1.Clinical investigation and analysis of chronic diseases and geriatric syndromes in elderly inpatients
Cuilian LU ; Hui ZHANG ; Xuecai FU ; Hong JI
Chinese Journal of Geriatrics 2019;38(8):913-916
Objective To investigate and analyze the chronic diseases and geriatric syndromes in elderly inpatients.Methods A total of 227 elderly patients undergoing the comprehensive geriatric assessment admitted into geriatric ward of our hospital from June to December in 2018 were retrospectively analyzed in this case-control study.The patients were divided into two groups aged 80-90 years(n=137)and 65-79 years(n=90).The prevalence of chronic diseases and distribution of geriatric syndromes were compared between the two groups.Results Among 227 patients,the top five chronic diseases were primary hypertension (155 cases,68.3 %),cerebrovascular diseases (108 cases,47.8%),coronary heart disease(103 cases,45.4 %),osteoarthrosis (9 cases,39.2 %) and type 2 diabetes mellitus (79 cases,34.8%).The prevalence of chronic diseases and geriatric syndromes showed an increased tendency along with ageing in elderly patients.The incidence rate of malnutrition,nutritional risk,cognitive disorders,poor vision,hearing loss,fecal and urinary incontinence and constipation were higher in the group aged 80-90 years than in the group aged 65-79 years (P<0.05).The decreases of activities of daily life and instrumental activities of daily life,and fragile were more severe in the group aged 80-90 years than in the group aged 65-79 years(P>0.05).No significant difference was found between the two groups in the incidences of multidrug use,mood disorder,sleep disorder,chronic pain and falls.The prevalence of chronic diseases was positively correlated with the prevalence of geriatric syndromes(r =0.339,P <0.01).Conclusions Along with ageing in elderly inpatients,the number of chronic diseases is increased,geriatric syndromes are more obvious,and the function significantly declines in elderly inpatients.Elderly patients should receive the comprehensive geriatric assessment,in order to timely identify and intervene these geriatric problems.
2.Effect of controlled hypotension on predicting transfusion response and threshold of stroke variability in hypertensive patients undergoing robotic hepatobiliary surgery.
Zhe XU ; Xuecai LÜ ; Qiang FU ; Yi LIU ; Rong LIU ; Weidong MI
Journal of Central South University(Medical Sciences) 2019;44(4):419-425
To investigate the effect of controlled hypotension by urapidil on the predictive accuracy and diagnostic threshold of stroke volume variation (SVV) in hypertensive and non-hypertensive patients undergoing robotic hepatobiliary surgery.
Methods: Eighty patients undergoing robotic hepatobiliary surgery under general anesthesia were divided into a hypertension group (n=25) and a non-hypertension group (n=38) according to whether or not essential hypertension was present (excluding some cases that didn't meet requirements). The pump speed was at 6.0-7.0 µg/(kg﹒min), and the range of hypotension was between 10%≤Δ systolic blood pressure (SAP)≤20%. Volume loading test was performed after artificial pneumoperitoneum was established in reverse-Trendelenburg position. Hemodynamic indexes including heart rate (HR), SAP, cardiac output (CO), cardiac index (CI), stroke volume (SV), stroke volume index (SVI) and SVV were recorded before and after infusion. Then the receiver operating characteristic (ROC) curves of SVV was drawn to determine the accuracy and diagnosis of SVV in predicting volume status in hypertensive and non-hypertensive patients after anti-Trendelenburg posture and pneumoperitoneum.
Results: In the patients with controlled hypotension by urapidil, the area under the ROC curve of SVV in the hypertension group was 0.974, the diagnostic threshold was 13.5%, the ROC curve of SVV in the non-hypertension group was 0.832, and the diagnostic threshold was 15.5%.
Conclusion: SVV can accurately predict the volume status in the hypertension group and the non-hypertension group after controlled hypotension in the anti-Trendelenburg position and fixed pneumoperitoneal pressure, and the SVV diagnostic threshold in the non-hypertensive group is higher than that in the hypertensive group.
Biliary Tract Diseases
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surgery
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Blood Pressure
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Cardiac Output
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Fluid Therapy
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Hemodynamics
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Humans
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Hypotension, Controlled
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Liver Diseases
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surgery
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ROC Curve
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Robotic Surgical Procedures
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Stroke
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Stroke Volume