1.Rosuvastatin escape in a Chinese elderly with hyperlipidemia.
Xu-Jiao CHEN ; Lei CHENG ; Jiao-Jiao CHU ; Jia CHEN ; Xiao-Fang TANG ; Xue-Feng ZHANG
Chinese Medical Journal 2013;126(18):3578-3579
2.Isolation and Identification of Osmotolerant Yeast from "Swollen Can" Soy Sauce
You-Sheng OUYANY ; Xiao-Bao XIE ; Jiao-Di CHEN ; Hua XUE ; Yi-Ben CHEN ;
Microbiology 1992;0(04):-
Three osmotolerant yeasts were isolated from three batches of "swollen can" soy sauce produced by a Guangdong condiment plant. These strains grew faster in the media containing 50%~60% glucose or 15% NaCl than in common yeast media. The three yeasts were identified as Pichia etchellsii by using morphological characteristics, physiological and biochemical tests.
3.Effect of Point-of-care Hemoglobin/Hematocrit Devices and Autologous Blood Salvage on Reduction of Perioperative Allogeneic Blood Transfusion.
Wei-Yun CHEN ; Xue-Rong YU ; Jiao ZHANG ; Qing YUAN ; Yu-Guang HUANG
Chinese Medical Sciences Journal 2016;31(2):83-88
Objective To evaluate the effect of point-of-care hemoglobin/hematocrit (POC HGB/HCT) devices and intraoperative blood salvage on the amount of perioperative allogeneic blood transfusion and blood conservation in clinical practice.Methods A total of 46 378 medical records of 22 selected hospitals were reviewed. The volume of allogeneic red blood cell and plasma, number of patients transfused, number of intraoperative autologous blood salvage, total volume of autologous blood transfusion, and amount of surgery in the year of 2011 and 2013 were tracked. Paired t-test was used in intra-group comparison, while t-test of two isolated samples carried out in inter-group comparison. P<0.05 was defined as statistically significant difference.Results In the hospitals where POC HGB/HCT device was used (n=9), the average allogeneic blood transfusion volume per 100 surgical cases in 2013 was significantly lower than that in 2011 (39.86±20.20 vs. 30.49±17.50 Units, t=3.522, P=0.008). In the hospitals without POC HGB/HCT meter, the index was not significantly different between 2013 and 2011. The average allogeneic blood transfusion volume was significantly reduced in 2013 than in 2011 in the hospitals where intraoperative autologous blood salvage ratio [autologous transfusion volume/(autologous transfusion volume+allogeneic transfusion volume)] was increased (n=12, t=2.290, P=0.042). No significant difference of the above index was found in the hospitals whose autologous transfusion ratio did not grow.Conclusion Intraoperative usage of POC HGB/HCT devices and increasing autologous transfusion ratio could reduce perioperative allogeneic blood transfusion.
4. Vaccine strategies in prevention and treatment of atherosclerosis
Journal of Shanghai Jiaotong University(Medical Science) 2018;38(1):108-111
Atherosclerosis is an immune-mediated inflammatory disease of the arterial wall, with both the innate and adaptive immune systems responding to many endogenous and exogenous antigens. Both proatherogenic as well as atheroprotective roles have been identified for the immune system in atherosclerosis. Hence, it is conceivable that an immuno-modulatory strategy via active immunization against many of these antigens could potentially alter the natural history of atherosclerosis. Cholesterol ester transfer protein (CETP) plays an important role in lipid metabolism, suggesting it might prevent atherosclerosis. This review discusses the recent advances of vaccine targeting the development of atherosclerosis, mainly about the CETP targeting vaccines.
5.The effect of probiotic on reducing ventilator-associated pneumonia incidence in sepsis patients with mechanical ventilation
Jiao CHEN ; Ling JIA ; Jinghui YANG ; Xiang XUE ; Jianqin CAI ; Weixiao XU ; Wei ZHAO
Chinese Journal of Emergency Medicine 2021;30(2):179-182
Objective:To explore the effect of probiotics on reducing ventilator-associated pneumonia (VAP) in sepsis patients.Methods:A total of 94 cases were randomly (random number) divided into the probiotic group ( n = 46) and the control group ( n = 48). All of the patients were given enteral nutrition therapy by nasogastric tube within 24-72 h after admission. And patients in the probiotic group were given live combined bifidobacterium, lactobacillus and enterococcus powder besides the regular therapy. The incidence of VAP, bacteremia, mortality, mechanical ventilation time and length of ICU stay were compared between the two groups. Results:Compared with the control group, the incidences of VAP and bacteremia in the probiotics group were significantly lower (χ 2=4.763, P=0.029; χ 2=4.438, P=0.035). There were no significant differences in 28-day mortality and the length of hospital stay between the two groups (χ 2=2.02, P=0.167; t=1.29, P=0.208). Mechanical ventilation time in the probiotics group was significantly shorter than that in the control group ( t=2.16, P=0.038). The Log-Rank test showed that the time of VAP-free in the probiotics group was significantly longer than that in the control group ( P < 0.05). After adjusting for APACHEⅡ score and age, COX proportional risk model analysis showed that the RR values of the probiotics group and the control group for 28-day VAP were 0.18 (95% CI: 0.12-0.74, P=0.025) and 0.21 (95% CI: 0.19-0.95, P=0.042), respectively. Conclusions:Probiotics treatment can reduce the incidence of VAP in sepsis patients.
6.The Design of Measure and Control System for Composite Treating Instrument of Gastrointestinal Cancer
LING AN ; Xiao-Lin WANG ; Xue-Su FENG ; Ya-Zhu CHEN
Chinese Journal of Medical Instrumentation 2001;25(3):128-129,127
This paper introduced a composite method of treating gastrointestinal tract cancer-thermo-chemotherapy.A complete set of intelligentialized real-time measure and control system was well designed. The experiment result showed that this system has a stable performance and good real-time.
7.Development of the combined tumor therapeutic equipment.
Qi CHEN ; Bin XIONG ; Ya-zhu CHEN ; Xue-su FENG
Chinese Journal of Medical Instrumentation 2002;26(2):105-195
This paper describes the development of the combined tumor therapeutic equipment based on the theory of 1 + 1 = 3 or 1 + 1 > 3 tumor combined treatment synergism. It has become a promising and valuable method dealing with cancer tumors for its good adaptability, better effectiveness and convenience. The therapeutic equipment is combined with PC and MS windows operation system, and adopts intellectual temperature control device, which realizes homogeneous and smooth heating to intracavity tumor focus and automatic processing and statistical management of all case data. The equipment works stably and is of great value in clinical applications.
Algorithms
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Combined Modality Therapy
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Equipment Design
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Humans
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Hyperthermia, Induced
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instrumentation
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methods
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Information Storage and Retrieval
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Male
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Microcomputers
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Middle Aged
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Rectal Neoplasms
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therapy
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Software
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Therapy, Computer-Assisted
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instrumentation
9.TCM Syndrom Type Distribution Characteristics for 186 Cases of AIDS Dementia Complex
Xue ZHANG ; Ziqiang JIANG ; Lihua CHEN ; Yan SUN ; Xuan YANG ; Shuangli WANG ; Yonghui AN ; Xiaohua ZHANG ; Min JIAO ; Jing ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(3):14-17
Objective To study the relationship between different syndromes of AIDS dementia complex (ADC) and different disease severity, age, CD4+ T cell count and infection. Methods Totally 186 patients with ADC were classified into different syndrome types, and the distribution in different degree of disease, different age, different CD4+T cell count and different routes of infection was analyzed. Results There were 48, 51, 15, 37 and 35 cases of deficiency of kidney and marrow, yin deficiency of liver and kidney, deficiency of heart and spleen, syndrome of phlegm obstruction, syndrome of qi deficiency and blood stasis, respectively. Moderate and severe degrees with yin deficiency of liver and kidney were more common. There was statistical significance in the distribution of different syndromes in different degree of disease (χ2=82.495, P=0.000). Deficiency of kidney and marrow, yin deficiency of liver and kidney were more common in different age groups. The distribution of the syndrome types in different age groups was statistically significant (χ2=72.710, P=0.000), the patients were mainly in two age groups of>50–60 years old and>60 years old. The distribution of the syndrom types in diffenrent CD4+T cell count stratum was statistically significant (χ2=66.778, P=0.000). Blood pathway infection mainly included deficiency of kidney and marrow and syndrome of qi deficiency and blood stasis, sexual pathogens mainly yin deficiency of liver and kidney. Conclusion CD4+T cells layers, age group, progression of disease and transmission way are the influencing factors of syndrom type.
10.Recognition of Gaussian pixelate Chinese character based on simulated prosthetic vision.
Ji ZHAO ; Xue-Quan LV ; Chun-Rui HUANG ; Pan-Pan CHEN ; Xin-Yu CHAI
Chinese Journal of Medical Instrumentation 2009;33(5):317-319
In this paper, Gaussian pixelate Chinese character processing software is designed, and HMD is used to realize the recognition experiment for pixelate Chinese characters based on simulated prosthetic vision. The structure of recognition system, software design and the experiment for determining Gaussian width (sigma) are presented. It is shown that when sigma is 0.235, the recognition program is the best.
Equipment Design
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Image Processing, Computer-Assisted
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Language
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Prostheses and Implants
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Software Design
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Visual Perception