the observation group,respectively, and (2.39±0.43),(3.07±0.32) and (3.38±0.15) in the control group, respectively. All the scores in the observation group were significantly higher than those in the control group (t=2.66,6.49,12.83;P<0.01).Conclusions The pregnant and lying-in woman all-the-way tracking noviciate can increase midwifery students' professional identity, which is helpful for the development of the studnets'comprehensive ability.

Objective:To investigate the clinical effect of self-designed modified rhomboid flap in repairing rhomboid, round, and teardrop-shaped wounds on the face.Methods:A retrospective observational study was conducted. From August 2018 to April 2020, 30 patients with facial lesions admitted into Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine and the People's Hospital of Jianchuan County in Yunnan province met the inclusion criteria, including 16 males and 14 females, aged 23 to 88 years. The wound area ranged from 1.0 cm×1.0 cm to 7.0 cm×5.0 cm, with 10 cases of rhomboid wounds, 12 cases of round wounds, and 8 cases of teardrop-shaped wounds. The self-designed modified rhomboid flaps were applied to repair the wounds and after that, the patients were followed up for 1 to 18 months to record the survival of flaps, wound tension, scar formation and complications after surgery.Results:No necrosis or blackening was observed at the tip of the flaps after surgery. All the flaps survived and the wounds healed well with little tension, minimal scars, and no complications.Conclusions:The self-designed modified rhomboid flap is especially suitable for facial wounds with multiple important organs, multiple anatomical subunits, and areas with large changes in soft tissue tension, which can reduce not only the rotation of the flap, but also unnecessary excision of normal skin and soft tissue.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause acute respiratory distress syndrome, hypercoagulability, hypertension, and multiorgan dysfunction. Effective antivirals with safe clinical profile are urgently needed to improve the overall prognosis. In an analysis of a randomly collected cohort of 124 patients with COVID-19, we found that hypercoagulability as indicated by elevated concentrations of D-dimers was associated with disease severity. By virtual screening of a U.S. FDA approved drug library, we identified an anticoagulation agent dipyridamole (DIP) , which suppressed SARS-CoV-2 replication . In a proof-of-concept trial involving 31 patients with COVID-19, DIP supplementation was associated with significantly decreased concentrations of D-dimers ( < 0.05), increased lymphocyte and platelet recovery in the circulation, and markedly improved clinical outcomes in comparison to the control patients. In particular, all 8 of the DIP-treated severely ill patients showed remarkable improvement: 7 patients (87.5%) achieved clinical cure and were discharged from the hospitals while the remaining 1 patient (12.5%) was in clinical remission.