Retinal ischemia-reperfusion injury (RIRI) is a common pathological and physiological clinical oculopathy,which can occur in retinal artery and vein occlusion,diabetic retinopathy and acute angle-closure glaucoma.The resulting ischemia can cause cell metabolic dysfunction,serious retinal damage and descending visual function.RIRI is the result of multiple factors.The currently accepted hypotheses mainly include the injury effect of oxygen-derived free radicals,intracellular calcium overload,the action of leucocyte and apoptosis.However the protection and treatment research in the RIRI is limited.The present paper reviews the progression in the drug intervention of RIRI.

Children with plastic bronchitis,characterized by unknown origin,insidious onset,rapid progress,severe symptom and high mortality,is a relatively rare disease.Also,it is difficult to diagnose and treat with plastic bronchitis characterized by marked airway obstruction,via the formation of large gelatinous or rigid airway cast.It is associated with certain diseases including bronchial asthma,cystic fibrosis,accompanied with acute chest syndrome with sickle cell disease,congenital heart disease and bacterial and viral respiratory infection.Clinicians should be aware of this disease,and early bronchoscopy should be intervened.

Fatigue is one of the most common complaints in cancer patients that profoundly affects all aspects of quality of life.However,cancer-related fatigue remains under recognized and poorly treated.This rcview has been conducted with the causes and potential treatments of fatigue in cancer patients.The methods for evaluating fatigue,and possible therapeutic options are also discussed.

Dermatovenereology have developed rapidly in fields including genodermatology, dermatological epidemiology, skin immunology, infectious skin diseases, clinical diagnosis, drug treatment, light therapy, and sexually transmitted diseases in recent years. Meanwhile, many skin diseases and a few venereal diseases still lack effective ways of treatment and control. More efforts should be made in both basic and clinical researches in the related fields.
Dermatology ; trends ; Forecasting ; Humans ; Venereology ; trends

Acupuncture Therapy ; Adult ; Hoarseness ; therapy ; Humans ; Hysteria ; therapy ; Male

The pattern/symptom differentiation system in acupuncture treatment is lack of the unique characteristics and advantages in theory and clinical practice and it just rigidly adopts the methods of pattern/symptom differentiation of the other disciplines in TCM. In fact, it is necessary to have the unique and more practical theoretic system to guide acupuncture treatment. According to the characteristics of acupuncture in diagnosis and treatment, the acupoints selection based on "disease-symptom-location" combination becomes the law of acupuncture treatment. The acupoints selection based on "disease-symptom-location" combination is the expression to concretize the diagnosis and treatment of disease under the guidance of pattern/syndrome differentiation. Both of them are originated from the general principles of TCM and for the particular disciplines of TCM. The acupoints selection based on "disease-symptom-location" combination benefits the promotion and application of acupuncture.
Acupuncture Points ; Acupuncture Therapy ; Diagnosis, Differential ; Humans ; Meridians

The incidence of gastric cancer is in the fourth place of all cancers in worldwide ,and the fatal-ity rate is in the second place .Standard chemotherapy regimens play an important role in prolonging gastric cancer survival rate.However,most of gastric cancers are in advanced stage when diagnose is finally made .The current medical practice can only meet the limited treatment options .In the last several decades ,study of the molecular mechanisms of gastric cancer gets constant new progress .By inhibiting the human epidermal growth factor receptor 2(Her-2)for advanced gastric cancer,it provides a new treatment for patients.Trastuzumab is a kind of Her -2 monoclonal antibody .It is the first kind of targeted therapy drug for the treatment of metastatic gastric cancer .A combination of trastuzumab with cisplatin and 5-fluorouracil based chemotherapy benefits gastric cancer overall survival.Overexpression of Her -2 provides evidence for the targeted therapy .So we reviewed Her -2 excessive expression of gastric carcinoma in recent years and represented by bead sheet resistance to targeted therapy .In this paper ,research of overpression of Her -2 and targeted threrapy in gastric cancer are summarized .

Objective To investigate the surgical treatment of Maisonneuve injury associated with posterior malleolus fracture under direct visualization via the posterolateral approach.Methods Between January 2008 and June 2015,27 patients with Maisonneuve injury associated with posterior malleolus fracture were treated at our department.They were 18 men and 9 women,aged from 20 to 60 years (average,40.1 years).All fractures and syndesmoses received open reduction under direct visualization and internal fixation via the posterolateral approach.The posterior malleolus fractures were fixed with screws or plate and the syndesmoses fixed using cortical bone screws.Functional results were evaluated using the Baird-Jackson ankle scoring system.Results The patients were followed up for 8 to 30 months (average,18 months).No wound infection,necrosis,dehiscence,lose of reduction or implant failure was found during follow-up visits.All cases got bony union at the last visit.The excellent and good rate was 92.6％.Conclusion Since the posterolateral approach allows good access to the Maisonneuve injury and posterior malleolus fracture under direct visualization,it facilitates accurate direct fracture reduction,stable fixation and early exercise.

Objective To investigate the clinical significance of DNA haploid analysis for malignant degree and prognosis assessment of breast carcinoma. Methods Highclarity Colourful Pathological Analysis System-1000( HPIAS-1000) was used to analyze the DNA haploid of 120 breast carcinoma patients who had been followed up for more than 5 years. All patients were divided into three groups according to histology. 48 advanced differentiation cases, 44 middle differentiation cases and 28 low differentiation cases. Then DNA haploid analysis was made,that is diploid(2C) ,3 - 4C,aneuploid(AN). Results Except for 3 -4C,there were significant differences betweenⅠandⅡgrade ,ⅡandⅢgrade,ⅠandⅢgrade( P

Idiopathic orbital inflammatory pseudotumor(IOIP) is a common orbital disease.It is a nonspecific inflammatory process,and the etiology is still unknown.IOIP occurs at any position of orbit.The clinical manifestation varies according to the anatomic involvement and the degree of inflammation progress.IOIP can clinically mimic many other orbital diseases,especially serious type of this disease can present similar clinical characteristics as the malignant tumor,so it is comprehensive to make a clinical diagnosis.Currently,the diagnosis of IOIP is allowed based on the differentiation from an exclusion of other diseases by a thorough medical history and clinical manifestations,and then acquire some assistant information by radiologic evaluation and laboratory tests and observe the response to steroid treatment.The final diagnosis still requires histopathological examination.